Results 1 to 10 of about 1,320,816 (375)
Frontiers in Molecular Neuroscience, 2021 Once membrane potential changes or ligand binding activates the ion channel, the activity of the channel is finely modulated by the fluctuating membrane environment, involving local lipid composition and membrane tension.
Masayuki Iwamoto, Shigetoshi Oiki
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Antidepressants are modifiers of lipid bilayer properties
The Journal of General Physiology, 2019 The two major classes of antidepressants, tricyclic antidepressants (TCAs) and selective serotonin reuptake inhibitors (SSRIs), inhibit neurotransmitter reuptake at synapses.
Ruchi Kapoor +3 more
semanticscholar +1 more source
PLoS ONE, 2022 Lipid membranes in nature adapt and reconfigure to changes in composition, temperature, humidity, and mechanics. For instance, the oscillating mechanical forces on lung cells and alveoli influence membrane synthesis and structure during breathing ...
Marilyn Porras-Gómez +7 more
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Interactions of Novel Phosphonium Dye with Lipid Bilayers: A Molecular Dynamics Study
East European Journal of Physics, 2022 In the present work the 100-ns molecular dynamics simulations (MD) were performed in the CHARMM36m force field using the GROMACS package to estimate the bilayer location and mechanisms of the interaction between the novel phosphonium dye TDV and the ...
Olga Zhytniakivska
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Cholesterol's location in lipid bilayers [PDF]
Chemistry and Physics of Lipids, 2016 It is well known that cholesterol modifies the physical properties of lipid bilayers. For example, the much studied liquid-ordered Lo phase contains rapidly diffusing lipids with their acyl chains in the all trans configuration, similar to gel phase bilayers. Moreover, the Lo phase is commonly associated with cholesterol-enriched lipid rafts, which are
Marquardt, Drew +4 more
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Angewandte Chemie, 2017 Once removed from their natural environment, membrane proteins depend on membrane‐mimetic systems to retain their native structures and functions. To this end, lipid‐bilayer nanodiscs that are bounded by scaffold proteins or amphiphilic polymers such as ...
A. Oluwole +5 more
semanticscholar +1 more source
Swelling of phospholipid floating bilayers: the effect of chain length [PDF]
, 2003 The equilibrium distance between two lipid bilayers stable in bulk water and in proximity of a substrate was investigated. Samples consisted of a homogeneous lipid bilayer, floating near an identical bilayer deposited on the hydrophilic surface of a ...
Bellet-Amalric, Edith +4 more
core +5 more sources
Bioinspired, Size-Tunable Self-Assembly of Polymer-Lipid Bilayer Nanodiscs.
Angewandte Chemie, 2017 Polymer-based nanodiscs are valuable tools in biomedical research that can offer a detergent-free solubilization of membrane proteins maintaining their native lipid environment. Herein, we introduce a novel ca.
Thirupathi Ravula +3 more
semanticscholar +1 more source
Membranes, 2021 We characterized the size, distribution, and fluidity of microdomains in a lipid bilayer containing phosphatidylinositol (PI) and revealed their roles during the two-dimensional assembly of a membrane deformation protein (FBP17).
Toshinori Motegi +4 more
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Structure and hydration of membranes embedded with voltage-sensing domains. [PDF]
, 2009 Despite the growing number of atomic-resolution membrane protein structures, direct structural information about proteins in their native membrane environment is scarce.
Freites, J Alfredo +8 more
core +2 more sources