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Lipid-Based Nanoparticles: SLN, NLC, and MAD
2019Lipid-based nanosystems have been widely proposed as novel drug carrier systems since they have gained interest as matrixes able to dissolve and to control the delivery of active molecules, on one hand improving their solubility in water and their bioavailability and on the other reducing side-effects.
R. Cortesi +3 more
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Lipid-Based Nanoparticles as Carriers for Dermal Delivery of Antioxidants
Current Drug Metabolism, 2017The skin, being the outermost layer of our body, is constantly exposed to oxidative stress induced by UV-radiation, pollutants, smoke and xenobiotics. To counteract the deleterious effects of such exposure, the skin is equipped with a complex anti-oxidation system, involving both exogenous and endogenous antioxidants.
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Development and characterization of the voriconazole loaded lipid-based nanoparticles
Journal of Pharmaceutical and Biomedical Analysis, 2017The number of topical fungal infections is growing, mostly owing to immunosuppressive therapy. Several topical fungal infections, such as eye mycoses, can be treated by local administration of antimycotic drugs. One major group of the antifungal agents is triazole, such as voriconazole (VCZ), which is used as the first line treatment of aspergillosis ...
Petra Füredi +6 more
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Lipid-Based Nanoparticles for Vaccine Applications
2015Currently available vaccine adjuvants are ineffective against a wide range of infectious pathogens as well as cancers. Therefore, there is a critical demand for new vaccine strategies that can elicit potent cellular and humoral immune responses. Liposomes have been widely examined as vaccine delivery systems because of their safety, low toxicity, and ...
Rui Kuai +3 more
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Lipid-based nanoparticles for drug delivery
Lipid-based nanoparticles represent a promising strategy for the delivery of therapeutics, offering potential treatment avenues for various diseases. The thesis aimed to explore two examples of lipid-based nanoparticle systems, focusing on their efficacy, safety, and stability to evaluate their suitability for future clinical use.Mahmoud, Mahmoud Sayed Hanafy +1 more
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Lipid-Based Nanoparticles as Nonviral Gene Delivery Vectors
2013Efficient delivery of nucleic acids into cells is a promising technique to modulate cellular gene expression for therapeutic and research applications. Cationic lipid-based liposomes represent one of the most intensively studied and employed nonviral vectors.
D. Pezzoli +3 more
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Lipid Nanoparticles for Drug Delivery
Advanced NanoBiomed Research, 2022Letao Xu, Chun-Xia Zhao, Guangze Yang
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The role of lipid components in lipid nanoparticles for vaccines and gene therapy
Advanced Drug Delivery Reviews, 2022Jayesh A Kulkarni +2 more
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