Results 151 to 160 of about 130,112 (260)

White Adipose Tissue Browning and Cross Talk With Metabolic Diseases and Tumors: From Molecular Mechanisms to Clinical Translation

Med Research, EarlyView.
White adipose tissue undergoes browning under endogenous and exogenous stimuli, primarily regulated by core molecules such as PRDM16 and UCP1. It exhibits a double‐edged sword effect in metabolic diseases and tumors: while mitigating metabolic disease impacts and suppressing early‐stage tumors through nutritional competition, it may accelerate cachexia
Yingjiao Wang, Diyuan Zhang, Yuqin Zhou, Ling Qian, Yan Wang, Lei Peng, Min Zhao, Hao Tian, Zhenyu Wu, Aiqi Tang, Minghao Sun, Yi Zhang, Xiaowei Qi   +12 more
wiley   +1 more source

Lipase

Oleoscience
Kusum Chopra, Hiru Ranabhatt
openaire   +2 more sources

Genomic analysis of an extremophile PLS47 from a deep-sea vent. [PDF]

Front Microbiol
Furqan BRN, Widhiastuty MP, Febriani, Afifah DN, Iqbalsyah TM, Akhmaloka.   +5 more
europepmc   +1 more source

Uncovering the Complexity of Synucleinopathies: An Ongoing Tale Between Proteins and Lipids

Movement Disorders, EarlyView.
Abstract Neurodegenerative diseases are pathological states characterized by progressive alterations in brain homeostasis during aging. Synucleinopathies, including Parkinson's disease and dementia with Lewy bodies, are defined neuropathologically by the accumulation of inclusions known as Lewy bodies and Lewy neurites.
Manuel Flores‐León, Tiago F. Outeiro
wiley   +1 more source

Therapeutic Potential of Fecal Microbiota Transplantation for Male Sexual Dysfunction: Evidence and Clinical Perspectives

Microbiota Medicine Research, EarlyView.
ABSTRACT Fecal microbiota transplantation (FMT), a microbiome‐based therapy, shows potential in treating male sexual dysfunction. Research into the influence of FMT on male sexual function has recently garnered increasing attention. This review aims to explore the impact of FMT on male sexual function and the underlying mechanisms, and to analyze the ...
Junyi Chen, Chenfeng Bu, Xia Li, Lei Wu, Xingxiang He   +4 more
wiley   +1 more source

Addressing the distressing: Pancreatic enzyme replacement therapy mitigates abdominal symptoms and weight loss during chemotherapy for advanced pancreatic cancer: A prospective study

Nutrition in Clinical Practice, EarlyView.
Abstract Background Pancreatic enzyme insufficiency (PEI) contributes to symptom burden and malnutrition in advanced pancreatic cancer (aPC). We aimed to evaluate the impact of pancreatic enzyme replacement therapy (PERT) on symptom burden and weight during chemotherapy.
Pamela N. Klassen, Christina A. Kim, Jessica Kasnik, Michael B. Sawyer, Sunita Ghosh, Vickie Baracos, Vera C. Mazurak   +6 more
wiley   +1 more source

In vitro and in silico antiglycation antihyperglycemic and anti-inflammatory properties of chemically profiled fruit extracts of Solanum obtusifolium Dunal. [PDF]

Sci Rep
Abdnim R, Bouslamti M, El-Mernissi R, Farihi A, Chelouati T, Mahamat OB, Alyami EM, Bouallegue A, Khalid M, Almehizia AA, Zouirech O, Bnouham M.   +11 more
europepmc   +1 more source

Joint TOS/OMA/OAC Expert Guidance Statement on the Pharmacological Management of United States Adults With Overweight or Obesity Using the GRADE Approach

Obesity, EarlyView.
Guidance recommendations by TOS/OMA/OAC for the use of obesity medications to treat obesity and its complications. ABSTRACT Background Obesity affects over 40% of US adults, with severe obesity on the rise. Despite recognition of obesity as a chronic disease, it remains underdiagnosed and undertreated.
Lydia Alexander, Jonathan Q. Purnell, Karlijn Burridge, Marc‐André Cornier, Angela Golden, Deborah Bade Horn, Michelle Look, Joe Nadglowski, Camila Ávila‐Oliver, Francisco Novillo, Ana María Rojas‐Gómez, Brad Hussey, Ximena Ramos Salas   +12 more
wiley   +1 more source

Study of Microbial Communities in the Soda Lake of Isabel Island: Identification of Polyhydroxybutyrate (PHB) Degrading Enzymes. [PDF]

Environ Microbiol Rep
Hernández-Vázquez A, Garcia-Arellano H, González-Cervantes RM, López-Pérez M, Soto LMH, Meza JAC, Aguirre-Garrido JF.   +6 more
europepmc   +1 more source

Development of a Sustainable Biocatalytic Process for Geranyl Benzoate Production Using Immobilized Lipase

ChemistryOpen, EarlyView.
This study optimized solvent‐free geranyl benzoate production using Lipozyme 435, achieving 72% conversion in 6 hours. Open reactors improved yields (>99% in 48 hours) by removing inhibitorymethanol. Methyl benzoate reduced enzyme activity by 54%, though Lipura Flex showed better resistance. Human cell tests confirmed no cytotoxicity.
Domenico Meola, Chaimae Chaibi, Simona Aprile, Karina Cesca, Debora de Oliveira, Ariela Veloso de Paula, Francesco Presini, Federico Zappaterra, Pier Paolo Giovannini, Lindomar Alberto Lerin   +9 more
wiley   +1 more source