Results 71 to 80 of about 174,447 (304)

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Effects of dietary retinoid and triglyceride on the lipid composition of rat liver stellate cells and stellate cell lipid droplets

Journal of Lipid Research, 1988
Hepatic stellate cells store the majority of the liver's retinoid (vitamin A) reserves as retinyl esters in stellate cell lipid droplets. A study was conducted to explore the effects of differences in dietary retinoid and triglyceride intake on the ...
H Moriwaki, W S Blaner, R Piantedosi, D S Goodman   +3 more
doaj   +1 more source

Adipose triglyceride lipase protects renal cell endocytosis in a Drosophila dietary model of chronic kidney disease.

PLoS Biology, 2021
Obesity-related renal lipotoxicity and chronic kidney disease (CKD) are prevalent pathologies with complex aetiologies. One hallmark of renal lipotoxicity is the ectopic accumulation of lipid droplets in kidney podocytes and in proximal tubule cells ...
Aleksandra Lubojemska, M Irina Stefana, Sebastian Sorge, Andrew P Bailey, Lena Lampe, Azumi Yoshimura, Alana Burrell, Lucy Collinson, Alex P Gould   +8 more
doaj   +1 more source

Ultrastructural analysis of lipid incorporation in the embryonic silkworm, Bombyx mori. [PDF]

, 2009
Insect eggs store many lipid droplets as an energy source for embryonic development. We previously reported that lipid droplets are incorporated into embryos in three steps in the silkworm, Bombyx mori.
5345, 5346, 5347, 5348, 5349, Hariyama, Takahiko, Kumakiri, Yoko, Muranaka, Yoshinori, Tamotsu, Satoshi, 山濱, 由美   +9 more
core   +2 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Conditional targeting of phosphatidylserine decarboxylase to lipid droplets

Biology Open, 2021
Phosphatidylethanolamine is an abundant component of most cellular membranes whose physical and chemical properties modulate multiple aspects of organelle membrane dynamics. An evolutionarily ancient mechanism for producing phosphatidylethanolamine is to
Santosh Kumar, Chandramohan Chitraju, Robert V. Farese, Tobias C. Walther, Christopher G. Burd   +4 more
doaj   +1 more source

Direct extraction of oil from sunflower seeds by twin-screw extruder according to an aqueous extraction process: Feasibility study and influence of operating conditions [PDF]

, 2007
The objective of this study was to evaluate the feasibility of an aqueous process to extract sunflower seed oil using a co-rotating twin-screw extruder. Aqueous extraction was carried out using whole seeds and the influence of the operating conditions on
Amalia Kartika, Amalia Kartika, Bligh, Choudhury, Domínguez, Domínguez, Dziezak, Fullbrook, Galvin, Gautam, Gautam, Gogoi, Hagenmaier, Isobe, L. Rigal, Lacaze-Dufaure, Lacaze-Dufaure, Lanzani, P.Y. Pontalier, Ph. Evon, Rigal, Rosenthal, Sineiro, Southwell, V. Vandenbossche, Van Soest, Van Soest   +26 more
core   +4 more sources

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Ergosterol reduction impairs mitochondrial DNA maintenance in S. cerevisiae [PDF]

, 2019
Sterols are essential lipids, involved in many biological processes. In Saccharomyces cerevisiae, the enzymes of the ergosterol biosynthetic pathway (Erg proteins) are localized in different cellular compartments.
Balliano, Gianni, Bianchi, Michele Maria, Cirigliano, Angela, Macone, Alberto, Negri, Rodolfo, Oliaro-Bosso, Simonetta, Rinaldi, Teresa   +6 more
core   +2 more sources

The life of lipid droplets [PDF]

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 2009
Lipid droplets are the least characterized of cellular organelles. Long considered simple lipid storage depots, these dynamic and remarkable organelles have recently been implicated in many biological processes, and we are only now beginning to gain insights into their fascinating lives in cells.
Walther, T., Farese, R.
openaire   +3 more sources