Results 81 to 90 of about 1,479,186 (249)

Open data and linked data

open access: yes, 2007
Paul Miller, Linked Data - the real Semantic Web? <em> Nodalities </em> , May 22, 2007.  (Thanks to Peter Murray-Rust.)
openaire   +1 more source

Opening and Linking Agricultural Research Data

open access: yesD-Lib Magazine, 2014
A Research Data Alliance (RDA) Interest Group has formed around a community of scientists and researchers who wish to make agricultural data, information, and knowledge more accessible. The objective of the Agricultural Data Interest Group is to get together active representatives of the major international institutions that work on agricultural ...
Dzale Yeumo, Windpouire Esther   +2 more
openaire   +4 more sources

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Large-scale regulatory and signaling network assembly through linked open data. [PDF]

open access: yesDatabase (Oxford), 2021
Lefebvre M   +4 more
europepmc   +1 more source

Visualizing Linked Open Data

open access: yes, 2013
A query language called SPARQL has been developed to extract knowledge from Linked Data. Composing a SPARQL query is still mainly for the technical savvy. To expose the potential of Linked Data to other less-technical domains, novel visualization techniques are essential.
Waagmeester, Andra   +2 more
openaire   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

open access: yesFEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López   +2 more
wiley   +1 more source

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