Results 91 to 100 of about 1,227,492 (388)
Membranes, 2022 Increasing antibiotic resistance has provoked the urgent need to investigate the interactions of antimicrobials with bacterial membranes. The reasons for emerging antibiotic resistance and innovations in novel therapeutic approaches are highly relevant ...
Shiqi Li +8 more
doaj +1 more source
The molecular structure of the liquid-ordered phase of lipid bilayers.
Journal of the American Chemical Society, 2014 Molecular dynamics simulations reveal substructures within the liquid-ordered phase of lipid bilayers. These substructures, identified in a 10 μs all-atom trajectory of liquid-ordered/liquid-disordered coexistence (L(o)/L(d)) are composed of saturated ...
A. Sodt +4 more
semanticscholar +1 more source
Protein induced lipid demixing in homogeneous membranes [PDF]
arXiv, 2021 Specific lipid environments are necessary for the establishment of protein signalling platforms in membranes, yet their origin has been highly debated. We present a continuum, exactly solvable model of protein induced local demixing of lipid membranes. The coupling between a local composition and a local thickness of the membrane induces lipid domains ...
arxiv
Molecular Oncology, EarlyView.Urine is a rich source of biomarkers for cancer detection. Tumor‐derived material is released into the bloodstream and transported to the urine. Urine can easily be collected from individuals, allowing non‐invasive cancer detection. This review discusses the rationale behind urine‐based cancer detection and its potential for cancer diagnostics ...
Birgit M. M. Wever +1 more
wiley +1 more source
Determination of biomembrane bending moduli in fully atomistic simulations. [PDF]
, 2014 The bilayer bending modulus (Kc) is one of the most important physical constants characterizing lipid membranes, but precisely measuring it is a challenge, both experimentally and computationally.
Brown, Frank LH +6 more
core
Sterols sense swelling in lipid bilayers [PDF]
, 1998 In the mimetic membrane system of phosphatidylcholine bilayers, thickening (pre-critical behavior, anomalous swelling) of the bilayers is observed, in the vicinity of the main transition, which is non-linear with temperature.
A. Blume +41 more
core +1 more source
Computational Investigation of the Effect of Lipid Membranes on Ion Permeation in Gramicidin A
Membranes, 2016 Membrane proteins are embedded in a lipid bilayer and interact with the lipid molecules in subtle ways. This can be studied experimentally by examining the effect of different lipid bilayers on the function of membrane proteins.
Jeffry Setiadi, Serdar Kuyucak
doaj +1 more source
A Simulation Study on Multicomponent Lipid Bilayer [PDF]
, 2005 Simulation of a multicomponent lipid bilayer having a fixed percentage of cholesterol is done to study phase transition leading to domain formation. The concept of random lattice has been used in simulation to account for the coupling between the internal and translational degrees of freedom of lipid molecules.
arxiv +1 more source
Critical adsorption controls translocation of polymer chains through lipid bilayers and permeation of solvent [PDF]
Europhys. Lett., 98, 1800 (2012), 2012 Monte Carlo simulations using an explicit solvent model indicate a new pathway for translocation of a polymer chain through a lipid bilayer. We consider a polymer chain composed of repeat units with a given hydrophobicity and a coarse-grained model of a lipid bilayer in the self-organized liquid state.
arxiv +1 more source
FEBS Open Bio, EarlyView.Ca2+‐mediated response to DMSO was investigated in Saccharomyces cerevisiae cells expressing Ca2+‐dependent aequorin. Cell exposure to DMSO induced a cytosolic Ca2+ wave dependent on the integrity of the Cch1/Mid1 channel. Deletion of KCS1 or VIP1 genes encoding the phosphoinositol pyrophosphate (PP‐IP) synthases suppressed the DMSO‐induced Ca2 ...
Larisa Ioana Gogianu +4 more
wiley +1 more source