Results 131 to 140 of about 1,228,036 (371)
The impact of nanomaterials on lung fluids, or on the plasma membrane of living cells, has prompted researchers to examine the interactions between nanoparticles and lipid vesicles. Recent studies have shown that nanoparticle-lipid interaction leads to a
Fanny Mousseau+4 more
doaj +1 more source
Exploring the Free Energy Landscape of Solutes Embedded in Lipid Bilayers.
Free energy calculations are vital for our understanding of biological processes on an atomistic scale and can offer insight to various mechanisms. However, in some cases, degrees of freedom (DOFs) orthogonal to the reaction coordinate have high energy ...
Joakim P. M. Jämbeck, A. Lyubartsev
semanticscholar +1 more source
Coherent collective dynamics in phospholipid membranes: where are we now?
We review the main achievements accomplished in the study of the coherent collective dynamics of phospholipid membranes, i.e., the collective vibrational excitations active on the sub-picoseconds to picoseconds time scale and terahertz frequencies, over ...
Valeria Conti Nibali+4 more
doaj +1 more source
Bright ion channels and lipid bilayers.
If we look at a simple organism such as a zebrafish under a microscope, we would see many cells working in harmony. If we zoomed in, we would observe each unit performing its own tasks in a special aqueous environment isolated from the other units by a ...
W. Szymański+3 more
semanticscholar +1 more source
Lipid Nanoparticle‐Mediated CRISPR‐Cas13a Delivery for the Control of Bacterial Infection
New formulations of lipid nanoparticles (LNPs) that can deliver nucleic acids to Gram‐negative bacteria are proposed to combat bacterial infection. The delivery of nucleic acids by LNPs is aided by LNP‐helpers which weaken the bacterial outer membrane. LNPs encapsulating the Cas13a/gRNA expression vector achieve an antibacterial effect in both in vivo ...
Bookun Kim+9 more
wiley +1 more source
An engineered dimeric protein pore that spans adjacent lipid bilayers
The bottom-up construction of artificial tissues is an underexplored area of synthetic biology. An important challenge is communication between constituent compartments of the engineered tissue, and between the engineered tissue and additional ...
Shiksha Mantri+5 more
semanticscholar +1 more source
Recent Applications of Mesoporous Silica Nanoparticles in Gene Therapy
The review summarizes the synthesis of mesoporous silica nanoparticles (MSNs) with modifiable surface properties, functionalization strategies, mechanism of therapeutic payload release, and current applications in gene therapy, focusing on their capabilities in the targeted delivery of therapeutic nucleic acids, CRISPR‐Cas systems, and other genetic ...
Tamanna Binte Huq+4 more
wiley +1 more source
A criterion to identify the equilibration time in lipid bilayer simulations [PDF]
With the aim of establishing a criterion for identifying when a lipid bilayer has reached steady state using the molecular dynamics simulation technique, lipid bilayers of different composition in their liquid crystalline phase were simulated in aqueous ...
Rodolfo D. Porasso+1 more
doaj
Concentration fluctuations and phase transitions in coupled modulated bilayers
We consider the formation of finite-size domains in lipid bilayers consisting of saturated and hybrid lipids. First, we describe a monolayer model that includes a coupling between a compositional scalar field and a two-dimensional vectorial order ...
A. Zachowski+4 more
core +1 more source
Fluorescence modulation sensing of positively and negatively charged proteins on lipid bilayers
BackgroundDetecting ligand-receptor binding on cell membrane surfaces is required to understand their function and behavior. Detection platforms can also provide an avenue for the development of medical devices and sensor biotechnology.
A. D. Robison+3 more
semanticscholar +1 more source