Novel approaches for drug development against chronic primary pain: A systematic review
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus +5 more
wiley +1 more source
Biodegradation of polyethylene terephthalate microplastics by Paenibacillus naphthalenovorans PETKKU2: Response surface optimization and genomic evidence for an alternative degradation mechanism. [PDF]
Choonut A +7 more
europepmc +1 more source
Covalent fluorescent probes for 2‐arachidonoylglycerol metabolic pathways
Abstract Covalent fluorescent probes have emerged as versatile chemical tools to visualise active enzymes in complex biological systems. When tailored for specific applications, ranging from activity‐based protein profiling for drug development to high spatiotemporal resolution imaging of enzymatic activities, these probes provide unique insights into ...
Nick D. F. Puijmbroeck +1 more
wiley +1 more source
Diagnostic Utility of Urinary Amylase in Acute Pancreatitis: A Systematic Review. [PDF]
Ullah U +3 more
europepmc +1 more source
Supplementation with commercially available probiotic bacterial strains reduces fat accumulation in <i>Caenorhabditis elegans</i> by regulating the lipid metabolism pathway. [PDF]
Saito R +3 more
europepmc +1 more source
Safety evaluation of the food enzyme triacylglycerol lipase from the genetically modified <i>Aspergillus oryzae</i> strain NZYM-PH. [PDF]
EFSA Panel on Food Enzymes (FEZ) +17 more
europepmc +1 more source
Multispecialty Management of Pancreaticopleural Fistula With Recurrent Pleural Effusions: A Case Report and Literature Review. [PDF]
Prasad N, Bijjam R, Kathi PR, Mittal V.
europepmc +1 more source
Comparative Transcriptomics Reveals the Molecular Basis for Inducer-Dependent Efficiency in Gastrodin Propionylation by <i>Aspergillus oryzae</i> Whole-Cell Biocatalyst. [PDF]
Wu D, Ma M, Liu X, Li X, Zhao G.
europepmc +1 more source

