Results 71 to 80 of about 6,597,900 (338)

C‐mannosylation promotes ADAMTS1 activation and secretion in human testicular germ cell tumor NEC8 cells

open access: yesFEBS Letters, EarlyView.
C‐mannosylation is a unique form of protein glycosylation. In this study, we demonstrated that ADAMTS1 is C‐mannosylated at Trp562 and Trp565 in human testicular germ cell tumor NEC8 cells. We found that C‐mannosylation of ADAMTS1 is essential for its secretion, processing, enzymatic activity, and ability to promote vasculogenic mimicry. These findings
Takato Kobayashi   +5 more
wiley   +1 more source

From MARC silos to Linked Data silos?

open access: yeso-bib. Das offene Bibliotheksjournal, 2017
Libraries are opening up their bibliographic metadata as Linked Data. However, they have all used different data models for structuring their bibliographic data.
Osma Suominen, Nina Hyvönen
doaj   +1 more source

Tracking Federated Queries in the Linked Data [PDF]

open access: yes, 2015
Federated query engines allow data consumers to execute queries over the federation of Linked Data (LD). However, as federated queries are decomposed into potentially thousands of subqueries distributed among SPARQL endpoints, data providers do not know ...
Desmontils, Emmanuel   +3 more
core   +2 more sources

A linked data approach to publishing complex scientific workflows [PDF]

open access: yes, 2011
Past data management practices in many fields of natural science, including climate research, have focused primarily on the final research output - the research publication - with less attention paid to the chain of intermediate data results and their ...
Callaghan, Sarah   +6 more
core   +1 more source

The multidrug and toxin extrusion (MATE) transporter DTX51 antagonizes non‐cell‐autonomous HLS1–AMP1 signaling in a region‐specific manner

open access: yesFEBS Letters, EarlyView.
The Arabidopsis mutants hls1 hlh1 and amp1 lamp1 exhibit pleiotropic developmental phenotypes. Although the functions of the causative genes remain unclear, they act in the same genetic pathway and are thought to generate non‐cell‐autonomous signals.
Takashi Nobusawa, Makoto Kusaba
wiley   +1 more source

Transforming meteorological data into Linked Data [PDF]

open access: yesSemantic Web, 2013
This work has been supported by the Spanish project myBigData (TIN2010-17060).
Atemezing, Ghislain   +7 more
openaire   +3 more sources

Chem# - Semantically Enriched Linked Open Chemical Data [PDF]

open access: yes, 2011
The problem: Vast quantities of chemical data (e.g. crystal structures, NMR spectra, experimental reports) are generated every day. The majority of this data is never published, and the data that is published is fragmented,trapped in legacy formats and ...
Adams, Sam   +4 more
core  

Ergothioneine supplementation improves pup phenotype and survival in a murine model of spinal muscular atrophy

open access: yesFEBS Letters, EarlyView.
Spinal muscular atrophy (SMA) is a genetic disease affecting motor neurons. Individuals with SMA experience mitochondrial dysfunction and oxidative stress. The aim of the study was to investigate the effect of an antioxidant and neuroprotective substance, ergothioneine (ERGO), on an SMNΔ7 mouse model of SMA.
Francesca Cadile   +8 more
wiley   +1 more source

The nicotinamide hypothesis revisited—plant defense signaling integrating PARP, nicotinamide, nicotinic acid, epigenetics, and glutathione

open access: yesFEBS Letters, EarlyView.
Nicotinamide (NIC) and nicotinic acid (NIA) are proposed as stress signaling compounds in plants. Oxidative stress may lead to single strand breaks (SSB) in DNA, which activate poly(ADP‐ribose) polymerase (PARP). NIC and NIA are then formed from NAD. NIC and NIA can promote epigenetic changes leading to the expression of defense genes specific for the ...
Torkel Berglund, Anna B. Ohlsson
wiley   +1 more source

Linked Data Authorization Platform

open access: yesIEEE Access, 2018
The expansion of the smart devices, the growing popularity of the social networks, and the wide spread of the corporate services impose huge amounts of heterogeneous data to be generated and stored in separate silos on a daily basis.
Riste Stojanov   +3 more
doaj   +1 more source

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