Results 21 to 30 of about 895,121 (257)

Potentiation of drug-induced cytotoxicity by conjugated linoleic acids (CLA) in in vitro models of drug-resistant cancer [PDF]

, 2009
Preclinical studies indicating that conjugated isomers of linoleic acid suppress mitosis, restore apoptosis, induce differentiation and suppress angiogenesis in animal models of cancer formed the rationale for an in vitro investigation of their potential
O'Reilly, Isobel
core   +1 more source

Influence of dietary linoleic acid intake with different fat intakes on arachidonic acid concentrations in plasma and platelet lipids and eicosanoid biosynthesis in female volunteers [PDF]

, 2003
Background/Aim: N-6 fatty acids are considered to promote diseases prevalent in industrialized countries and characterized by an increased eicosanoid biosynthesis from arachidonic acid (AA).
Zöllner, N., Adam, Olaf, Wolfram, G.
core   +1 more source

Effects of conjugated linoleic acid on linoleic and linolenic acid metabolism in man [PDF]

British Journal of Nutrition, 2006
Evidence from animal studies suggests that conjugated linoleic acid (CLA) modulates plasma and tissue appearance of newly synthesized PUFA. The effects of a 1·2g (0·5% energy) daily intake of thecis-9,trans-11 (c9,t11) isomer of CLA,trans-10,cis-12 (t10,c12) isomer of CLA or olive oil (placebo) on linoleic acid (LA) and linolenic acid (LNA) metabolism ...
Anu M, Turpeinen, Sonja, Bärlund, Riitta, Freese, Peter, Lawrence, J Thomas, Brenna   +4 more
openaire   +2 more sources

Conjugated linoleic acid supplementation, insulin sensitivity, and lipoprotein metabolism in patients with type 2 diabetes mellitus. [PDF]

, 2004
BACKGROUND: Some animal studies have suggested that conjugated linoleic acid (CLA) supplementation may have therapeutic potential with respect to insulin sensitivity and lipid metabolism, which are important cardiovascular disease (CVD) risk factors ...
Mullen, Anne, Anne Mullen, John J Nolan, Moloney, F, Yeow, Toh-Peng, Toh-Peng Yeow, Helen M Roche, Yeow, TP, Roche, HM, Fiona Moloney, Mullen, A, Nolen, JJ, Moloney, Fiona, Nolan, John J, Roche, Helen M   +14 more
core   +1 more source

Oxidation of an oil rich in docosahexaenoic acid compared to linoleic acid in lactating women [PDF]

, 1999
Background: We studied the oxidation of an oil rich in docosahexaenoic acid (DHA; DHASCO(R)) in lactating mothers receiving a dietary DHA supplement or a placebo. The results were compared with the oxidation of linoleic acid.
Pohl, A., Sauerwald, T., Koletzko, Berthold, Fidler, N., Demmelmair, Hans   +4 more
core   +1 more source

Starch plus sunflower oil addition to the diet of dry dairy cows results in a trans-11 to trans-10 shift of biohydrogenation [PDF]

, 2013
Trans fatty acids (FA), exhibit different biological properties. Among them, cis-9,trans-11 conjugated linoleic acid has some interesting putative health properties, whereas trans-10,cis-12 conjugated linoleic acid has negative effects on cow milk fat ...
Troegeler-Meynadier, Annabelle, Zened, Asma, Enjalbert, Francis, Nicot, Marie-Claude   +3 more
core   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Inactivation of Enzymes by Linoleic Acid Hydroperoxides and Linoleic Acid

Agricultural and Biological Chemistry, 1970
The inactivation of the enzymes by linoleic acid hydroperoxides (LAHPO) was tested in connection with the toxicity of oxidized fat. At the same time, the inhibition of enzyme activities by linoleic acid was also tested. Ribonuclease (RNase), trypsin, chymotrypsin and pepsin which are considered to be simple proteins and not to be SH-enzymes were chosen
MATSUSHITA, Setsuro, KOBAYASHI, Masayo, NITTA, YUKI   +2 more
openaire   +1 more source

Effects of heating process of soybeans on ruminal production of conjugated linoleic acids and trans-octadecenoic acids in situ [PDF]

, 2006
The effects of two thermal treatments of soybeans, i.e. roasting (150˚C dry heat) and extrusion (140-150˚C), on conjugated linoleic acids (CLA) and trans-octadecenoic acids (trans-C18:1) productions obtained throughout ruminal C18:2 biohydrogenation in ...
Troegeler-Meynadier, Annabelle, Nicot, Marie-Claude, Enjalbert, Francis   +2 more
core   +1 more source

Probiotic bacteria produce conjugated linoleic acid locally in the gut that targets macrophage PPAR γ to suppress colitis. [PDF]

, 2012
Inflammatory bowel disease (IBD) therapies are modestly successful and associated with significant side effects. Thus, the investigation of novel approaches to prevent colitis is important.
Vogel, Hans, Christian Jobin (74703), Adria Carbo, Mireia Pedragosa, Jobin, Christian, Christian Jobin, Monica Viladomiu (120075), Carbo, Adria, Mireia Pedragosa (120080), Janelle C Arthur, Martin Storr (124415), Hans Vogel (182237), Benjamin A. Corl (182236), Hans Vogel, Viladomiu, Monica, Adria Carbo (120066), Arthur, Janelle C., Shaykhutdinov, Rustem, Pedragosa, Mireia, Storr, Martin, Raquel Hontecillas (120113), Bassaganya-Riera, Josep, De Simone, Claudio, Janelle C. Arthur (143340), Claudio De Simone (171437), Monica Viladomiu, Rustem Shaykhutdinov (182227), Rustem Shaykhutdinov, Martin Storr, Claudio De Simone, Josep Bassaganya-Riera (120051), Hontecillas, Raquel, Benjamin A Corl, Josep Bassaganya-Riera, Corl, Benjamin A., Raquel Hontecillas   +35 more
core   +2 more sources