Results 91 to 100 of about 142,764 (304)

Expanding roles for lipid droplets [PDF]

Trends in Endocrinology & Metabolism, 2011
This work was supported by grants from the American Diabetes Association, NIH RO1-DK-082574, and the U.S. Department of Agriculture, Agricultural Research Service, under agreement No. 58-1950-7-70 to ASG. This work was also supported by grants from the NIH RO1-DK59935 and RO1 DK56598 to RAC.
Andrew S, Greenberg, Rosalind A, Coleman
openaire   +2 more sources

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

FEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman, Katarzyna Stapor, Leszek Konieczny, Krzysztof Gądek, Piotr Nowakowski   +4 more
wiley   +1 more source

Making Droplet-Embedded Vesicles to Model Cellular Lipid Droplets

STAR Protocols, 2020
Summary: We present a reproducible protocol to prepare droplet-embedded vesicles (DEVs) consisting of an oil droplet embedded within a phospholipid bilayer.
Aymeric Chorlay, Alexandre Santinho, Abdou Rachid Thiam   +2 more
doaj   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

FEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata, Yoichi Sakai, Keisuke Tanaka, Etsuro Yoshimura, Ken Kitano, Morio Ishikawa, Tadahiro Nakamoto, Tsutomu Takayama, Hirofumi Inoue, Kaho Nomura, Tomonori Suzuki, Masataka Uchino, Akira Abe, Youichi Niimura   +13 more
wiley   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

Lactate alleviates early brain damage after subarachnoid hemorrhage: Regulation of lipid metabolism

Neural Regeneration Research
This study investigated the neuroprotective effects of lactate in subarachnoid hemorrhage, a severe cerebrovascular disease that is commonly caused by arterial aneurysm rupture and has limited early treatment options.
Zichen Zhang, Xinan Li, Xiaoli Liu, Lei Chen, Yunzhi Wang, Enyan Jiang, Jia Zeng, Xiaojian Zhang, Zhen Fang, Zibin Liang, Jikai Wang, Fei Liu   +11 more
doaj   +1 more source

Preparation, characterisation and application of naturally derived polar lipids through lipolysis : a thesis presented in partial fulfilment of the requirements for the degree of Doctor of Philosophy in Food Technology at Massey University, Palmerston North, New Zealand [PDF]

, 2016
Monoglycerides are lipid based emulsifiers extensively used for their broad technical function in the food industry. Commercial monoglycerides are generally manufactured through chemical synthesis; however, lipolysis of triglycerides by lipase enzyme ...
Sofian-Seng, Noor-Soffalina
core  

Influence of process variables on the properties of simvastatin self-emulsifying granules obtained through high shear wet granulation [PDF]

, 2015
Improvements of the oral bioavailability of lipophilic drugs can be obtained using lipidic formulations such as the self-emulsifying drug delivery systems.
Benda L., FRANCESCHINIS, ERICA, Perssutti B., REALDON, NICOLA, SANTOMASO, ANDREA CLAUDIO, Voinovich D.   +5 more
core   +1 more source

Analysis of Lipid Droplets in Hepatocytes

, 2013
The liver plays an important role in triacylglycerol (TG) metabolism. It can store large amounts of TG in cytosolic lipid droplets (CLDs), or it can package TG into very-low density lipoproteins (VLDL) that are secreted from the cell. TG packaged into VLDL is derived from TG stored within the endoplasmic reticulum in lumenal lipid droplets (LLDs ...
Wang, Huajin, Quiroga, Ariel Dario, Lehner, Richard   +2 more
openaire   +4 more sources

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source