Results 101 to 110 of about 2,038,928 (302)
Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells
FEBS Letters, EarlyView.DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park +8 more
wiley +1 more source
Growth kinetics and lipid accumulation in Rhodosporidium toruloides [PDF]
, 2010 The current interest in oleaginous yeasts as a viable source for microbial oil production has led to increasing research in understanding the growth conditions and kinetics of oleaginous yeasts with the aim to optimise productivity. Microbial oils can be
Trzcinski, Antoine
core
Clusterin deficiency induces lipid accumulation and tissue damage in kidney
, 2018 Clusterin is a secretory glycoprotein that is involved in multiple physiopathological processes, including lipid metabolism. Previous studies have shown that clusterin prevents hepatic lipid accumulation via suppression of sterol regulatory element ...
Young Kyung Bae +12 more
core +1 more source
Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy
FEBS Letters, EarlyView.The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley +1 more source
Lipid accumulation mediated by adiponectin in C2C12 myogenesis
BMB Reports, 2009 Plasma concentrations of adiponectin have been shown to be decreased in patients with obesity, cardiovascular diseases, hypertension and metabolic syndrome. Recent studies have found that adiponectin reduces lipid accumulation in macrophage foam cells which may impact the development of atherosclerosis.
Changjun, Yin +8 more
openaire +3 more sources
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Myocardial lipid accumulation and lipotoxicity in heart failure [PDF]
Journal of Lipid Research, 2009 The syndrome of chronic heart failure is a systemic disease state with primary cardiac dysfunction that subsequently affects multiple organ systems. After the primary cardiac insult, the clinical course of the patient is affected by comorbidities and the underlying type of cardiomyopathy.
openaire +2 more sources
Role of transcription factors in storage lipid accumulation in plants
, 2012 With few exceptions, seeds oil accumulates as triacylglycerols; three fatty acid molecules esterified to a glycerol backbone. The synthesis of normal fatty acids and unusual fatty acids, their assembly into triacylglycerols and subsequent packaging to ...
Fobert, Pierre R.
core +1 more source
Regulation of starch and lipid accumulation in a microalga Chlorella sorokiniana
, 2015 •We clearly describes accumulation patterns of starch and lipids.•Accumulation of starch and lipids depends on nitrogen status.•The biosynthesis of starch and lipids benefits from active photosynthetic activity.•Lipid synthesis is largely dependent on ...
Park, Jeong-Jin +17 more
core +1 more source
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source