Results 1 to 10 of about 1,333,166 (267)

Overexpression of SCAP inhibits autophagy and promotes lipid accumulation in vascular smooth muscle cells

Di-san junyi daxue xuebao, 2022
Objective To determine the effect of sterol regulatory element binding proteins cleavage activating protein (SCAP) on foam cell formation in vascular smooth muscle cells (VSMCs). Methods LV-SCAP were constructed with LV-SCAP, and LV-Control group served
RAO Yuhan, LI Danyang, HOU Xiaoli, YAO Yincheng, SU Yu   +4 more
doaj   +1 more source

Long chain ceramides raise the main phase transition of monounsaturated phospholipids to physiological temperature

Scientific Reports, 2022
Little is known about the molecular mechanisms of ceramide-mediated cellular signaling. We examined the effects of palmitoyl ceramide (C16-ceramide) and stearoyl ceramide (C18-ceramide) on the phase behavior of 1-palmitoyl-2-oleoyl-sn-glycero-3 ...
Hiroshi Takahashi, Tomohiro Hayakawa, Asami Makino, Kunihiko Iwamoto, Kazuki Ito, Satoshi B. Sato, Toshihide Kobayashi   +6 more
doaj   +1 more source

Lipid Nanotechnology [PDF]

International Journal of Molecular Sciences, 2013
Nanotechnology is a multidisciplinary field that covers a vast and diverse array of devices and machines derived from engineering, physics, materials science, chemistry and biology. These devices have found applications in biomedical sciences, such as targeted drug delivery, bio-imaging, sensing and diagnosis of pathologies at early stages.
S. Mashaghi (Samaneh), T. Jadidi, G.H. Koenderink (Gijsje), A. Mashaghi (Alireza)   +3 more
openaire   +4 more sources

9-cis and all-trans beta-carotene isomers of super critical CO2-extracted Dunaliella oil are absorbed and accumulated in mouse tissues

Applied Phycology, 2021
Animals cannot produce β-carotene, and therefore they exclusively depend on its dietary availability. We previously showed that a 9-cis β-carotene-enriched diet, provided as Dunaliella powder, has a beneficial effect on atherosclerosis and diabetes ...
Shahar Delman, Mika Anekstein, Arnon Afek, Rachel Twitto-Greenberg, Dror Harats, Reut Shnerb Ganor, Ayelet Harari, Aviv Shaish   +7 more
doaj   +1 more source

Effects of age, gender, and menopausal status on plasma low density lipoprotein cholesterol and apolipoprotein B levels in the Framingham Offspring Study.

Journal of Lipid Research, 1994
Plasma low density lipoprotein (LDL) cholesterol, non-high density lipoprotein (HDL) cholesterol, and apolipoprotein (apo) B, the major protein constituent of LDL, were measured in 1,533 men (mean age 49 +/- 10 years) and 1,597 women (mean age 49 +/- 10 ...
E J Schaefer, S Lamon-Fava, S D Cohn, M M Schaefer, J M Ordovas, W P Castelli, P W Wilson   +6 more
doaj   +1 more source

Factors associated with low and elevated plasma high density lipoprotein cholesterol and apolipoprotein A-I levels in the Framingham Offspring Study.

Journal of Lipid Research, 1994
A decreased high density lipoprotein (HDL) cholesterol level (< 35 mg/dl) has been shown to be a significant independent risk factor for coronary heart disease (CHD).
E J Schaefer, S Lamon-Fava, J M Ordovas, S D Cohn, M M Schaefer, W P Castelli, P W Wilson   +6 more
doaj   +1 more source

The association of soluble cluster of differentiation 36 with metabolic diseases: A potential biomarker and therapeutic target

Pediatric Discovery, 2023
A cluster of differentiation 36 (CD36), also known as fatty acid translocase, plays an important role in developing and progressing metabolic diseases. Soluble CD36 (sCD36), a circulating form of CD36, is identified in human plasma.
Yun Li, Yaxi Chen, Xiong Z. Ruan
doaj   +1 more source

Photoswitchable phospholipid FRET acceptor: Detergent free intermembrane transfer assay of fluorescent lipid analogs

Scientific Reports, 2017
We have developed and characterized a novel photoswitchable phospholipid analog termed N-nitroBIPS-DPPG. The fluorescence can be switched on and off repeatedly with minimal photobleaching by UV or visible light exposure, respectively.
Mariko Sumi, Asami Makino, Takehiko Inaba, Yasushi Sako, Fumihiro Fujimori, Peter Greimel, Toshihide Kobayashi   +6 more
doaj   +1 more source

cDNA cloning of carboxyl ester lipase from human pancreas reveals a unique proline-rich repeat unit.

Journal of Lipid Research, 1991
We report the isolation and nucleotide sequence of the cDNA for carboxyl ester lipase (CEL) from human pancreas. CEL was purified from human pancreas and microsequence analysis was performed on the amino-terminal and internal peptides.
K Reue, J Zambaux, H Wong, G Lee, TH Leete, M Ronk, JE Shively, B Sternby, B Borgström, D Ameis   +9 more
doaj   +1 more source

Trp64—-nonsense mutation in the lipoprotein lipase gene.

Journal of Lipid Research, 1992
A lipoprotein lipase (LpL) gene defect has been identified, a G—-A transition at nucleotide position 446 of exon 3, resulting in a premature termination codon (Trp—-stop) at amino acid residue 64.
D L Sprecher, J Kobayashi, M Rymaszewski, IJ Goldberg, BV Harris, PS Bellet, D Ameis, R L Yunker, DM Black, EA Stein   +9 more
doaj   +1 more source