Results 101 to 110 of about 2,706,002 (277)

The atypical KRASQ22K mutation directs TGF‐β response towards partial epithelial‐to‐mesenchymal transition in patient‐derived colorectal cancer tumoroids

Molecular Oncology, EarlyView.
TGF‐β has a complex role in cancer, exhibiting both tumor‐suppressive and tumor‐promoting properties. Using a series of differentiated tumoroids, derived from different stages and mutational background of colorectal cancer patients, we replicate this duality of TGF‐β in vitro. Notably, the atypical but highly aggressive KRASQ22K mutation rendered early‐
Theresia Mair, Philip König, Milena Mijović, Jessica Kalla, Anil Baskan, Loan Tran, Kristina Draganić, Pedro Morata Saldaña, Carlos Uziel Pérez Malla, Janette Pfneissl, Andreas Tiefenbacher, Julijan Kabiljo, Velina S. Atanasova, Lisa Wozelka‐Oltjan, Leonhard Müllauer, Michael Bergmann, Raheleh Sheibani‐Tezerji, Gerda Egger   +17 more
wiley   +1 more source

Addressing Dementia Through Analysis of Population Traits and Risk Factors (ADAPTOR) project: dementia incidence in an Australian cohort

Public Health Research & Practice, 2023
Smriti Nepal , Xenia Dolja-Gore, Dominic Cavenagh , Catherine D'Este , Kaarin J Anstey, Henry Brodaty , Heidi J Welberry, Anita MY Goh , Martin McNamara   +8 more
doaj   +1 more source

Design considerations for a seismograph network for Oaxaca State, Mexico with telemetry of data by radio link to Mexico City

, 1978
R B Hayman
openalex   +1 more source

Airborne data link study report [PDF]

, 1996
Albert J. Rehmann
openalex   +1 more source

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

Molecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes, Mario Ortega Duran, Solon Karapanagiotis, Alistair Martin, Meiling Gao, Riccardo Masina, Ramona Woitek, James Tanner, Fleur Tippin, Justine Kane, Jonathan Lay, Anja Brouwer, Stephen‐John Sammut, Suet‐Feung Chin, Davina Gale, Dana W. Y. Tsui, Sarah‐Jane Dawson, Nitzan Rosenfeld, Maurizio Callari, Oscar M. Rueda, Carlos Caldas   +20 more
wiley   +1 more source

Outer continental shelf program. First quarterly report, January 1--March 31, 1977. [Underwater-acoustic-data-link tests at Elephant Butte Lake in New Mexico]

, 1977
D.H. Denton
openalex   +2 more sources

Relaxing the instantiation link: Towards a content-based data model for information retrieval [PDF]

, 1996
Youssef Lahlou, Noureddine Mouaddib
openalex   +1 more source

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

Molecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser, Florian Krumbach, Eyleen Corrales, Geoffroy Andrieux, Christian Preisinger, Franziska Liss, Alexandra Golzmann, Melanie Boerries, Kerstin Becker, Ruth Knüchel, Stefan Garczyk, Bernhard Lüscher   +11 more
wiley   +1 more source

Semantic technologies and linked data for the Italian PA: the case of data.cnr.it

JLIS.it, 2013
Governmental data are being published in many countries, providing an unprecedented opportunity to create innovative services and to increase societal awareness about administration dynamics.
Aldo Gangemi
doaj   +2 more sources

Introduction to Linked Data

, 2019
The learning objective of this presentation is to understand the aims and principles of Linked Data. Concepts covered include Linked Data and the Semantic Web, how ontologies and their structures are expressed, creating RDF triples, and SPARQL. Practical sections of this material include exercises to examine the Wikidata knowledge graph, compare a ...
openaire   +3 more sources