Results 71 to 80 of about 107,686 (309)

Radiohomogeneity of H3- and C14-labeled linoleic acid in vivo

Journal of Lipid Research, 1965
A mixture of linoleic acid-1-C14 and linoleic acid labeled with H3 in the chain was administered to rats, and the H3/C14 ratio in the linoleic acid recovered from liver and adipose tissue of the rat was compared with that in the administered mixture ...
Demetrios Sgoutas, Moon Ja Kim, Fred A. Kummerow   +2 more
doaj   +1 more source

Effect of dietary supplementation with conjugated linoleic acid on markers of calcium and bone metabolism in healthy adult men.

, 2005
INTRODUCTION: Conjugated linoleic acid (CLA) has been shown to positively influence calcium and bone metabolism in experimental animals and cells in culture, but there are limited human data available.
Mullen, A, Cashman, KD, Jewell, C, Roche, HM, Doyle, L, Nugent, AP   +5 more
core   +1 more source

Biosynthesis of Sciadonic Acid Derived from Gymnosperms with Anti‐Colitis Activity

Advanced Science, EarlyView.
This study establishes an efficient Yarrowia lipolytica platform for unusual sciadonic acid (SCA) production and assess the anti‐colitis efficacy in mice of SCA, supporting its potential as a novel therapeutic lipid. ABSTRACT Sciadonic acid (SCA), Δ5‐unsaturated fatty acid with anti‐inflammatory and lipid‐regulatory properties, is predominantly derived
Yadi Gao, Wei Liu, Xiuping Liang, Jie Bai, Hong Chang, Wenchao Chen, Mohamed A. Farag, Jianbo Xiao, Huifeng Jiang, Jiasheng Wu, Lili Song   +10 more
wiley   +1 more source

Effects of heating process of soybeans on ruminal production of conjugated linoleic acids and trans-octadecenoic acids in situ [PDF]

, 2006
The effects of two thermal treatments of soybeans, i.e. roasting (150˚C dry heat) and extrusion (140-150˚C), on conjugated linoleic acids (CLA) and trans-octadecenoic acids (trans-C18:1) productions obtained throughout ruminal C18:2 biohydrogenation in ...
Troegeler-Meynadier, Annabelle, Nicot, Marie-Claude, Enjalbert, Francis   +2 more
core  

CEBPG‐Mediated Palmitic Acid Adaptation of Cancer‐Associated Fibroblasts Drives Metastasis of Oral Squamous Cell Carcinoma

Advanced Science, EarlyView.
This study reveals a metabolic signaling axis in the OSCC microenvironment where palmitic acid (PA) drives the activation of CAFs. PA uptake triggers CEBPG‐dependent epigenetic remodeling to upregulate ERN1 and TMBIM6, thereby mitigating ER stress. This adaptive program sustains CAF survival and the pro‐metastatic phenotype, establishing this pathway ...
Yiling Duan, Yitong Li, Yufei Wu, Xiao Yang, Rui Li, Hui Zhao, Zhengjun Shang   +6 more
wiley   +1 more source

Conjugated linoleic acid as a novel insecticide targeting the agricultural pest Leptinotarsa decemlineata.

PLoS ONE, 2019
The Colorado Potato Beetle, Leptinotarsa decemlineata, is a major agricultural pest of solanaceous crops in the United States. Historically, a multitude of insecticides have been used to control problematic populations.
Justin Clements, Russell L Groves, JoAnn Cava, Caroline C Barry, Scott Chapman, Jake M Olson   +5 more
doaj   +1 more source

Linoleic acid-induced endothelial activation

Journal of Lipid Research, 2004
Hypertriglyceridemia, an important risk factor of atherosclerosis, is associated with increased circulating free fatty acids. Research to date indicates that linoleic acid (LA), the major fatty acid in the American diet, may be atherogenic by activating ...
Viswanathan Saraswathi, Guoyao Wu, Michal Toborek, Bernhard Hennig   +3 more
doaj   +1 more source

Mechanistic investigation of Liujing Toutong tablet in the treatment of cerebral ischemia–reperfusion injury in rats by the integration of serum pharmacochemistry and metabolomics

Animal Models and Experimental Medicine, EarlyView.
The research strategy for pharmacodynamics, serum pharmacochemistry, metabolomics, and network pharmacology analysis method in intervention effects of LTT are illustrated. Abstract Background Liujing Toutong tablet (LTT) is a traditional Chinese patent medicine.
Zihan Yu, Ke Pei, Xiulin Wang, Wenling Li, Hongchang Li, Wangyang Xie, Xianglong Meng, Tingting Zhao, Yan Ning, Haixin Liu, Wenbin He   +10 more
wiley   +1 more source

Isomerization increases the postprandial oxidation of linoleic acid but not α-linolenic acid in men

Journal of Lipid Research, 2001
Human lipid intake contains various amounts of trans fatty acids. Refined vegetable and frying oils, rich in linoleic acid and/or α-linolenic acid, are the main dietary sources of trans-18:2 and trans-18:3 fatty acids. The aim of the present study was to
L. Bretillon, J.M. Chardigny, J.L. Sébédio, J.P. Noël, C.M. Scrimgeour, C.E. Fernie, O. Loreau, P. Gachon, B. Beaufrère   +8 more
doaj   +1 more source

Potentiation of drug-induced cytotoxicity by conjugated linoleic acids (CLA) in in vitro models of drug-resistant cancer [PDF]

, 2009
Preclinical studies indicating that conjugated isomers of linoleic acid suppress mitosis, restore apoptosis, induce differentiation and suppress angiogenesis in animal models of cancer formed the rationale for an in vitro investigation of their potential
O'Reilly, Isobel
core