Results 51 to 60 of about 142,764 (304)
Cell-free protein expression systems in microdroplets: stabilization of interdroplet bilayers
, 2013 Cell-free protein expression with bacterial lysates has been demonstrated to produce soluble proteins in microdroplets. However, droplet assays with expressed membrane proteins require the presence of a lipid bilayer.
Hywel Morgan +3 more
core +1 more source
Current Opinion in Cell Biology, 2019 Lipid droplets (LDs) store neutral lipids in their core as an energy source when nutrients are scarce. The center of an LD is hydrophobic, and hence it is surrounded by a phospholipid monolayer, unlike other organelles that have an aqueous interior and are bounded by a phospholipid bilayer.
openaire +3 more sources
Lipid Droplets in Neurodegenerative Disorders [PDF]
Frontiers in Neuroscience, 2020 Knowledge of lipid droplets (LDs) has evolved from simple depots of lipid storage to dynamic and functionally active organelles involved in a variety of cellular functions. Studies have now informed significant roles for LDs in cellular signaling, metabolic disease, and inflammation.
Brandon C. Farmer +4 more
openaire +3 more sources
A new fluorescence-based method identifies protein phosphatases regulating lipid droplet metabolism.
PLoS ONE, 2010 In virtually every cell, neutral lipids are stored in cytoplasmic structures called lipid droplets (LDs) and also referred to as lipid bodies or lipid particles.
Bruno L Bozaquel-Morais +4 more
doaj +1 more source
Organellar Contacts of Milk Lipid Droplets
Contact, 2020 Milk-secreting epithelial cells of the mammary gland are functionally specialized for the synthesis and secretion of large quantities of neutral lipids, a major macronutrient in milk from most mammals.
Jenifer Monks +2 more
doaj +1 more source
Modulation of triglyceride and cholesterol ester synthesis impairs assembly of infectious hepatitis C virus [PDF]
, 2014 In hepatitis C virus infection, replication of the viral genome and virion assembly are linked to cellular metabolic processes. In particular, lipid droplets, which store principally triacylglycerides (TAGs) and cholesterol esters (CEs), have been ...
Hague, Charlotte V. +4 more
core +1 more source
Redox BiologyLipid droplet accumulation in microglia has been implicated in inflammatory functions associated with aging and demyelinating diseases. However, the molecular mechanisms driving lipid droplet formation under pathological conditions remain unrevealed.
Fengchen Zhang +9 more
doaj +1 more source
Microfluidics for Advanced Drug Delivery Systems. [PDF]
, 2015 Considerable efforts have been devoted towards developing effective drug delivery methods. Microfluidic systems, with their capability for precise handling and transport of small liquid quantities, have emerged as a promising platform for designing ...
Dokmeci, Mehmet R +5 more
core +1 more source
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Microfluidic generation of networked droplet collections and lipid membrane constructs [PDF]
, 2014 We report on microfluidic strategies to generate several multi-compartment membrane-based structures, including droplet interface bilayer networks and multi-compartment vesicles.
Ces, O, Elani, Y, Law, R
core