Results 91 to 100 of about 406,174 (392)
Recent Advances in Lipase-Mediated Preparation of Pharmaceuticals and Their Intermediates
International Journal of Molecular Sciences, 2015 Biocatalysis offers an alternative approach to conventional chemical processes for the production of single-isomer chiral drugs. Lipases are one of the most used enzymes in the synthesis of enantiomerically pure intermediates.
Ana Caroline Lustosa de Melo Carvalho +7 more
semanticscholar +1 more source
The common truncation variant in pancreatic lipase related protein 2 (PNLIPRP2) is expressed poorly and does not alter risk for chronic pancreatitis [PDF]
, 2018 A nonsense variant (p.W358X) of human pancreatic lipase related protein 2 (PNLIPRP2) is present in different ethnic populations with a high allele frequency.
Hegyi, Eszter +7 more
core +2 more sources
Advanced Science, EarlyView.This study constructs a stacked multimodal machine learning model for nonalcoholic fattly liver disease (NAFLD) by integrating genetic and clinical features, and synthesize an in‐silico quantitative marker (ISNLD) that enables personalized risk stratification for intrahepatic and extrahepatic outcomes of high‐risk individuals of NAFLD.
Lushan Xiao +14 more
wiley +1 more source
Journal of Lipid Research, 2015 Adipocyte fatty acid binding protein 4, aP2, contributes to the pathogenesis of several common diseases including type 2 diabetes, atherosclerosis, fatty liver disease, asthma, and cancer.
Meric Erikci Ertunc +7 more
semanticscholar +1 more source
Assessment of Canine Pancreas-Specific Lipase and Outcomes in Dogs with Hemodialysis-Dependent Acute Kidney Injury. [PDF]
, 2018 BackgroundRenal replacement therapies can be life-saving for dogs with severe acute kidney injury (AKI), however, comorbidities including pancreatitis might affect outcome.Hypothesis/objectivesTo investigate the prevalence of pancreas-specific lipase ...
Cowgill, LD +3 more
core +2 more sources
Advanced Science, EarlyView.By studying the maturation mechanisms of vasopressin (AVP), this manuscript identifies FAM134B‐mediated ER‐phagy as a critical pathway for degrading both aggregated proAVP and the key ERAD component, HRD1. HRD1 induction mitigates proAVP aggregation and support AVP neuron function in the absence of autophagy.
Xuya Pan +16 more
wiley +1 more source
Medicinal Plants and Their Inhibitory Activities against Pancreatic Lipase: A Review
Evidence-Based Complementary and Alternative Medicine, 2015 Obesity is recognized as a major life style disorder especially in developing countries and it is prevailing at an alarming speed in new world countries due to fast food intake, industrialization, and reduction of physical activity.
A. Seyedan +4 more
semanticscholar +1 more source
Dydrogesterone and norethisterone regulate expression of lipoprotein lipase and hormones-sensitive lipase in human subcutaneous abdominal adipocytes [PDF]
, 2007 Aim: In premenopausal women, hyper-androgenicity is associated with central obesity and an increased cardiovascular risk. We investigated the effects of dydrogesterone (DYD)(a non-androgenic progestogen) and norethisterone (NET)(an androgenic progestogen)
Barnett, A. H. +5 more
core +1 more source
Engineered Tissue Models to Decode Host–Microbiota Interactions
Advanced Science, EarlyView.Host–Microbiota interactions in the human body. Created in BioRender. Ghezzi, C. (2025) https://BioRender.com/ihivskg. Abstract A mutualistic co‐evolution exists between the host and its associated microbiota in the human body. Bacteria establish ecological niches in various tissues of the body, locally influencing their physiology and functions, but ...
Miryam Adelfio +5 more
wiley +1 more source
Biochemistry, 2015 Lipase immobilization is frequently used for altering the catalytic properties of these industrially used enzymes. Many lipases bind strongly to hydrophobic surfaces where they undergo interfacial activation.
Themistoklis Zisis +5 more
semanticscholar +1 more source