Results 71 to 80 of about 2,634,309 (286)

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

DASL: An Index for Enhancing Tail Latency, Microarchitecture Friendliness, and Restructuring Overhead

open access: yesIEEE Access
The skip list is a popular in-memory index in modern database systems. It maintains multiple levels of lists, which makes it efficient in traversing sorted data. In addition, it is flexible in inserting and deleting data, while avoiding the restructuring
Hojin Shin   +4 more
doaj   +1 more source

The path to microRNA therapeutics in psychiatric and neurodegenerative disorders

open access: yesFrontiers in Genetics, 2012
The microRNA (miRNA) class of noncoding RNAs exhibit a diverse range of regulatory roles in neuronal functions that are conserved from lower vertebrates to primates.
Anthony WS Chan, Jannet eKocerha
doaj   +1 more source

Thematic list of projects using linked data relating to Aboriginal and Torres Strait Islander people [PDF]

open access: yes
This report contains an alphabetical listing and description of past (published since 1991), current and planned data linkage studies relating to Aboriginal and Torres Strait Islander people.

core  

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

Methodology of the biological risk classification of animal pathogens in Belgium [PDF]

open access: yes, 2010
The biological hazards posed by micro-organisms have lead to their categorisation into risk groups and the elaboration of classification lists. Current classification systems rely on criteria defined by the World Health Organization, which cover the ...
Boyen, Filip   +8 more
core   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

A comprehensive of transforms, Gabor filter and k-means clustering for text detection in images and video

open access: yesApplied Computing and Informatics, 2016
The present paper presents one of the efficient approaches toward multilingual text detection for video indexing. In this paper, we propose a method for detecting textlocated in varying and complex background in images/video.
V.N. Manjunath Aradhya, M.S. Pavithra
doaj   +1 more source

New Methodological Developments for the International Comparison Program [PDF]

open access: yes
The paper explains new methodology that was used in the 2005 International Comparison Program (ICP) that compared the relative price levels and GDP levels across 146 countries.
Diewert, Erwin
core  

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

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