Results 61 to 70 of about 537,873 (344)

Decomposing Multilocus Linkage Disequilibrium [PDF]

open access: yesGenetics, 2004
Abstract We present a mathematically precise formulation of total linkage disequilibrium between multiple loci as the deviation from probabilistic independence and provide explicit formulas for all higher-order terms of linkage disequilibrium, thereby combining J.
Root Gorelick   +1 more
openaire   +3 more sources

SOFTWARE FOR GENETIC MAPPING AND ANALYSIS OF MARKER/TRAIT ASSOCIATIONS

open access: yesОвощи России, 2016
The paper presents the information about technical tools and software wide used for statistic calculations and detection of linkage disequilibrium marker/trait as well as association between traits/genes and molecular markers based on identification of ...
N. V. Kocherina, Yu. V. Chesnokov
doaj   +1 more source

Hydrogel‐Based Capacitive Sensor Model for Ammonium Monitoring in Aquaculture

open access: yesAdvanced Engineering Materials, EarlyView.
Traditional techniques for monitoring aquaculture water quality, particularly ammonium levels, harm fish. This work presents a novel capacitive sensor with an ionic hydrogel transducer to monitor ammonium concentration in real time based on the ammonium‐induced hydrogel dissociation and osmotic pressure. Monitoring aquaculture water quality, especially
Mohammad Mirzaee   +3 more
wiley   +1 more source

JLIN: A java based linkage disequilibrium plotter

open access: yesBMC Bioinformatics, 2006
Background A great deal of effort and expense are being expended internationally in attempts to detect genetic polymorphisms contributing to susceptibility to complex human disease. Techniques such as Linkage Disequilibrium mapping are being increasingly
McCaskie Pamela A   +2 more
doaj   +1 more source

Integrating Dense Genotyping with High‐Throughput Phenotyping Empowers the Genetic Dissection of Berry Quality and Resilience Traits in Grapevine

open access: yesAdvanced Science, EarlyView.
Researchers develop advanced tools to study grapevine traits like berry quality and stress resilience. A 200K SNP array and high‐throughput phenotyping enable the identification of loci linked to berry shape, sugar content, acidity, and cold tolerance. Functional validation of genes such as NAC08 reveals roles in cold tolerance.
Yuyu Zhang   +11 more
wiley   +1 more source

The nonlinear structure of linkage disequilibrium [PDF]

open access: yesTheoretical Population Biology, 2019
AbstractThe allele frequency dependence of the ranges of all measures of linkage disequilibrium is well-known. The maximum values of commonly used parameters such asr2andDvary depending on the allele frequencies at each locus. However, though this phenomenon is recognized and accounted for in many studies, the comprehensive mathematical framework ...
openaire   +4 more sources

Detection of QTL for Carcass Quality on Chromosome 6 by Exploiting Linkage and Linkage Disequilibrium in Hanwoo [PDF]

open access: yesAsian-Australasian Journal of Animal Sciences, 2012
The purpose of this study was to improve mapping power and resolution for the QTL influencing carcass quality in Hanwoo, which was previously detected on the bovine chromosome (BTA) 6.
J.-H. Lee, Y. Li, J.-J. Kim
doaj   +1 more source

A simple correction for multiple testing for single-nucleotide polymorphisms in linkage disequilibrium with each other.

open access: yesAmerican Journal of Human Genetics, 2004
In this report, we describe a simple correction for multiple testing of single-nucleotide polymorphisms (SNPs) in linkage disequilibrium (LD) with each other, on the basis of the spectral decomposition (SpD) of matrices of pairwise LD between SNPs.
D. Nyholt
semanticscholar   +1 more source

The Non‐Coding Regulatory Variant rs2863002 at chr11p11.2 Increases Neuroblastoma Risk by Affecting HSD17B12 Expression and Lipid Metabolism

open access: yesAdvanced Science, EarlyView.
The SNP rs2863002 at the 11p11.2 locus, identified through GWAS, is associated with an increased risk of neuroblastoma. The rs2863002‐C allele impairs the binding of the transcription factor GATA3, resulting in upregulation of the HSD17B12 gene.
Teresa Maiorino   +20 more
wiley   +1 more source

Extent of linkage disequilibrium in chicken

open access: yesCytogenetic and Genome Research, 2007
Many of the economically important traits in chicken are multifactorial and governed by multiple genes located at different quantitative trait loci (QTLs). The optimal marker density to identify these QTLs in linkage and association studies is largely determined by the extent of linkage disequilibrium (LD) around them.
Aerts, J.   +9 more
openaire   +3 more sources

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