Results 41 to 50 of about 858,616 (357)

Antioxidant activities of plant extracts and essential oil-cyclodextrin complexes and their effect on lipid accumulation in porcine adipocytes in vitro

Veterinary Integrative Sciences, 2021
Fat deposition is important for pig production because excessive fat decreases the economic value of meat production. Plant extracts have been used as feed additive in pig diets to improve oxidative stability of meat. However, only a few studies
Rakkiat Norkeaw, Chaiwat Arjin, Apinya Sartsook, Niraporn Chaiwang, Supamit Mekchay, Sarana Rose Sommano, Warintorn Ruksiriwanich, Korawan Sringarm   +7 more
doaj   +1 more source

Synthesis and accumulation of a receptor regulatory protein associated with lipid droplet accumulation in 3T3-L1 cells

Journal of Lipid Research, 1998
Synthesis and accumulation of the recently identified prostaglandin F2α receptor regulatory protein (FPRP) was found to correlate closely with lipid droplet accumulation by 3T3-L1 preadipose cells.
D.J. Orlicky, J.G. Lieber, C.L. Morin, R.M. Evans   +3 more
doaj   +1 more source

Development of a novel tocopheryl ester for suppression of lipid accumulation without cytotoxicity by optimization of dicarboxylic ester moiety

Biochemistry and Biophysics Reports, 2022
Tocopheryl succinate (Tsuc) is a succinic acid ester of the well-known antioxidant α-tocopherol (T). Tsuc exhibits various biological activities, including tumor growth suppression via activation of cell signaling and prevention of lipid accumulation in ...
Misaki Yamasaki, Yuika Seto, Mizune Ozono, Michiyasu Nakao, Akira Shigenaga, Akira Otaka, Shigeki Sano, Kentaro Kogure   +7 more
doaj   +1 more source

Lipid metabolism and storage in neuroglia: role in brain development and neurodegenerative diseases

Cell & Bioscience, 2022
The importance of neuroglia in maintaining normal brain function under physiological and pathological conditions has been supported by growing evidence in recent years.
Danying Yang, Xifeng Wang, Lieliang Zhang, Yang Fang, Qingcui Zheng, Xing Liu, Wen Yu, Shoulin Chen, Jun Ying, Fuzhou Hua   +9 more
doaj   +1 more source

Lipid accumulation product is a better predictor of metabolic syndrome in Chinese adolescents: a cross-sectional study

Frontiers in Endocrinology, 2023
AimConfirm and compare the degree of associations of non-traditional lipid profiles and metabolic syndrome (MetS) in Chinese adolescents, determine the lipid parameter with better predictive potential, and investigate their discriminatory power on MetS ...
Zi-yi Chen, Lei Liu, Xu-xiu Zhuang, Yi-cong Zhang, Ya-nan Ma, Yang Liu, De-liang Wen   +6 more
doaj   +1 more source

Nonalcoholic Lipid Accumulation and Hepatocyte Malignant Transformation [PDF]

Journal of Clinical and Translational Hepatology, 2016
Worldwide incidence of hepatocellular carcinoma (HCC) is steadily increasing, highlighting its status as a public health concern, particularly due to its significant association with other comorbidities, such as diabetes. However, nonalcoholic fatty liver disease (NAFLD) has emerged as a primary risk factor, with its own prevalence increasing in recent
Gu, Juanjuan, Yao, Min, Yao, Dengbing, Wang, Li, Yang, Xuli, Yao, Dengfu   +5 more
openaire   +2 more sources

Exploiting Bioprocessing Fluctuations to Elicit the Mechanistics of De Novo Lipogenesis in Yarrowia lipolytica. [PDF]

PLoS ONE, 2017
Despite substantial achievements in elucidating the metabolic pathways of lipogenesis, a mechanistic representation of lipid accumulation and degradation has not been fully attained to-date.
Andreas E Vasdekis, Andrew M Silverman, Gregory Stephanopoulos   +2 more
doaj   +1 more source

Transcriptome analyses reveal reduced hepatic lipid synthesis and accumulation in more feed efficient beef cattle [PDF]

, 2018
peer-reviewedThe genetic mechanisms controlling residual feed intake (RFI) in beef cattle are still largely unknown. Here we performed whole transcriptome analyses to identify differentially expressed (DE) genes and their functional roles in liver ...
Fitzsimmons, Carolyn, Keogh, Kate, Li, Changxi, Mukiibi, Robert, Stothard, Paul, Vinsky, Michael, Waters, Sinead M.   +6 more
core   +3 more sources

Chemical chaperone 4-phenyl butyric acid (4-PBA) reduces hepatocellular lipid accumulation and lipotoxicity through induction of autophagy[S]

Journal of Lipid Research, 2017
Defective autophagy has been linked to lipotoxicity in several cellular models. We aimed to investigate autophagy in lipid-stimulated hepatoma (Huh7) cells and tested whether 4-phenyl butyric acid (4-PBA), a chemical chaperone, has a beneficial role in ...
Ashraf U. Nissar, Love Sharma, Malik A. Mudasir, Lone A. Nazir, Sheikh A. Umar, Parduman R. Sharma, Ram A. Vishwakarma, Sheikh A. Tasduq   +7 more
doaj   +1 more source

TAK1-dependent autophagy: A suppressor of fatty liver disease and hepatic oncogenesis. [PDF]

, 2014
In addition to regulating the activation of nuclear factor (NF)-κB and c-Jun N-terminal kinase (JNK), TGF-β activated kinase 1 (TAK1) also upregulates the activation of AMP-activated protein kinase (AMPK) and autophagy.
Seki, Ekihiro
core   +2 more sources