Results 31 to 40 of about 4,098,264 (291)

Engineering a Highly Defective Stable UiO-66 with Tunable Lewis- Brønsted Acidity: The Role of the Hemilabile Linker

open access: yesJournal of the American Chemical Society, 2020
The stability of metal–organic frameworks (MOFs) typically decreases with an increasing number of defects, limiting the number of defects that can be created and limiting catalytic and other applications. Herein, we use a hemilabile (Hl) linker to create
Xiao Feng   +14 more
semanticscholar   +1 more source

Modulating Linker Composition of Haptens Resulted in Improved Immunoassay for Histamine. [PDF]

open access: yes, 2019
Histamine (HA) is an important food contaminant generated during food fermentation or spoilage. However, an immunoassay for direct (derivatization free) determination of HA has rarely been reported due to its small size to induce the desired antibodies ...
Dong, Jie-Xian   +9 more
core   +1 more source

Design, Synthesis and Evaluation of N-pyrazinylbenzamides as Potential Antimycobacterial Agents

open access: yesMolecules, 2018
Three series of N-(pyrazin-2-yl)benzamides were designed as retro-amide analogues of previously published N-phenylpyrazine-2-carboxamides with in vitro antimycobacterial activity. The synthesized retro-amides were evaluated for in vitro growth inhibiting
Jan Zitko   +7 more
doaj   +1 more source

Protective Efficacy of Recombinant Influenza Hemagglutinin Ectodomain Fusions

open access: yesViruses, 2021
In current seasonal influenza vaccines, neutralizing antibody titers directed against the hemagglutinin surface protein are the primary correlate of protection. These vaccines are, therefore, quantitated in terms of their hemagglutinin content.
Nidhi Mittal   +9 more
doaj   +1 more source

Nucleus-specific linker histones Hho1 and Mlh1 form distinct protein interactions during growth, starvation and development in Tetrahymena thermophila [PDF]

open access: yes, 2019
Chromatin organization influences most aspects of gene expression regulation. The linker histone H1, along with the core histones, is a key component of eukaryotic chromatin.
Pearlman, Ronald E.   +7 more
core   +1 more source

Blockade of Human α7 Nicotinic Acetylcholine Receptor by α-Conotoxin ImI Dendrimer: Insight from Computational Simulations

open access: yesMarine Drugs, 2019
Nicotinic acetylcholine receptors (nAChRs) are ligand-gated ion channels that are involved in fast synaptic transmission and mediated physiological activities in the nervous system.
Xiaoxiao Xu   +4 more
doaj   +1 more source

A versatile characterization of poly(N-isopropylacrylamideco- N,N'-methylene-bis-acrylamide) hydrogels for composition, mechanical strength, and rheology [PDF]

open access: yes, 2013
Poly(N-isopropylacrylamide-co-N,N"-methylene-bisacrylamide) (P(NIPAAm-co-MBA)) hydrogels were prepared in water using redox initiator. The copolymer composition at high conversion (> 95%) was determined indirectly by HPLC (high performance liquid ...
Chetty, A.   +7 more
core   +1 more source

Microwave (MW), Ultrasound (US) and Combined Synergic MW-US Strategies for Rapid Functionalization of Pharmaceutical Use Phenols

open access: yesMolecules, 2018
Increasingly stringent regulations aimed at protection of the natural environment have stimulated the search for new synthetic methodologies in organic and medicinal chemistry having no or minimum harmful effect.
Anna Pawełczyk   +3 more
doaj   +1 more source

Trends in the Development of Antibody-Drug Conjugates for Cancer Therapy

open access: yesAntibodies, 2023
In cancer treatment, the first-generation, cytotoxic drugs, though effective against cancer cells, also harmed healthy ones. The second-generation targeted cancer cells precisely to inhibit their growth.
Chi Hun Song   +5 more
doaj   +1 more source

Functionalization of Iron Nanoparticles with Linkers for Removal of Pollutants in Water [PDF]

open access: yesWater Harvesting Research, 2022
Today, quality monitoring of water resources played an influential role in its exploitation and use. Water sources usually contain heavy metals in minor concentrations.
Raziyeh Shamshirgaran   +3 more
doaj   +1 more source

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