Results 71 to 80 of about 2,518,882 (259)

The effect of the dietary constituent conjugated linoleic acid and homocysteine on vascular endothelial cell function [PDF]

, 2004
The interaction between circulating dietary constituents and the vascular endothelial monolayer is vital to the proper maintenance o f vascular homeostatic mechanisms, such as vasoregulation. Endothelial dysfunction with subsequent loss of vasoregulatory
Coen, Paul Martin
core   +2 more sources

Metabolism of U13C-labeled linoleic acid in lactating women

Journal of Lipid Research, 1998
Long chain polyunsaturated fatty acids are nutritionally important constituents of breast milk. The origin of these fatty acids in milk has not been clearly identified.
H. Demmelmair, M. Baumheuer, B. Koletzko, K. Dokoupil, G. Kratl   +4 more
doaj   +1 more source

Optimization of preparation of conjugated linoleic acid by alkali isomerization of peanut oil

Shipin yu jixie, 2023
Objective: To obtain a promising production technique of conjugated linoleic acid (CLA). Methods: The alkali isomerization was used to prepare CLA from peanut oil.
SHEN Qiu-yun, PENG Qing-jing
doaj   +1 more source

In vitro study of dietary factors affecting the biohydrogenation shift from trans-11 to trans-10 fatty acids in the rumen of dairy cows [PDF]

, 2012
On the basis of the isomer-specific effects of trans fatty acids (FA) on human health, and the detrimental effect of t10,c12-conjugated linoleic acid (CLA) on cows’ milk fat production, there is a need to identify factors that affect the shift from trans-
Troegeler-Meynadier, Annabelle, A. Troegeler-Meynadier, A. Zened, Zened, Asma, Enjalbert, Francis, Nicot, Marie-Claude, F. Enjalbert, M.C. Nicot   +7 more
core   +1 more source

A Molecular Engineering Strategy to Fine‐Tune Phototoxicity of AIE Probes for Super‐Resolution Imaging of Mitochondrial Cristae Dynamics

Advanced Science, EarlyView.
Regulation of molecular packing, phototoxicity, and ROS output of AIE photosensitizers is achieved through carboxylation and alkyl‐chain‐length tuning. The probe designed via this strategy enables super‐resolution visualization of inner‐mitochondrial‐membrane cristae dynamics under controlled oxidative stress, and fluorescence‐lifetime imaging of ...
Kongqi Chen, Mengjie Wang, Chuen Kam, Zhiming Wang, Qinrong Zhang, Sijie Chen   +5 more
wiley   +1 more source

Starch plus sunflower oil addition to the diet of dry dairy cows results in a trans-11 to trans-10 shift of biohydrogenation [PDF]

, 2013
Trans fatty acids (FA), exhibit different biological properties. Among them, cis-9,trans-11 conjugated linoleic acid has some interesting putative health properties, whereas trans-10,cis-12 conjugated linoleic acid has negative effects on cow milk fat ...
Troegeler-Meynadier, Annabelle, Zened, Asma, Enjalbert, Francis, Nicot, Marie-Claude   +3 more
core   +1 more source

An Integrative Strategy Delineates Modular Metabolic Remodeling and Potential Therapeutic Targets Across Metabolic Diseases

Advanced Science, EarlyView.
An integrative single‐cell atlas across multiple metabolic diseases reveals coordinated metabolic modules and disease‐shared versus disease‐specific pathway activities. By systematically comparing scoring strategies, a robust RankAve framework is established. Coupled with network analysis and drug‐target prediction, this resource uncovers cross‐disease
Kuan Yang, Congxue Hu, Hang Zhao, Xiao Peng, Yiming Yan, Jiasi Wang, Wenqi Jiang, Depeng Mu, Yan Cao, Xia Li, Yunpeng Zhang   +10 more
wiley   +1 more source

Harnessing Large‐Scale Multi‐Omics Data for Risk Prediction and Deep Phenotyping of Valvular Heart Diseases in the General Population

Advanced Science, EarlyView.
Large‐scale UK Biobank analyses identify clinical and proteomic signatures for early prediction of valvular heart disease and its subtypes. Proteins add predictive value for VHD, AVS, and MVR, with outcome‐specific compact panels showing translational potential. Multi‐layer evidence highlights matrix remodeling, protease regulation, immune inflammation,
Zhihao Jiang, Yang Liu, Mingyu Song, Ning Chen, Canqing Yu, Jun Lv, Eric Yuk Fai Wan, Lu Qi, Liming Li, Dianjianyi Sun, Bang Zheng   +10 more
wiley   +1 more source

Dietary supplementation with conjugated linoleic acid plus n-3 polyunsatturated fatty acid increases food intake and brown adipose tissue in rats [PDF]

, 2009
Peer ...
Sharon Mitchell, Morris, Amanda C, D. Vernon Rayner, Klaus Wahle, Lynda Williams, Mitchell, Sharon E, Klaus W. Wahle, Wahle, Klaus W, Alan Sneddon, Williams, Lynda M, Jung-Heun Ha, Amanda C. Morris, Ha, Jung-Heun, Sneddon, Alan A, Alan A. Sneddon, Bashir, Shabina, Shabina Bashir, Amanda Morris, Sharon E. Mitchell, Lynda M. Williams, Rayner, D Vernon   +20 more
core   +1 more source

Multi‐Omics Profiling of High‐Grade Serous Ovarian Cancer Reveals an Inflammation‐Related Lipid Metabolism Subtype Associated With Platinum Resistance

Advanced Science, EarlyView.
Through integrated proteomic and metabolomic profiling, Zhao et al. identified three molecular subtypes of high‐grade serous ovarian cancer. The high‐risk subtype exhibits activated arachidonic acid metabolism and cyclooxygenase‐2 overexpression. This metabolic axis promotes M2‐like macrophage infiltration, which contributes to platinum resistance ...
Yuxi Zhao, Junyi Li, Bo Zheng, Wanshan Liu, Yaru Wang, Shufeng Wang, Ying Cui, Huiqin Guo, Hongxia Wang, Ting Xiao, Kun Qian, Jing Zuo   +11 more
wiley   +1 more source