Results 11 to 20 of about 1,664,116 (319)
Lipid A and Anti-Lipid A [PDF]
Infection and Immunity, 1979 Lipid A in free form, in crude antigen preparations, and on Formalin-treated Escherichia coli and Salmonella minnesota R595 was employed in studies of its antigenic composition, immunogenicity, and availability on gram-negative bacteria.
I, Mattsby-Baltzer, B, Kaijser
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Imaging of Lipid Biosynthesis: How a Neutral Lipid Enters Lipid Droplets [PDF]
Traffic, 2007 The biosynthesis and storage of triglyceride (TG) is an important cellular process conserved from yeast to man. Most mammalian cells accumulate TG in lipid droplets, most prominent in adipocytes, which are specialized to store large amounts of the TG over long periods. In this study, we followed TG biosynthesis and targeting by fluorescence imaging in
Kuerschner L., Moessinger C., Thiele, C.
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Lipid Simulations: A Perspective on Lipids in Action [PDF]
Cold Spring Harbor Perspectives in Biology, 2011 In this article, we provide an overview of lipid simulations, describing how a computer can be used as a laboratory for lipid research. We briefly discuss the methodology of lipid simulations followed by a number of topical applications that show the benefit of computer modeling for complementing experiments. In particular, we show examples of cases in
Vattulainen Ilpo, Rog Thomasz
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Analytical Biochemistry, 2008 Lipopolysaccharide (LPS), a major component of the outer membranes of gram-negative bacteria, is composed of a polysaccharide chain attached to a lipid A base that contains a disaccharide headgroup with two negative phosphate groups and at least four acyl chains.
Lynn E, Bretscher +2 more
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A lipid transfer protein that transfers lipid [PDF]
The Journal of Cell Biology, 2007 Very few lipid transfer proteins (LTPs) have been caught in the act of transferring lipids in vivo from a donor membrane to an acceptor membrane. Now, two studies (Halter, D., S. Neumann, S.M. van Dijk, J. Wolthoorn, A.M. de Maziere, O.V. Vieira, P. Mattjus, J. Klumperman, G. van Meer, and H. Sprong. 2007. J. Cell Biol.
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Microorganisms, 2021 Genome sequence comparisons to infer likely gene functions require accurate ortholog assignments. In Pseudomonas spp., the sensor-regulator ColS-ColR two-component regulatory system responds to zinc and other metals to control certain membrane-related ...
Valley Stewart, Pamela C. Ronald
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Flazin as a Lipid Droplet Regulator against Lipid Disorders
Nutrients, 2022 Lipid disorders are closely related to numerous metabolic diseases, and lipid droplets (LDs) have been considered as a new target for regulating lipid metabolism. Dietary intervention and nutraceuticals provide safe and long-term beneficial effects for treating metabolic diseases.
Xunzhi Wu +7 more
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The Serine Hydrolase ABHD6 Is a Critical Regulator of the Metabolic Syndrome
Cell Reports, 2013 The serine hydrolase α/β hydrolase domain 6 (ABHD6) has recently been implicated as a key lipase for the endocannabinoid 2-arachidonylglycerol (2-AG) in the brain.
Gwynneth Thomas +25 more
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Heliyon, 2023 Toll-like receptor (TLR) agonists are recognized as potential immune-enhancing adjuvants and are included in several licensed vaccines. Monophosphoryl lipid A (MPL®, GlaxoSmithKline) is one such TLR4 agonist that has been approved for use in human ...
Gang Hu +7 more
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CGI-58/ABHD5 is phosphorylated on Ser239 by protein kinase A: control of subcellular localization[S]
Journal of Lipid Research, 2015 CGI-58/ABHD5 coactivates adipose triglyceride lipase (ATGL). In adipocytes, CGI-58 binds to perilipin 1A on lipid droplets under basal conditions, preventing interaction with ATGL. Upon activation of protein kinase A (PKA), perilipin 1A is phosphorylated
Anita Sahu-Osen +13 more
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