Results 61 to 70 of about 130,112 (260)

The NADPH oxidase NOX4 regulates redox and metabolic homeostasis preventing HCC progression

Hepatology, EarlyView., 2022
Loss of NOX4 in HCC tumor cells induces metabolic reprogramming in a Nrf2/MYC‐dependent manner to promote HCC progression. Abstract Background and Aims The NADPH oxidase NOX4 plays a tumor‐suppressor function in HCC. Silencing NOX4 confers higher proliferative and migratory capacity to HCC cells and increases their in vivo tumorigenic potential in ...
Irene Peñuelas‐Haro, Rut Espinosa‐Sotelo, Eva Crosas‐Molist, Macarena Herranz‐Itúrbide, Daniel Caballero‐Díaz, Ania Alay, Xavier Solé, Emilio Ramos, Teresa Serrano, María L. Martínez‐Chantar, Ulla G. Knaus, José M. Cuezva, Antonio Zorzano, Esther Bertran, Isabel Fabregat   +14 more
wiley   +1 more source

Immobilization of Isolated Lipase From Moldy Copra (Aspergillus Oryzae)

E-Journal of Chemistry, 2011
Enzyme immobilization is a recovery technique that has been studied in several years, using support as a media to help enzyme dissolutions to the reaction substrate.
Seniwati Dali, A. B. D. Rauf Patong, M. Noor Jalaluddin, Pirman, Baharuddin Hamzah   +4 more
doaj   +1 more source

PARTIAL CHARACTERIZATION of lipase from COCOA BEANS (Theobroma cacao. L.) of clone PBC 159

Indonesian Journal of Chemistry, 2010
A study was carried out to characterize the cocoa lipase from cocoa beans (Theobroma cacao, L.) of clone PBC 159. The optimum temperature of cocoa lipase was 30-40 °C and the pH optimum was 7.0-8.0.
Ratna Agung Samsumaharto
doaj   +1 more source

PIK3CA Mutations Downregulate PPT1 to Promote Adipogenesis by Suppressing P300 Depalmitoylation and Phase Separation

Advanced Science, EarlyView.
This study demonstrates that somatic PIK3CA mutations suppress PPT1 expression via activation of the PI3K–AKT–c‐JUN axis. This reduction in PPT1 weakens its interaction with P300, thereby increasing palmitoylation at C1176 of P300 and protecting P300 from lysosomal degradation.
Hongrui Chen, Zening Huang, Rui Chang, Wei Gao, Yajing Qiu, Bin Sun, Chen Hua, Xiaoxi Lin   +7 more
wiley   +1 more source

Loss of hepatic SMLR1 causes hepatosteatosis and protects against atherosclerosis due to decreased hepatic VLDL secretion

Hepatology, EarlyView., 2022
The role of SMLR1 in lipid metabolism (high fat + cholesterol diet in mice) Abstract Background and Aims The assembly and secretion of VLDL from the liver, a pathway that affects hepatic and plasma lipids, remains incompletely understood. We set out to identify players in the VLDL biogenesis pathway by identifying genes that are co‐expressed with the ...
Willemien van Zwol, Antoine Rimbert, Justina C. Wolters, Marieke Smit, Vincent W. Bloks, Niels J. Kloosterhuis, Nicolette C. A. Huijkman, Mirjam H. Koster, Umesh Tharehalli, Simon M. de Neck, Colin Bournez, Marceline M. Fuh, Jeroen Kuipers, Sujith Rajan, Alain de Bruin, Henry N. Ginsberg, Gerard J. P. van Westen, M. Mahmood Hussain, Ludger Scheja, Joerg Heeren, Philip Zimmerman, Bart van de Sluis, Jan Albert Kuivenhoven   +22 more
wiley   +1 more source

HIDROLISIS ENZIMATIS STEARIN SAWIT MENJADI MONOGLISERIDA OLEH LIPASE DARI Rhizomucor miehei DAN PANKREAS (Enzymatic Hydrolysis of Palm Stearin to Produce Monoglyceride by Lipase from Rhizomucor miehei and Pancreatic)

Agritech, 2013
The objectives of the research were to evaluate the effect of the pH, ratio of substrate:phospate buffer, and reaction time on the enzymatic hydrolysis of palm stearin to obtain monoglyceride by R. miehei and pancreatic lipases.
Steivie Karaouw, Suparmo Suparmo, Pudji Hastuti, Tyas Utami   +3 more
doaj   +1 more source

Immobilization of Lipase from Thermomyces Lanuginosus and Its Glycerolysis Ability in Diacylglycerol Preparation

Molecules
In the glycerolysis process for diacylglycerol (DAG) preparation, free lipases suffer from poor stability and the inability to be reused. To address this, a cost-effective immobilized lipase preparation was developed by cross-linking macroporous resin ...
Rui Xie, Yee-Ying Lee, Pengkai Xie, Chin-Ping Tan, Yong Wang, Zhen Zhang   +5 more
doaj   +1 more source

A rare entity in ED: Normal lipase level in acute pancreatitis

Turkish Journal of Emergency Medicine, 2016
Acute pancreatitis can have a variable presentation and diagnosis is based on clinical presentation, serum amylase and lipase levels and computed tomography.
Onder Limon, Erkan Sahin, Funda Ugur Kantar, Deniz Oray, Asli Aydinoglu Ugurhan   +4 more
doaj   +1 more source

Hepatic triacylglycerol lipase activities after induction of diabetes and administration of insulin or glucagon.

Journal of Lipid Research, 1982
Triacylglycerol lipase activities of homogenates and subcellular fractions of rat liver were measured under optimal conditions at pH 7.5 using emulsified tri[1-14C]oleoylglycerol as substrate.
T E Knauer, J A Woods, R G Lamb, H J Fallon   +3 more
doaj   +1 more source

OPTIMASI KONDISI PURIFIKASI PARSIAL LIPASE Aspergillus niger 65I6 SOLID STATE FERMENTATION (SSF) PADA MEDIUM BUNGKIL JARAK SEBAGAI SUMBER BELAJAR PENGANTAR MIKROBIOLOGI

Bioedukasi: Jurnal Pendidikan Biologi FKIP UM Metro, 2012
Extracellular lipase is an enzyme that catalyzes the hydrolysis reaction of triglycerides into free fatty acids and glycerol and synthesis reaction of esters. Lipase can be produced by microbes include bacteria, fungi and yeasts.
Maulina Nurikasari
doaj   +1 more source