Results 101 to 110 of about 79,767 (263)

Seed lipid profiles of perennial ryegrass: Global patterns and differentiation of ryegrass cultivars and Epichloë endophytes

open access: yesGrassland Research, EarlyView.
Seed lipid profiles from three ryegrass cultivars infected with AR501 show distinct changes in the medium‐chain diacylglycerols, triacylglycerols and sphingolipids. The differential peal LN745.5052_5.78 can be identified as PG 16:0_18:2 with the supporting ms2 fragmentation spectrum. Abstract Background Forage perennial ryegrass (Lolium perenne L.) has
Mingshu Cao   +6 more
wiley   +1 more source

Health effects of Conjugated Linoleic Acid

open access: yesMajallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, 2018
Background: Linoleic acid is converted to various isomers under the conditions of enzymatic and biohydrogenation in the ruminal ruminant medium, called linoleic acid conjugate, which is a hybrid.
M Rahdari
doaj  

Majorbio Cloud: An integrated platform for single‐omics and integrated multi‐omics analysis of microbiome and metabolome

open access: yesiMetaOmics, EarlyView.
Advances in sequencing and mass spectrometry have propelled life sciences into the multi‐omics era. Metabolomics and microbiomics are widely applied across various research fields, yet massive data analysis faces challenges like limited tool functionality and high technical barriers.
Jianhua Zhao   +16 more
wiley   +1 more source

Harnessing microbial metabolism and nutrition to target the gut–mammary axis for better livestock production and health

open access: yesiMetaOmics, EarlyView.
The gut–mammary axis integrates intestinal health with mammary function through neural, endocrine, and immune pathways. Nutritional interventions (probiotics, prebiotics, metabolites) improve gut microecology, generating microbial signals that travel via the axis to the mammary gland. There, they relieve inflammation, enhance milk quality and lactation,
Aolong Zhou   +29 more
wiley   +1 more source

A synthetic community promotes macadamia growth via root‐microbe interactions and systemic plant responses

open access: yesiMetaOmics, EarlyView.
We employed an 18‐month pot experiment and an integrated multi‐omics approach to elucidate the potential mechanisms underlying synthetic community (SynCom)‐mediated macadamia growth promotion. SynCom inoculation enhanced soil nitrogen cycling and potential nutrient (e.g., iron) acquisition.
Xiaofang Yao   +5 more
wiley   +1 more source

Metabolic feature profiling and metabolic vulnerability in acute lymphoblastic leukemia

open access: yesInterdisciplinary Medicine, EarlyView.
For the first time, our study develops a novel metabolic classification and subtyping program, metabolic reprogramming‐based classifier for acute lymphoblastic leukemia, using internal PDT‐ALL‐2016 and external cohorts, which dissects metabolic profiling, clinical outcome, and therapeutic vulnerability for precision metabolic intervention in ALL ...
Xiaojie Liang   +13 more
wiley   +1 more source

CIGARETTE SMOKING AND LINOLEIC ACID

open access: yesThe Lancet, 1989
Berns, M.A.M., Katan, M.B.
openaire   +3 more sources

Enhanced peripheral blood mononuclear cell lipid metabolism drives poor immunotherapy response via ferroptotic stress‐induced T cell exhaustion in hepatocellular carcinoma

open access: yesInterdisciplinary Medicine, EarlyView.
Integrated multi‐omics reveals that CD36‐mediated lipid overload in PBMCs drives T cell exhaustion via sub‐lethal ferroptotic stress and AKT suppression. This systemic metabolic signature serves as a robust predictor of immunotherapy response in HCC, suggesting that modulating lipid metabolism can rescue immune fitness.
Ying Zhu   +6 more
wiley   +1 more source

Maternal linoleic acid-rich diet ameliorates bilirubin neurotoxicity in offspring mice

open access: yesCell Death Discovery
Hyperbilirubinaemia is a prevalent condition during the neonatal period, and if not promptly and effectively managed, it can lead to severe bilirubin-induced neurotoxicity.
Ding Yan   +17 more
doaj   +1 more source

Mitochondria‐targeted nanomedicine for cancer therapy: Targeting strategies, therapeutic mechanisms, and translational challenges

open access: yesInterdisciplinary Medicine, EarlyView.
This review highlights recent advances in mitochondria‐targeted nanomedicine for cancer therapy. It summarizes key targeting strategies and delineates four principal therapeutic mechanisms: oxidative stress–induced mitochondrial dysfunction, disruption of energy metabolism, direct mitochondrial damage, and induction of immunogenic cell death.
Linfeng Xiao   +7 more
wiley   +1 more source

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