Results 51 to 60 of about 134,089 (267)

Enhanced Antibacterial Properties of Lyotropic Liquid Crystalline Nanoparticles via Curvature Modulation

open access: yesAdvanced Science, EarlyView.
Lipid nanostructured particles with increasing negative Gaussian curvature progress from vesicles to P‐cubosomes and D‐cubosomes. This curvature hierarchy enhances interaction with bacterial membranes, promotes membrane remodeling and leakage, and potentiates daptomycin activity against MRSA.
Xiangfeng Lai   +10 more
wiley   +1 more source

Current Challenges of Transcription Compartmentalization Research

open access: yesAdvanced Science, EarlyView.
Transcription factors, coactivators, and RNA polymerase II assemble into transcription compartments ranging from small, defined complexes to liquid‐like condensates. This review unifies these seemingly competing descriptions along a single continuum and asks what these compartments have been shown to do, and what they have not, revealing that the most ...
Thomas Quail, Sina Wittmann
wiley   +1 more source

ANGPTL4 Exacerbates Renal Injury in Diabetic Kidney Disease by Impairing Podocyte Lipophagy via Compromised Lysosomal Degradative Function

open access: yesAdvanced Science, EarlyView.
In diabetic kidney disease, elevated podocyte ANGPTL4 is linked to reduced TFEB nuclear localization and compromised lysosomal degradative function. These changes impair podocyte lipophagy and promote lipid‐droplet accumulation and podocyte injury, which may contribute to renal injury progression.
Xiaojing Liu   +7 more
wiley   +1 more source

Inhibition of lipase activities by basic polysaccharide

open access: yesJournal of Lipid Research, 2007
Basic polysaccharide strongly inhibited the hydrolysis of trioleoylglycerol (TO) emulsified with phosphatidylcholine and taurocholate by either pancreatic lipase or carboxylester lipase.
Takahiro Tsujita   +5 more
doaj   +1 more source

Genotype–Phenotype Correlations of Monoallelic PFIC Variants in Pediatric Liver Disease: A Multicenter Retrospective Cohort Study

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Progressive familial intrahepatic cholestasis (PFIC) is classically caused by biallelic pathogenic variants, yet monoallelic variants of uncertain significance (VUS) in PFIC‐associated genes are increasingly identified in children with cholestasis, creating diagnostic uncertainty.
Brett J. Hoskins   +9 more
wiley   +1 more source

Measurement of two plasma triglyceride lipases by an immunochemical method: studies in patients with hypertriglyceridemia

open access: yesJournal of Lipid Research, 1976
Postheparin plasma lipolytic activity consists of two hydrolytic activities, hepatic triglyceride lipase and lipoprotein lipase. These two enzymes were separated and partially purified by means of ammonium sulfate precipitation and affinity ...
H Greten   +5 more
doaj   +1 more source

Photochemisch erzeugte Oxetane als Schlüssel zur endergonen Cyclopropansynthese

open access: yesAngewandte Chemie, EarlyView.
Eine neuartige Oxetan‐zu‐Cyclopropan‐Umlagerung eröffnet einen atomökonomischen Zugang zu dicht funktionalisierten Cyclopropanen aus Furanen und photochemisch aktivierten Aldehyden. Die erhaltenen Strukturen erschließen komplexe bioaktive Motive und fungieren als vielseitige Plattform für die asymmetrische Cyclopropansynthese.
Tim Köglmeier   +2 more
wiley   +1 more source

Immobilization of Isolated Lipase From Moldy Copra (Aspergillus Oryzae)

open access: yesE-Journal of Chemistry, 2011
Enzyme immobilization is a recovery technique that has been studied in several years, using support as a media to help enzyme dissolutions to the reaction substrate.
Seniwati Dali   +4 more
doaj   +1 more source

PARTIAL CHARACTERIZATION of lipase from COCOA BEANS (Theobroma cacao. L.) of clone PBC 159

open access: yesIndonesian Journal of Chemistry, 2010
A study was carried out to characterize the cocoa lipase from cocoa beans (Theobroma cacao, L.) of clone PBC 159. The optimum temperature of cocoa lipase was 30-40 °C and the pH optimum was 7.0-8.0.
Ratna Agung Samsumaharto
doaj   +1 more source

Optimization of lipase entrapment in alginate gel bead for palm olein hydrolysis [PDF]

open access: yesSongklanakarin Journal of Science and Technology (SJST), 2007
Lipase from Pseudomonas sp. was entrapped by drop-wise addition of an aqueous mixture of alginate and the biocatalyst to hardening solution of CaCl2 for the purpose of palm olein hydrolysis.
Cheirsilp, B.   +2 more
doaj  

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