Results 111 to 120 of about 870,619 (302)
Lipid droplet staining of LX-2 cells.
, 2013 LX-2 cells grown for 72h were stained for lipid droplets by Oil Red O staining. A (A) positive control of LX-2 cells treated with MDI to induce lipid droplet storage, as described in previous experiments [13,15], was stained and observed to stain for ...
Kylie R. James (423666) +4 more
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Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To evaluate the expression of nine blood RNA biomarkers in a clinical trial based on genes previously identified in an experimental monkey model of stroke for diagnosis feasibility and prognostication. Methods IBIS‐CT1 was a prospective longitudinal study enrolling patients with ischemic stroke (IS) or intracerebral hemorrhage (ICH ...
Salomé Retailleau +11 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Hereditary Spastic Paraplegia (HSP) comprises a group of rare genetic diseases characterized by length‐dependent axonal degeneration of the corticospinal tracts and dorsal columns, whose main clinical feature is spastic gait. Pathogenic variants in the SPG4 gene cause Spastic Paraplegia Type 4 (SPG4‐HSP), the most common form of HSP.
Gaia Fattorini +12 more
wiley +1 more source
Identification of the lipid droplet targeting domain of the Cidea protein[S]
Journal of Lipid Research, 2010 Cidea, the cell death-inducing DNA fragmentation factor-α-like effector (CIDE) domain-containing protein, is targeted to lipid droplets in mouse adipocytes, where it inhibits triglyceride hydrolysis and promotes lipid storage.
Jennifer L. Christianson +4 more
doaj +1 more source
Arthritis Care &Research, EarlyView.Objective Routine liver enzyme monitoring is advocated for while on allopurinol, but supporting guidance is lacking. We assessed the incidence and factors associated with elevated liver enzyme levels in patients with gout commenced on allopurinol. Methods One hundred and fifty patients with gout and normal baseline serum aminotransferases initiated on ...
May Shuen Tang +4 more
wiley +1 more source
Autophagy and Lipid Droplets in the Liver
Annual Review of Nutrition, 2015 Autophagy is a conserved quality-control pathway that degrades cytoplasmic contents in lysosomes. Autophagy degrades lipid droplets through a process termed lipophagy. Starvation and an acute lipid stimulus increase autophagic sequestration of lipid droplets and their degradation in lysosomes.
Nuria, Martinez-Lopez, Rajat, Singh
openaire +3 more sources
A 3,4-dimethoxy-1,8-naphthalimide for lipid droplet imaging in live and fixed cells
, 2022 A 3,4-dimethoxy-1,8-naphthalimide for lipid droplet imaging in live and fixed ...
MJ Sweetman (18722656) +7 more
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Laser‐Induced Graphene from Waste Almond Shells
Advanced Functional Materials, EarlyView.Almond shells, an abundant agricultural by‐product, are repurposed to create a fully bioderived almond shell/chitosan composite (ASC) degradable in soil. ASC is converted into laser‐induced graphene (LIG) by laser scribing and proposed as a substrate for transient electronics.
Yulia Steksova +9 more
wiley +1 more source
An inside job:New roles for ApoE at the lipid droplet
The secreted ApoE protein is a major regulator of lipid transport between brain cells. In this issue, Windham et al. (https://doi.org/10.1083/jcb.202305003) uncover a novel intracellular role for ApoE at the lipid droplet surface, where it regulates ...
Feringa, Femke M.; id_orcid +1 more
core +1 more source
The Science and Technology of Automatable Droplet Lipid Bilayer Platforms [PDF]
, 2012 Droplet lipid bilayers have been shown to be robust platforms for studying membrane proteins in a highly controlled environment. They are stable and can be formed using automated fluid handling techniques. Measuring membrane protein activity and compound
Portonovo, Shiva A.
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