Results 91 to 100 of about 557,479 (308)

Lipid accumulation mediated by adiponectin in C2C12 myogenesis

BMB Reports, 2009
Plasma concentrations of adiponectin have been shown to be decreased in patients with obesity, cardiovascular diseases, hypertension and metabolic syndrome. Recent studies have found that adiponectin reduces lipid accumulation in macrophage foam cells which may impact the development of atherosclerosis.
Changjun, Yin, Qinqiang, Long, Ting, Lei, Xiaodong, Chen, Huan, Long, Bin, Feng, Yin, Peng, Yanling, Wu, Zaiqing, Yang   +8 more
openaire   +3 more sources

Manipulation of lipid rafts in neuronal cells

, 2010
Lipid rafts are specialized plasma membrane micro-domains highly enriched in cholesterol, sphingolipids and glycosylphosphatidylinositol (GPI) anchored proteins.
Eckert, Gunter P.
core  

Rapid neutral lipid accumulation of the alkali-resistant oleaginous Monoraphidium dybowskii LB50 by NaCl induction

, 2014
NaCl is an effective inducer of lipid accumulation in freshwater microalgae, but little is known on whether the enhanced lipid components are desired. To address this issue, Monoraphidium dybowskii LB50 from a freshwater habitat was selected, cultivated,
Yang, Haijian, Xia, Ling, He, Qiaoning, Rong, Junfeng, Hu, Chunxiang   +4 more
core   +1 more source

Association between lipid accumulation products and stress urinary incontinence: a cross-sectional study from NHANES 2005 to 2018

Lipids in Health and Disease
Background Stress urinary incontinence (SUI), a common disorder of the pelvic floor, often results in anxiety, poor quality of life, and psychological issues among its sufferers.
JiHang Li, Dong Wang, Hu Tian, JianKun Yang, Hui Xia, WenBin Guo   +5 more
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Myocardial lipid accumulation and lipotoxicity in heart failure [PDF]

Journal of Lipid Research, 2009
The syndrome of chronic heart failure is a systemic disease state with primary cardiac dysfunction that subsequently affects multiple organ systems. After the primary cardiac insult, the clinical course of the patient is affected by comorbidities and the underlying type of cardiomyopathy.
openaire   +2 more sources

Elevated levels of erythrocyte-conjugated dienes indicate increased lipid peroxidation in schistosomiasis mansoni patients

, 2004
Schistosoma mansoni causes liver disease by inducing granulomatous inflammation. This favors formation of reactive oxygen species, including superoxide ions, hydrogen peroxide and hydroxyl radicals all of which may induce lipid peroxidation.
Owen, JS, Brandt, CT, Facundo, HT, Facundo, H.T.F., V.L.M. Lima, Lima, V.L.M., Lima, VL, J.S. Owen, Brandt, C.T., C.T. Brandt, H.T.F. Facundo, Owen, J.S.   +11 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

The Catalytic Domain of Neuropathy Target Esterase Influences Lipid Droplet Biogenesis and Lipid Metabolism in Human Neuroblastoma Cells

, 2022
As an endoplasmic reticulum (ER)-anchored phospholipase, neuropathy target esterase (NTE) catalyzes the deacylation of lysophosphatidylcholine (LPC) and phosphatidylcholine (PC).
Yijun Wu, Wu, Yijun, Xu, Li, Feifei Huang, Wang, Yu, He, Lin, Chang, Pingan, Lin He, Pingan Chang, Huang, Feifei, Yu Wang, Li Xu   +11 more
core   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source