Results 91 to 100 of about 1,939,990 (302)

Association between lipid accumulation products and stress urinary incontinence: a cross-sectional study from NHANES 2005 to 2018

Lipids in Health and Disease
Background Stress urinary incontinence (SUI), a common disorder of the pelvic floor, often results in anxiety, poor quality of life, and psychological issues among its sufferers.
JiHang Li, Dong Wang, Hu Tian, JianKun Yang, Hui Xia, WenBin Guo   +5 more
doaj   +1 more source

Choline supplementation prevents diet induced gut mucosa lipid accumulation in post-smolt Atlantic salmon (Salmo salar L.)

BMC Veterinary Research, 2020
Background Various intestinal morphological alterations have been reported in cultured fish fed diets with high contents of plant ingredients. Since 2000, salmon farmers have reported symptoms indicating an intestinal problem, which we suggest calling ...
Anne Kristine G. Hansen, Trond M. Kortner, Aleksei Krasnov, Ingemar Björkhem, Michael Penn, Åshild Krogdahl   +5 more
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Neutrophils Promote Metabolic Dysfunction‐Associated Steatotic Liver Disease Through Extracellular Vesicle‐mediated Lipid Transfer

Journal of Extracellular Vesicles
Metabolic dysfunction‐associated steatotic liver disease (MASLD) and metabolic dysfunction‐associated steatohepatitis are leading causes of chronic liver disease, yet the contribution of neutrophils to early hepatocellular lipid accumulation remains ...
Sanjeeb Shrestha, Soo‐Jung Jung, Seong‐Min Lim, Yu‐Bin Lee, Hyeung‐Wook Shin, Hoyul Lee, Hee‐Kyung Jin, Jae‐Sung Bae, Jae‐Han Jeon, Lai Guan Ng, Chang‐Won Hong   +10 more
doaj   +1 more source

Lipid Metabolism in Metabolic-Associated Steatotic Liver Disease (MASLD)

, 2023
Metabolic-associated steatotic liver disease (MASLD) is a cluster of pathological conditions primarily developed due to the accumulation of ectopic fat in the hepatocytes. During the severe form of the disease, i.e., metabolic-associated steatohepatitis (
Majid Mufaqam Syed-Abdul
core   +1 more source

Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers

FEBS Letters, EarlyView.
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui, Agnes Banreti, Armelle L. Ernst, Guillaume Leseigneur, Uwe J. Meierhenrich   +4 more
wiley   +1 more source

Lipid accumulation mediated by adiponectin in C2C12 myogenesis

BMB Reports, 2009
Plasma concentrations of adiponectin have been shown to be decreased in patients with obesity, cardiovascular diseases, hypertension and metabolic syndrome. Recent studies have found that adiponectin reduces lipid accumulation in macrophage foam cells which may impact the development of atherosclerosis.
Changjun, Yin, Qinqiang, Long, Ting, Lei, Xiaodong, Chen, Huan, Long, Bin, Feng, Yin, Peng, Yanling, Wu, Zaiqing, Yang   +8 more
openaire   +3 more sources

Hepatic lipid accumulation induced by a high-fat diet is regulated by Nrf2 through multiple pathways

, 2022
Nuclear factor erythroid 2-related factor 2 (Nrf2) is reportedly involved in hepatic lipid metabolism, but the results are contradictory, and the underlying mechanism remains unclear.
Wang, Miao, Chen, Chen, Li, Ling, Zheng, Hongting, Liang, Zerong, Yang, Gangyi, Yang, Mengliu, Zhu, Zhiming, Wu, Qinan, Qiu, Sheng   +9 more
core   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

FEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux, Christian Lévêque, Fodil Azzaz, Marion Sangiardi, Sarosh R Irani, Michael Seagar, Jacques Fantini, Oussama El Far   +7 more
wiley   +1 more source

Myocardial lipid accumulation and lipotoxicity in heart failure [PDF]

Journal of Lipid Research, 2009
The syndrome of chronic heart failure is a systemic disease state with primary cardiac dysfunction that subsequently affects multiple organ systems. After the primary cardiac insult, the clinical course of the patient is affected by comorbidities and the underlying type of cardiomyopathy.
openaire   +2 more sources