Results 61 to 70 of about 863,741 (256)
Imaging of lipid biosynthesis: how a neutral lipid enters lipid droplets
, 2008 The biosynthesis and storage of triglyceride (TG) is an important cellular process conserved from yeast to man. Most mammalian cells accumulate TG in lipid droplets, most prominent in adipocytes, which are specialized to store large amounts of the TG ...
Christine Moessinger +5 more
core +2 more sources
Triglyceride containing lipid droplets and lipid droplet-associated proteins
, 2008 PURPOSE OF REVIEW: Cytosolic lipid droplets are now recognized as dynamic organelles. This review summarizes our current understanding of the mechanisms involved in the formation of lipid droplets, the importance of lipid droplet-associated proteins and ...
Borén, Jan, +6 more
core +1 more source
, 2020 Lipid droplets are organelles that store neutral lipids. Many metabolic disorders are associated with altered lipid droplet storage. Proteins of the Plin family regulate lipid droplet stability and are potential therapeutic targets of metabolic diseases.
Li, Yuchuan
core +1 more source
MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis
FEBS Open Bio, EarlyView.MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss +7 more
wiley +1 more source
Communications Biology, 2023 The small molecule SB2301 activates lipophagy and alters lipid droplet membrane composition, with the ethanolamine-phosphate cytidylyltransferase 2 (PCYT2) being a potential target of the compound.
Jinjoo Jung +5 more
doaj +1 more source
Quality control lipid droplets.
, 2013 Total protein extracts and purified lipid droplets from GFP, AtOle1-GFP and AtClo1-GFP expressing cells were analyzed using immunoblot (A) with antibodies specific for heterologous protein (anti-GFP), Golgi/endosome (anti-Pep1), plasma membrane (anti ...
Tamazight Cherifi (457112) +5 more
core +1 more source
Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model
FEBS Open Bio, EarlyView.This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito +7 more
wiley +1 more source
Data underlying Chapter 4 of the PhD thesis of Mengwei Li (Utrecht University), "Lipid-Mediated Control of Thermally Induced Shape Transformations in Liquid Crystal Droplets". Samples.
Tran, Lisa, Li, Mengwei
core +1 more source
Evolution‐guided yeast complementation reveals functional differences in human PSPH variants
FEBS Open Bio, EarlyView.Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez +6 more
wiley +1 more source
FEBS Open Bio, EarlyView.We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen +5 more
wiley +1 more source