Results 31 to 40 of about 177,696 (251)

The nonlinear structure of linkage disequilibrium [PDF]

Theoretical Population Biology, 2019
AbstractThe allele frequency dependence of the ranges of all measures of linkage disequilibrium is well-known. The maximum values of commonly used parameters such asr2andDvary depending on the allele frequencies at each locus. However, though this phenomenon is recognized and accounted for in many studies, the comprehensive mathematical framework ...
openaire   +4 more sources

Decomposing Multilocus Linkage Disequilibrium [PDF]

Genetics, 2004
Abstract We present a mathematically precise formulation of total linkage disequilibrium between multiple loci as the deviation from probabilistic independence and provide explicit formulas for all higher-order terms of linkage disequilibrium, thereby combining J.
Root Gorelick, Manfred Dietrich Laubichler   +1 more
openaire   +3 more sources

Estimation of genetic parameters and detection of chromosomal regions affecting the major milk proteins and their post translational modifications in Danish Holstein and Danish Jersey cattle [PDF]

, 2016
Linkage disequilibrium plot (r 2) of the DGAT region in the Danish Jersey breed.
Bart Buitenhuis, Grum Gebreyesus, Lotte B. Larsen, Nina A. Poulsen   +3 more
core   +5 more sources

Hydrogel‐Based Capacitive Sensor Model for Ammonium Monitoring in Aquaculture

Advanced Engineering Materials, EarlyView.
Traditional techniques for monitoring aquaculture water quality, particularly ammonium levels, harm fish. This work presents a novel capacitive sensor with an ionic hydrogel transducer to monitor ammonium concentration in real time based on the ammonium‐induced hydrogel dissociation and osmotic pressure. Monitoring aquaculture water quality, especially
Mohammad Mirzaee, Mahdi Askari‐sedeh, Ali Zolfagharian, Mostafa Baghani   +3 more
wiley   +1 more source

LINKAGE DISEQUILIBRIUM IN SUBDIVIDED POPULATIONS [PDF]

Genetics, 1973
ABSTRACT The linkage disequilibrium in a subdivided populaton is shown to be equal to the sum of the average linkage disequilibrium for all subpopulations and the covariance between gene frequencies of the loci concerned. Thus, in a subdivided population the linkage disequilibrium may not be 0 even if the linkage disequilibrium in each ...
Masatoshi Nei, Wen-Hsiung Li, Wen-Hsiung Li   +2 more
openaire   +2 more sources

Integrating Dense Genotyping with High‐Throughput Phenotyping Empowers the Genetic Dissection of Berry Quality and Resilience Traits in Grapevine

Advanced Science, EarlyView.
Researchers develop advanced tools to study grapevine traits like berry quality and stress resilience. A 200K SNP array and high‐throughput phenotyping enable the identification of loci linked to berry shape, sugar content, acidity, and cold tolerance. Functional validation of genes such as NAC08 reveals roles in cold tolerance.
Yuyu Zhang, Yongjian Wang, Michael Henke, Pablo Carbonell‐Bejerano, Zemin Wang, Pierre‐François Bert, Yi Wang, Huayang Li, Junhua Kong, Peige Fan, Zhanwu Dai, Zhenchang Liang   +11 more
wiley   +1 more source

Extent of linkage disequilibrium in chicken

Cytogenetic and Genome Research, 2007
Many of the economically important traits in chicken are multifactorial and governed by multiple genes located at different quantitative trait loci (QTLs). The optimal marker density to identify these QTLs in linkage and association studies is largely determined by the extent of linkage disequilibrium (LD) around them.
Aerts, J., Megens, H.J.W.C., Veenendaal, T., Ovcharenko, I., Crooijmans, R.P.M.A., Gordon, L., Stubbs, L., Groenen, M.A.M., Rodoinov, A., Gaginskaya, E.   +9 more
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Linkage disequilibrium in human populations [PDF]

Proceedings of the National Academy of Sciences, 2003
Whereas the human linkage map appears on limited evidence to be constant over populations, maps of linkage disequilibrium (LD) vary among populations that differ in gene history. The greatest difference is between populations of sub-Saharan origin and populations remotely derived from Africa after a major bottleneck that reduced their ...
Lonjou, Christine, Zhang, Weihua, Collins, Andrew, Tapper, William J., Elahi, Eiram, Maniatis, Nikolas, Morton, Newton E.   +6 more
openaire   +4 more sources

Estimation of linkage disequilibrium in a sample of the United Kingdom dairy cattle population using unphased genotypes [PDF]

, 2003
The association between genetic marker alleles was estimated for two regions of the bovine genome from a random sample of 50 young dairy bulls born in the United Kingdom between 1988 and 1995. Microsatellite marker genotypes were obtained for six markers
Knott, S A, Smith, D, Tenesa, A, Visscher, P M, Ward, D, Williams, J L   +5 more
core  

Prediction of haplotypes for ungenotyped animals and its effect on marker-assisted breeding value estimation [PDF]

, 2010
Background: In livestock populations, missing genotypes on a large proportion of animals are a major problem to implement the estimation of marker-assisted breeding values using haplotypes.
Calus, M.P.L., Mulder, H.A., Veerkamp, R.F.   +2 more
core   +3 more sources