Results 101 to 110 of about 142,764 (304)

Alkyl gallates disrupt Trypanosoma brucei lipid droplets.

open access: yesPLoS ONE
African trypanosomiasis is a deadly disease that affects humans and animals, with treatment hindered by drug toxicity and resistance, highlighting the need for alternative therapies.
Cynthia Mmalebna Amisigo   +3 more
doaj   +1 more source

Identification of the lipid droplet targeting domain of the Cidea protein[S]

open access: yesJournal of Lipid Research, 2010
Cidea, the cell death-inducing DNA fragmentation factor-α-like effector (CIDE) domain-containing protein, is targeted to lipid droplets in mouse adipocytes, where it inhibits triglyceride hydrolysis and promotes lipid storage.
Jennifer L. Christianson   +4 more
doaj   +1 more source

Influence of Micro-mixing on the Size of Liposomes Self-Assembled from Miscible Liquid Phases

open access: yes, 2013
Ethanol injection and variations of it are a class of methods where two miscible phases---one of which contains dissolved lipids---are mixed together leading to the self-assembly of lipid molecules to form liposomes. This method has been suggested, among
Phapal, Sopan, Sunthar, P
core   +2 more sources

Chemical communication between synthetic and natural cells: a possible experimental design [PDF]

open access: yes, 2013
The bottom-up construction of synthetic cells is one of the most intriguing and interesting research arenas in synthetic biology. Synthetic cells are built by encapsulating biomolecules inside lipid vesicles (liposomes), allowing the synthesis of one or ...
D'Angelo, Francesca   +5 more
core   +3 more sources

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

open access: yesAging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey   +12 more
wiley   +1 more source

Plasma EV Proteomics Identifies ECM Remodeling and Inflammatory Proteins LUM and C7 as Candidate Biomarkers in FSHD

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit   +11 more
wiley   +1 more source

A transient solution for vesicle electrodeformation and relaxation

open access: yes, 2012
A transient analysis for vesicle deformation under DC electric fields is developed. The theory extends from a droplet model, with the additional consideration of a lipid membrane separating two fluids of arbitrary properties.
Lin, Hao   +3 more
core   +1 more source

Glucocorticoid Receptor and Adipocyte Biology. [PDF]

open access: yes, 2018
Glucocorticoids are steroid hormones that play a key role in metabolic adaptations during stress, such as fasting and starvation, in order to maintain plasma glucose levels.
Harris, Charles A   +2 more
core   +2 more sources

Perceived Impacts and Predictors of Cannabis Products Used by Patients with Rheumatologic Conditions in Alberta, Canada: A Multivariable Analysis of Cross‐Sectional Survey Data

open access: yesArthritis Care &Research, EarlyView.
Objective This study aimed to characterize cannabis product choices (cannabinoid content and formulation) among patients with rheumatologic conditions and their associations with patient factors, patient‐reported perceived side effects, and positive impacts.
Susan Zhang   +10 more
wiley   +1 more source

Solvent-free coarse-grained lipid model for large-scale simulations

open access: yes, 2010
A coarse-grained molecular model, which consists of a spherical particle and an orientation vector, is proposed to simulate lipid membrane on a large length scale.
Allen M. P.   +6 more
core   +1 more source

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