Results 91 to 100 of about 2,038,928 (302)

Do GLP-1 receptor agonists improve insulin sensitivity and reduce lipid accumulation in skeletal muscles and the liver independent of weight loss?

Endokrynologia Polska
Increased body mass index and excessive lipid accumulation are associated with enhanced production of toxic lipid species and impairedoxidation of free fatty acids (FFAs), a phenomenon defined as lipotoxicity.
Adrian Kołakowski, Monika Karczewska-Kupczewska   +1 more
doaj   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Association between lipid accumulation products and stress urinary incontinence: a cross-sectional study from NHANES 2005 to 2018

Lipids in Health and Disease
Background Stress urinary incontinence (SUI), a common disorder of the pelvic floor, often results in anxiety, poor quality of life, and psychological issues among its sufferers.
JiHang Li, Dong Wang, Hu Tian, JianKun Yang, Hui Xia, WenBin Guo   +5 more
doaj   +1 more source

Smaller is better: nanobodies meet NMR

FEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Calcium deposits in the perineurium and their relation to lipid accumulation

Journal of the Neurological Sciences, 1979
Calcification of the perineurium in sural nerves occurs in human adults. Deposits of calcium salts can be found focally in the middle and outer layers of the perineurium. Evidence indicates that this calcification is related to nerve fibre breakdown and to the local presence of lipids in the perineurium.
Lis, J.M.J. van, Jennekens, F.G.I., Veldman, H.   +2 more
openaire   +3 more sources

Choline supplementation prevents diet induced gut mucosa lipid accumulation in post-smolt Atlantic salmon (Salmo salar L.)

BMC Veterinary Research, 2020
Background Various intestinal morphological alterations have been reported in cultured fish fed diets with high contents of plant ingredients. Since 2000, salmon farmers have reported symptoms indicating an intestinal problem, which we suggest calling ...
Anne Kristine G. Hansen, Trond M. Kortner, Aleksei Krasnov, Ingemar Björkhem, Michael Penn, Åshild Krogdahl   +5 more
doaj   +1 more source

Model: Mycobacteria utilizes YY1-PRMT5 axis to repress ITCH and facilitate lipid accumulation.

, 2022
Model: Mycobacteria utilizes YY1-PRMT5 axis to repress ITCH and facilitate lipid accumulation.
Salik Miskat Borbora (9381455), Raju S. Rajmani (11134060), Kithiganahalli Narayanaswamy Balaji (9381464)   +2 more
core   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

FEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Theaflavins Attenuate Hepatic Lipid Accumulation through Activating Ampk in Human Hepg2 Cells

, 2008
Black tea is one of the world's most popular beverages, and its health- promoting effects have been intensively investigated. The antiobesity and hypolipidemic effects of black tea have attracted increasing interest, but the mechanisms underlying these ...
Lin, Chih-Li; Huang, Hsiu-Chen; Lin, Jen-Kun, 林志立;林仁混   +1 more
core  

Lipoprotein Lipase Regulates Microglial Lipid Droplet Accumulation

, 2021
Microglia become increasingly dysfunctional with aging and contribute to the onset of neurodegenerative disease (NDs) through defective phagocytosis, attenuated cholesterol efflux, and excessive secretion of pro-inflammatory cytokines.
Bailey A. Loving, Mikaela C. Neal, Sachi Gorkhali, Maoping Tang, Robert Murphy, Robert H. Eckel, Kimberley D. Bruce, Gorkhali, Sachi, Tang, Maoping, Eckel, Robert H, Murphy, Robert, Loving, Bailey A, Neal, Mikaela C, Bruce, Kimberley D   +13 more
core   +1 more source