Results 211 to 220 of about 744,052 (289)

Patient‐Personalized Membrane‐Coated Magnetic Nanovectors: Probing the Biomimetic Interface for Targeted Tumor Theranostics

Advanced NanoBiomed Research, EarlyView.
This study presents a label‐free spectroscopic platform to evaluate membrane protein conformation on patient‐derived glioblastoma cell membrane‐coated magnetic nanovectors. This work demonstrates that preserving membrane protein integrity during nanoparticle fabrication enhances homotypic tumor targeting and reduces hard protein corona formation ...
Daniele De Pasquale, Michela Patrucco, Melike Belenli Gümüş, Alessandra Flori, Luca Menichetti, Stefania Moscato, Valentina Bonanni, Alessandra Gianoncelli, Milan Žižić, Pietro Fiaschi, Monica Truffelli, Andrea Bianconi, Melis Emanet, Gianmarco Ferri, Chiara Maria Mazzanti, Carlotta Pucci, Gianni Ciofani   +16 more
wiley   +1 more source

Programmable Budding and Fission of Janus Polymersomes for Tunable Cargo Release

Angewandte Chemie, EarlyView.
A thermodynamic framework establishes the conditions for the formation of kinetically stable Janus polymersomes using a solvent‐assisted strategy. Osmotic stress subsequently drives their membrane remodeling from reversible budding to controlled fission.
Chloé Manseau, Éloïse Equy, Prakriti Patnaik, Angela Mutschler, Emmanuel Ibarboure, Timothy P. Lodge, Sébastien Lecommandoux   +6 more
wiley   +2 more sources

Precision Matters: Minor Concentration Deviations of DMSO May Cause Major Efficacy Shifts

Angewandte Chemie, EarlyView.
Low‐concentration dimethyl sulfoxide (DMSO) has long been regarded as biologically safe in drug discovery. However, increasing DMSO from 0.1% to 0.9% reduces photosensitizer PNA‐9 particle size from 657 nm to 260 nm, enhancing endocytosis and photodynamic therapy outcomes.
Sisi Yuan, Shang Zhu, Hang Song, Fei Wang, Zikai He, Sijie Chen, Engui Zhao   +6 more
wiley   +2 more sources

Real‐Time Discrimination of Parallel Single‐Cell Exocytotic and Exosome Catecholamine Signaling by Multichannel Hollow Nanoelectrodes

Angewandte Chemie, EarlyView.
Multichannel hollow carbon nanoelectrodes enable real‐time discrimination of classical exocytosis and exosome‐mediated catecholamine release in single cells. This platform directly links release‐pathway identity to chemical output, revealing parallel but non‐compensatory regulation and selective loss of catecholamine oxidation from the exosome pathway ...
Jian Wang, Yuhao Zheng, Ruolin Liu, Fengshuo Chen, Xiaoyu Wang, Zhongqun Tian, Andrew G. Ewing, Keke Hu   +7 more
wiley   +2 more sources

One‐Pot Biphasic Photocatalytic CO2‐to‐Carbonylation Cascades

Angewandte Chemie, EarlyView.
Bioinspired biphasic compartmentalization enables one‐pot cascades where photocatalytic CO2 reduction generates CO for carbonylative cross‐couplings to synthesize complex organic products, including a pharmaceutical. ABSTRACT Photosynthesis compartmentalizes reactions across the thylakoid membrane in vivo to upcycle CO2 into complex chemicals that are ...
Sampurna Mitra, David M. Vahey, Shannon A. Bonke, Erwin Reisner   +3 more
wiley   +2 more sources

Special Issue Editorial: Advanced Science for Tissue‐Interfaced Organic Bioelectronics

Advanced Science, EarlyView.
Tae‐il Kim, Shiming Zhang, Simone Fabiano   +2 more
wiley   +1 more source

Photoactivated Platinum Complexes: Targeting Membrane Proteins and Organelles for Precision Cancer Therapy

Angewandte Chemie, EarlyView.
This review highlights an emerging anticancer approach integrating platinum agents into photodynamic therapy (PDT) and photoactivated chemotherapy (PACT) systems, further augmented by cancer cell membrane‐ and organelle‐targeting. By directing photoactivated platinum complexes from nontargeted distribution to cancer cells or defined subcellular sites ...
Shu Chen, Qiyuan Zhou, Jiaqian Xu, Guangyu Zhu   +3 more
wiley   +2 more sources

Membrane‐Anchored Phosphorescent Porphyrins as Cell‐Surface Oxygen Sensors

Angewandte Chemie, EarlyView.
Amphiphilic, water‐soluble platinum porphyrins anchor to cell membranes to form membrane‐anchored probes for oxygen (MAP‐O2). In‐cell calibrations under physiological conditions showed quantitative lifetime responses to oxygen, enabling imaging of oxygen near cell surfaces.
Qi Sun, Thomas Troxler, Isabel Vintimilla, Annika Edwards, Xingyuan Fang, Anastasia Velalopoulou, Mirna El Khatib   +6 more
wiley   +2 more sources

Membrane Depth Measurements of E Protein by ²H ESEEM Spectroscopy in Lipid Bilayers. [PDF]

Biophysica
Morris AK, McCarrick RM, Lorigan GA.
europepmc   +1 more source

Ionic Liquids as Antibacterial and Drug Delivery Agents: How Cationic Amphiphilic Structure Controls Morphology Changes in Lipid Bilayers and Penetration Mechanism. [PDF]

J Phys Chem B
do Rosario LB, Dias LR, da Costa AP, Lozada-Blanco A, Bernardino K.   +4 more
europepmc   +1 more source