Results 131 to 140 of about 1,446,619 (399)

An optimized histochemical method to assess skeletal muscle glycogen and lipid stores reveals two metabolically distinct populations of type I muscle fibers. [PDF]

PLoS ONE, 2013
Skeletal muscle energy metabolism has been a research focus of physiologists for more than a century. Yet, how the use of intramuscular carbohydrate and lipid energy stores are coordinated during different types of exercise remains a subject of debate ...
Clara Prats, Alba Gomez-Cabello, Pernille Nordby, Jesper L Andersen, Jørn W Helge, Flemming Dela, Otto Baba, Thorkil Ploug   +7 more
doaj   +1 more source

Perturbed cholesterol and vesicular trafficking associated with dengue blocking in Wolbachia-infected Aedes aegypti cells [PDF]

, 2017
Wolbachia are intracellular maternally inherited bacteria that can spread through insect populations and block virus transmission by mosquitoes, providing an important approach to dengue control.
Ant, Thomas H., Charles, Philip D., Dowle, Adam A., Geoghegan, Vincent, Hester, Svenja, Larson, Tony, Rainey, Stephanie M., Sinkins, Steven P., Stainton, Kirsty, Thomas, Benjamin   +9 more
core   +3 more sources

Spastin tethers lipid droplets to peroxisomes and directs fatty acid trafficking through ESCRT-III

bioRxiv, 2019
Lipid droplets (LDs) are neutral lipid storage organelles that transfer lipids to various organelles including peroxisomes. Here, we show that the hereditary spastic paraplegia protein M1 Spastin, a membrane-bound AAA ATPase found on LDs, coordinates ...
Chi-Lun Chang, Aubrey V. Weigel, Maria S. Ioannou, H. Pasolli, C. Xu, D. Peale, G. Shtengel, Melanie Freeman, H. Hess, C. Blackstone, J. Lippincott-Schwartz   +10 more
semanticscholar   +1 more source

Lipid Droplets as Organelles [PDF]

, 2018
Long considered inert fat storage depots, it has become clear that lipid droplets (LDs) are bona fide organelles. Like other organelles, they have a characteristic complement of proteins and lipids, and undergo a life cycle that includes biogenesis, maturation, interactions with other organelles, and turnover.
openaire   +2 more sources

NR4A1 Exerts Pro‐Tumor Role in Glioblastoma via Inducing xCT/GPX4‐Regulated Ferroptosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Purpose This study investigates NR4A1's paradoxical roles in glioblastoma (GBM) progression, focusing on its mechanistic link to ferroptosis regulation. We aimed to resolve conflicting reports of NR4A1 as both an oncogene and a tumor suppressor by defining its transcriptional control over xCT/GPX4‐mediated iron homeostasis and its clinical ...
Peng Tao, Shikuan Din, Zhengkang Fu, Qian Sun, Xiwei Zhu, Yuxin Wei, Huan Qu, Xinyi Zhang, Jiaxuan Liu, Chuhua Fu, Qianxue Chen   +10 more
wiley   +1 more source

Belousov-Zhabotinsky droplet mixing on-chip for chemical computing applications

, 2013
Without an imposed physical structure, even the most complex chemistries are limited in their ability to process information. For example, the Belousov-Zhabotinsky (BZ) oscillating reaction has been shown to have information procession potential, but ...
de Planque, Maurits R.R., Jones, Gareth, King, Philip H., Morgan, Hywel, Zauner, Klaus-Peter   +4 more
core  

Changes in lipid droplet localization during embryogenesis of the silkworm, Bombyx mori. [PDF]

, 2008
Lipid droplets are considered one of the most important energy sources in lepidopteran eggs during late embryogenesis, but the process of their incorporation into the embryo is as yet unknown.
5350, 5351, 5352, Hariyama, Takahiko, Seno, Keiji, 山濱, 由美   +5 more
core   +2 more sources

SNUPN‐Related Muscular Dystrophy: Novel Phenotypic, Pathological and Functional Protein Insights

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective SNUPN‐related muscular dystrophy or LGMDR29 is a new entity that covers from a congenital or childhood onset pure muscular dystrophy to more complex phenotypes combining neurodevelopmental features, cataracts, or spinocerebellar ataxia. So far, 12 different variants have been described.
Nuria Muelas, Pablo Iruzubieta, Alberto Damborenea, Laura Pérez‐Fernández, Inmaculada Azorín, Juan Carlos Jiménez García, Ana Töpf, Pilar Martí, Lorena Fores‐Toribio, María Manterola, Rosana Blanco‐Mañez, Oihane Pikatza‐Menoio, Sonia Alonso‐Martín, Volker Straub, Aitziber L. Cortajarena, Adolfo López de Munain, David De Sancho, Lorea Blázquez, Juan J. Vilchez   +18 more
wiley   +1 more source

Foam cell formation containing lipid droplets enriched with free cholesterol by hyperlipidemic serum

Journal of Lipid Research, 2001
A monoclonal antibody, ASH1a/256C (256C), which binds to atherosclerotic lesions in Watanabe heritable hyperlipidemic rabbit (WHHL) aorta in vivo, recognizes complex structures of phosphatidylcholine mixed with neutral lipids.
Masahiro Mori, Hiroyuki Itabe, Yusuke Higashi, Yasuyuki Fujimoto, Masahiro Shiomi, Masao Yoshizumi, Yasuyoshi Ouchi, Tatsuya Takano   +7 more
doaj   +1 more source

Nectar and oleiferous trichomes as floral attractants in Bulbophyllum saltatorium Lindl. (Orchidaceae) [PDF]

, 2017
Although many Orchidaceae have deceit flowers that produce no reward, the most common reward, when present, is nectar. Bulbophyllum, however, is unusual in that the labellar secretions of most species investigated to date lack sugars, and, therefore ...
Davies, Kevin L., Płachno, Bartosz, Stpiczyńska, Małgorzata   +2 more
core   +1 more source