Results 81 to 90 of about 2,518,882 (259)

Innovative Test Strip‐Based Colorimetric Sensors Integrated With Affinity Chromatography: Acetylcholinesterase Inhibitor Screening Breakthrough in Lycium Barbarum Leaves

Advanced Science, EarlyView.
Schematic diagrams illustrating the breakthrough in the screening of AChE inhibitors from LBL, and the research process of the pharmacodynamics of the NCP are presented. ABSTRACT Current Alzheimer's drugs exhibit limited effectiveness, highlighting the necessity for multi‐target treatments.
Yuping Sa, Hui Yuan, Jingui Ma, Zhigang Yang, Mei Wang, Weibiao Wang, Lingling Yang, Fen Ma, Weiman Zhang, Gidion Wilson Mening'oo, Guoning Chen, Xueqin Ma   +11 more
wiley   +1 more source

Conjugated Linoleic Acid and dairy cows: metabolism, reproduction and products quality [PDF]

, 2010
The aim of this dissertation was to evaluate in dairy cows the effects of the supplementation of Conjugated Linoleic Acid, as natural feed (pasture) or as additive (CLA rumen protected), on quality of dairy products and on cow metabolism and ...
Esposito, Giulia
core   +1 more source

Linoleic acid-induced endothelial activation

Journal of Lipid Research, 2004
Hypertriglyceridemia, an important risk factor of atherosclerosis, is associated with increased circulating free fatty acids. Research to date indicates that linoleic acid (LA), the major fatty acid in the American diet, may be atherogenic by activating ...
Viswanathan Saraswathi, Guoyao Wu, Michal Toborek, Bernhard Hennig   +3 more
doaj   +1 more source

Effects of heating process of soybeans on ruminal production of conjugated linoleic acids and trans-octadecenoic acids in situ [PDF]

, 2006
The effects of two thermal treatments of soybeans, i.e. roasting (150˚C dry heat) and extrusion (140-150˚C), on conjugated linoleic acids (CLA) and trans-octadecenoic acids (trans-C18:1) productions obtained throughout ruminal C18:2 biohydrogenation in ...
Troegeler-Meynadier, Annabelle, Nicot, Marie-Claude, Enjalbert, Francis   +2 more
core   +1 more source

An Effector TaCRVP From Tuta Absoluta Oral Secretion Impairs H2O2‐Mediated Plant Defense by Targeting Tomato SlCAT2

Advanced Science, EarlyView.
The Tuta absoluta salivary effector TaCRVP subverts tomato immunity by hijacking host catalase SlCAT2. Through a sophisticated dual mechanism, TaCRVP simultaneously promotes SlCAT2 tetramerization for activation and blocks its SlAdBiL‐mediated degradation for stabilization.
Jianquan Yan, Youdan Zhang, Zhujun Wang, Huatao Tang, Huiping Liu, Zi Chen, Shuai Liu, Jiayi Shi, Lu Peng, Youming Hou   +9 more
wiley   +1 more source

Essential lipid autacoids rewire mitochondrial energy efficiency in metabolic dysfunction‐associated fatty liver disease

Hepatology, EarlyView., 2022
Increased liver content of DHA‐derived small lipid autacoids (i.e resolvin D1 and maresin 1) associates with enhanced mitochondrial oxidative phosphorylation, fatty acid β‐oxidation and bioenergetic metabolic flux. These features provide hepatic protection from steatotic, pro‐inflammatory and fibrogenic insults.
Cristina López‐Vicario, David Sebastián, Mireia Casulleras, Marta Duran‐Güell, Roger Flores‐Costa, Ferran Aguilar, Juan José Lozano, Ingrid W. Zhang, Esther Titos, Jing X. Kang, Antonio Zorzano, Makoto Arita, Joan Clària   +12 more
wiley   +1 more source

Inclusion of fresh forage in the ration for dairy cows: effects on CLA and trans C18:1 isomers content of milk fat

Italian Journal of Animal Science, 2010
Milk fat is the richest natural source of conjugated linoleic acid (CLA) isomers. The 9-cis, 11-trans CLA isomer (rumenic acid, RA) origins from two pathways: as an intermediate of the rumen biohydrogenation process of linoleic acid or as the product of ...
P. Secchiari, M. Antongiovanni, M. Mele, M. Del Viva, A. Serra   +4 more
doaj   +1 more source

Maternal high linoleic acid alters placental fatty acid composition [PDF]

, 2020
Fetal development is modulated by maternal nutrition during pregnancy. The dietary intake of linoleic acid (LA), an essential dietary n-6 polyunsaturated fatty acid (PUFA), has increased.
Hryciw, Deanne H, Shrestha, Nirajan, Kent, Nykola L, Andrew J. McAinch, Shrestha, N, Kent, NL, Cuffe, James S. M., Holland, OJ, Anthony V. Perkins, Kent, Nykola L., McAinch, Andrew, Cuffe, James SM, Nykola L. Kent, Perkins, AV, James S. M. Cuffe, Holland, Olivia J., McAinch, AJ, Perkins, Anthony V, Perkins, Anthony V., Holland, Olivia J, Cuffe, JSM, McAinch, Andrew J., Nirajan Shrestha, McAinch, Andrew J, Hryciw, DH, Hryciw, Deanne H., Deanne H. Hryciw, Olivia J. Holland   +27 more
core   +1 more source

Targeting the PHB2–ACSL3 Lipid‐Remodeling Axis Overcomes Cisplatin Resistance by Restoring Ferroptosis in Gastric Cancer

Advanced Science, EarlyView.
ABSTRACT Platinum‐based chemotherapy resistance remains a major obstacle in gastric cancer (GC) treatment. Through integrated transcriptomic profiling of cisplatin‐resistant xenografts and pharmacogenomic interrogation of the NCI‐60 dataset, we identified Prohibitin‐2 (PHB2) as a previously unrecognized determinant of chemoresistance.
Liang Xu, Wanying Xiang, Xinyue Wang, Yue Pan, Jing Gao, Jiezhen Yang, Yufei Wang, Zhipu Zhu, Man Tong, Lei Jin, Yan Ye   +10 more
wiley   +1 more source

Effect of dietary supplementation with conjugated linoleic acid on markers of calcium and bone metabolism in healthy adult men.

, 2005
INTRODUCTION: Conjugated linoleic acid (CLA) has been shown to positively influence calcium and bone metabolism in experimental animals and cells in culture, but there are limited human data available.
Mullen, A, Cashman, KD, Jewell, C, Roche, HM, Doyle, L, Nugent, AP   +5 more
core   +1 more source