Results 41 to 50 of about 863,741 (256)
The Phospholipid:Diacylglycerol Acyltransferase Lro1 Is Responsible for Hepatitis C Virus Core-Induced Lipid Droplet Formation in a Yeast Model System. [PDF]
PLoS ONE, 2016 Chronic infection with the hepatitis C virus frequently induces steatosis, which is a significant risk factor for liver pathogenesis. Steatosis is characterized by the accumulation of lipid droplets in hepatocytes.
Shingo Iwasa +7 more
doaj +1 more source
Metastatic niche shaped by host factors influences disseminated cancer cell fate
FEBS Letters, EarlyView.Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
Potential applications of lipid droplets from marine plants and microalgae in food and health
Food Chemistry AdvancesLipid droplets serve as an essential storage energy, well known to exist in plants. Lipid droplets have been observed in seagrass, diatoms, and microalgae.
Buntora Pasaribu +14 more
doaj +1 more source
, 2018 (A) Lipid droplets stained by ORO in NCR, HCARDA and ½ HCARDA + ½ OO. Only cells isolated from the testicles of the HCARDA experimental condition showed more than one drop. Magnification: 620X.
María E. Cabrillana (289205) +6 more
core +1 more source
Smaller is better: nanobodies meet NMR
FEBS Letters, EarlyView.Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley +1 more source
Particle size distribution of lipid droplets in experimental diets.
, 2023 Particle size distribution of lipid droplets in experimental diets.
Lidewij Schipper (4103800) +4 more
core +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Important advances in the knowledge of lipid droplets in the last six decades
, 2019 Lipid droplets are highly dynamic cytoplasmic (and nuclear) cell organelles composed of a core of neutral lipids (triglycerides (TG) and cholesterol ester (CE)) surrounded by a monolayer of phospholipids with embedded proteins.
Catala, Angel
core +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Lipid droplet-associated proteins: Roles in cardiovascular diseases
Journal of Lipid ResearchCardiovascular diseases (CVDs) are among the leading causes of morbidity and mortality worldwide. In the cardiovascular system, lipids serve as a primary energy source, and dysregulated lipid metabolism has been observed in many CVDs. Lipid droplets (LDs)
Zhongyang Yu +4 more
doaj +1 more source