Results 131 to 140 of about 870,619 (302)

Beyond Primary Nucleation: Molecular Basis of Peptide Crystal Secondary Nucleation at Soft Interface

Advanced Functional Materials, EarlyView.
High spatiotemporal‐resolution atomic force microscopy directly resolved peptide secondary nucleation (SN) and growth characteristics and mechanisms on HOPG. The landscape of peptide nucleation sites, growth dynamics, molecular‐scale structures, phase transitions, and cross‐seeding processes were realized.
Linhao Sun, Abilesh Kumar, Ayhan Yurtsever   +2 more
wiley   +1 more source

Droplet Shape Analysis and Permeability Studies in Droplet Lipid Bilayers

, 2016
We apply optical manipulation to prepare lipid bilayers between pairs of water droplets immersed in an oil matrix. These droplet pairs have a well-defined geometry allowing the use of droplet shape analysis to perform quantitative studies of the dynamics
Sanhita S. Dixit (2083894), Gregory W. Faris (2083897), Alexandra Pincus (2083891), Bin Guo (142004)   +3 more
core   +2 more sources

Lipid droplet movies in polarized WIF-B cells

, 2019
Video files (8) of lipid droplet dynamics in hepatic cells treated with oleic acid in the absence or presence of ethanol or alphaTAT1 expression.
Pamela Tuma (6285212)
core   +1 more source

Biodegradable Conductors for Implantable and Wearable Transient Bioelectronics

Advanced Functional Materials, EarlyView.
Biodegradable conductors are essential building blocks for transient bioelectronics, enabling temporary sensing, stimulation, and energy transfer while eliminating the need for device retrieval. This review summarizes biodegradable metals, conducting polymers, ionic conductors, and conductive composites, highlighting degradation mechanisms, material ...
Yicheng Zhu, Yijun Liu, Naoji Matsuhisa
wiley   +1 more source

Engineering Antigen Density on M13 Bacteriophage for Personalized Nanovaccine

Advanced Healthcare Materials, EarlyView.
Increasing antigen density on the phage capsid impacts phage uptake and antigen cross‐presentation by antigen‐presenting cells, leading to enhanced activation of antitumor CD8+ T cells in the draining lymph nodes. These activated CD8+ T cells subsequently recognize the antigen‐expressing tumors and mediate their specific cytotoxic killing, thereby ...
Shengnan Huang, Allison Madow, Jack Rudrum, Huaiyao Peng, Hao Nghi Luu, Peiyan Dong, Jifa Qi, Angela M. Belcher   +7 more
wiley   +1 more source

Unravelling the effect of droplet size on lipid oxidation in O/W emulsions by using microfluidics

Scientific Reports
Lipid oxidation in emulsions is hypothesised to increase with decreasing droplet size, as this increases the specific oil–water interfacial area, where lipid oxidation is expected to be initiated.
Sten ten Klooster, Vincent J. P. Boerkamp, Marie Hennebelle, John P. M. van Duynhoven, Karin Schroën, Claire C. Berton-Carabin   +5 more
doaj   +1 more source

Lipid droplet detection in histopathological images using reinforcement learning

Biotechnology & Biotechnological Equipment
The identification and analysis of lipid droplets in pathological images are pivotal owing to the variations in their size, shading and shape. The development of an artificial intelligence-based automatic detection method can facilitate the analysis of ...
Yoshitomi Harada, Haruto Nishida, Keiko Matsuura   +2 more
doaj   +1 more source

Atom‐Efficient Cerium‐Based Molecular Cages as Biocompatible Reactive Oxygen Scavengers

Advanced Healthcare Materials, EarlyView.
Discrete mixed‐valent cerium molecular cages organize accessible redox centers within confined coordination environments and scavenge superoxide, hydrogen peroxide, and hydroxyl radicals. Encapsulation of the lead cage in an ROS‐responsive DTP nanoplatform enables lesion‐associated delivery, attenuates macrophage oxidative stress and inflammation, and ...
Chao Li, Chunbai Xiang, Ye Xu, Yu Liu, Keze Hong, Fanchu Zeng, Gelin Xu, Zhao‐Xi Wang, Jonathan L. Sessler, Ping Gong   +9 more
wiley   +1 more source

Quantum Dot-Based Designed Nanoprobe for Imaging Lipid Droplet

, 2017
Lipid droplet is a dynamic subcellular organelle, and its imaging is important for understanding its functional role toward the cellular-scale origin of many diseases.
Suman Mandal (4518577), Suman Mandal, Nikhil R. Jana, Nikhil R. Jana (1268586)   +3 more
core   +1 more source

Increasing Lipid Nanoparticle mRNA Copy Number Improves Transfection Potency

Advanced Materials, EarlyView.
As lipid nanoparticle (LNP) systems are the leading platform for in vivo nucleic acid delivery, improving transfection potency of these systems is of considerable interest. In this work, we explored a post‐mixing formulation method involving a two‐step buffer exchange that increased the number of mRNA copies within each LNP while reducing the number of
Yao Zhang, Jerry Leung, Judy Cheng, Arash Momeni, Albert Kamanzi, Ariadne Tuckmantel Bido, Suiyang Liao, Emma Kang, Colton Strong, Christian J. Kastrup, Sabrina Leslie, Miffy Hok Yan Cheng, Pieter R. Cullis   +12 more
wiley   +1 more source