Results 61 to 70 of about 199,519 (335)

Domestication of Tartary Buckwheat Shaped a Regulatory Module for Seedling Salt Tolerance by Targeting the Magnesium Transporter Gene FtMGT2

Advanced Science, EarlyView.
Domestication of Tartary buckwheat is selected for a salt tolerance mechanism involving the magnesium transporter FtMGT2. Its expression is controlled by the FtAGL16‐FtMYB15L module, which is stabilized under salt stress through a competitive interaction that blocks its degradation by the E3 ligase FtBRG1, ultimately boosting Na⁺ efflux and plant ...
Xiang Lu, Yuqi He, Wenfeng Weng, Zebin Liu, Yuanfen Gao, Yaliang Shi, Wei Li, Dili Lai, Mengyu Zhao, Rintu Jha, Hui Zhao, Guangsheng Li, Chaonan Guan, Shuai Shao, Jingjun Ruan, Sun Hee Woo, Yinan Ouyang, Muriel Quinet, Milen I. Georgiev, Alisdair R. Fernie, Congcong Hou, Kaixuan Zhang, Xu Liu, Meiliang Zhou   +23 more
wiley   +1 more source

Relationship between NAFLD and coronary artery disease: A Mendelian randomization study

Hepatology, EarlyView., 2022
Abstract Background and Aims There is an ongoing debate on whether NAFLD is an active contributor or an innocent bystander in the pathogenesis of coronary artery disease (CAD). The aim of the present study was to assess the causal relationship between NAFLD and CAD.
Zhewen Ren, Pomme I. H. G. Simons, Anke Wesselius, Coen D. A. Stehouwer, Martijn C. G. J. Brouwers   +4 more
wiley   +1 more source

Genotype determination for polymorphisms in linkage disequilibrium

BMC Bioinformatics, 2009
Background Genome-wide association studies with single nucleotide polymorphisms (SNPs) show great promise to identify genetic determinants of complex human traits.
Anton-Culver Hoda, Ziogas Argyrios, Garner Chad, Yu Zhaoxia, Schaid Daniel J   +4 more
doaj   +1 more source

Linkage disequilibrium mapping and tagging in sugarcane : [Abstract W233] [PDF]

, 2009
Linkage disequilibrium (LD) in crops, established by domestication and early breeding, can be a valuable basis for mapping the genome. We have assessed LD in sugarcane (Saccharum spp), characterized by one of the most complex crop genomes, with its high ...
Butterfield, Mike, Costet, Laurent, D'Hont, Angélique, Glaszmann, Jean-Christophe, Hoarau, Jean-Yves, Raboin, Louis-Marie   +5 more
core  

Comment on “De Novo Reconstruction of 3D Human Facial Images from DNA Sequence”

Advanced Science, EarlyView.
This comment examines AI‐driven DNA‐based facial reconstruction, focusing on the Difface model. While such technologies promise biomedical and forensic applications, they pose significant ethical, legal, and methodological challenges. We emphasize transparency, benchmarking, and rigorous validation to avoid misinterpretation and misuse.
Jennifer K. Wagner, Nina Claessens, Caitlin M. Maloney, Peter Claes   +3 more
wiley   +1 more source

Linkage disequilibrium in natural populations of Trypanosoma cruzi (flagellate), the agent of Chagas's disease [PDF]

, 1988
We have studied linkage disequilibrium in natural populations of Trypanosoma cruzi, the agent of Chagas' disease, by analyzing (i) a set of 524 stocks from the whole geographical range of the parasite, characterized at four gene loci coding for enzymes; (
Ayala, F.J., Tibayrenc, Michel, Zhang, Q.   +2 more
core  

SNP- and haplotype-based genome-wide association studies for growth, carcass, and meat quality traits in a Duroc multigenerational population [PDF]

, 2016
Average linkage disequilibrium coefficient (r2) values plotted against intermarker distance for all autosomal chromosomes.
Hironori Sakuma, Keiichi Suzuki, Kimiko Kohira, Sachiko Egawa, Satoshi Miyashita, Shinji Arata, Shuji Sato, Takashi Kikuchi, Takatoshi Kojima, Tomomi Saito, Yoshinobu Uemoto   +10 more
core   +6 more sources

Population‐Based Multi‐Omics and Cohort Study Identifying Predictive Biomarkers and Therapeutic Targets for Psoriatic Disease

Advanced Science, EarlyView.
Psoriatic disease (PsD) is a chronic skin disease, with challenges in early risk stratification and drug development. Through gene‐level causal inference framework and expression level validation, combined with longitudinal cohort study, CDSN and PRSS8 have been identified as candidate biomarkers and therapeutic targets for PsD.
Tianxing Wu, Jialiang Luo, Haoyuan Qiu, Weijie Shao, Yueyang Lu, Meixuan Luo, Zhaofeng Lin, Yan Zhang, Libo Zhang, Hong Wang, Jia Zhou, Guangfeng Ruan, Peihua Cao, Daming Zuo   +13 more
wiley   +1 more source

A Targeted Capture Linkage Map Anchors the Genome of the Schistosomiasis Vector Snail, Biomphalaria glabrata

G3: Genes, Genomes, Genetics, 2017
The aquatic planorbid snail Biomphalaria glabrata is one of the most intensively-studied mollusks due to its role in the transmission of schistosomiasis. Its 916 Mb genome has recently been sequenced and annotated, but it remains poorly assembled.
Jacob A. Tennessen, Stephanie R. Bollmann, Michael S. Blouin   +2 more
doaj   +1 more source

A Trypsin‐Like Serine Protease ZmNAL1a Fine‐Tunes Maize Floral Transition and Flowering Time

Advanced Science, EarlyView.
This study identifies a trypsin‐like serine protease, ZmNAL1a, that moves from leaves to the shoot apical meristem. ZmNAL1a promotes the floral transition by degrading TOPLESS‐like corepressor REL2, which thereby enhances the expression of key flowering genes through elevating histone acetylation and relieving REL2–ZmEREBP147‐mediated transcriptional ...
Nan Li, Qiang Ning, Zhen Li, Qian Zhang, Peilu Zhu, Jimin Zhan, Yunfu Li, Zhen Li, Liang Dong, Qing Xiong, Jiahao Liao, Jie Liu, David Jackson, Munenori Kitagawa, Zuxin Zhang, Lei Liu   +15 more
wiley   +1 more source