Results 101 to 110 of about 6,597,900 (338)
RAD50 missense variants differentially affect the DNA damage response and mitotic progression
RAD50 incorporates into the MRN complex and initiates the DNA damage response. Furthermore, RAD50 promotes mitotic progression. RAD50 missense variants capable of forming an MRN complex supported the DNA damage response and mitotic features to different extents in complementation experiments, indicating these functions are separable and might impact ...
Hanna Redeker +9 more
wiley +1 more source
Die nachhaltige Bewahrung einer Forschungsdatenbank durch Linked Data. Laut welchem Vokabular?
Linked Data bietet die Möglichkeit nicht nur normkonforme Datensätze zur Verfügung zu stellen sonder auch nachhaltig und langfristig Metadaten zu bewahren, wenn diese zu Linked Data Vokabularen verknüpft sind. Aber welches Vokabular soll man nutzen?
Francesco Gelati
doaj +1 more source
Mapping the evolution of mitochondrial complex I through structural variation
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin +2 more
wiley +1 more source
Data for the study of sex‐linked inheritance in Drosophila [PDF]
T. H. Morgan, Eleth Cattell
openalex +1 more source
Question Answering on Linked Data: Challenges and Future Directions
Question Answering (QA) systems are becoming the inspiring model for the future of search engines. While recently, underlying datasets for QA systems have been promoted from unstructured datasets to structured datasets with highly semantic-enriched ...
Endris, Kemele +6 more
core +1 more source
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
A Data Link between Small Computers and a CDC 6600 [PDF]
Sypko W. Andreae, Robert Lafore
openalex +1 more source
Session on Linked Open Data; part of Sunoikisis Digital Cultural Heritage, Fall 2019. Outline: The five stars of Linked Open Data and beyond LOD theory, values & content negotiation RDF & ontologies Case study 1: CuCoO Case study 2: HuCit Introduction to Sparql and ...
Bodard, Gabriel +2 more
openaire +2 more sources
Explaining clusters with inductive logic programming and linked data [PDF]
Knowledge Discovery consists in discovering hidden regularities in large amounts of data using data mining techniques. The obtained patterns require an interpretation that is usually achieved using some background knowledge given by experts from several ...
d'Aquin, Mathieu +2 more
core
Plasmodium falciparum gametogenesis essential protein 1 (GEP1) is a transmission‐blocking target
This study shows Plasmodium falciparum GEP1 is vital for activating sexual stages of malarial parasites even independently of a mosquito factor. Knockout parasites completely fail gamete formation even when a phosphodiesterase inhibitor is added. Two single‐nucleotide polymorphisms (V241L and S263P) are found in 12%–20% of field samples.
Frederik Huppertz +5 more
wiley +1 more source

