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INTRODUCTION: With cellular lipid storage varying, the balance between lipid intake and lipid degradation was a must to keep healthy and determined the level of lipid droplets. Although lipid droplets accumulation had been well demonstrated in adipocytes,
Xia Yi +6 more
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New partner for mitochondria: lipid droplets under the splitGFP fluorescence
reservedIl progetto di tesi si basa sull'analisi di connessioni funzionali tra mitocondri e gocce lipidiche (lipid droplets), mediante l'ottenimento di dati basati sulla fluorescenza emessa dalla Superfolder GFP trattata con il sistema SPLICS. Nella tesi
DONÒ, GIANLUCA
core
Lipid droplets in the nervous system: involvement in cell metabolic homeostasis
Lipid droplets serve as primary storage organelles for neutral lipids in neurons, glial cells, and other cells in the nervous system. Lipid droplet formation begins with the synthesis of neutral lipids in the endoplasmic reticulum.
Yuchen Zhang +5 more
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Lipid droplets as ubiquitous fat storage organelles in
Background Lipid droplets are a class of eukaryotic cell organelles for storage of neutral fat such as triacylglycerol (TAG) and cholesterol ester (CE).
Guo Fengli +3 more
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Lipid droplets (LDs) are intracellular organelles with a hydrophobic core formed by neutral lipids surrounded by a phospholipid monolayer harboring a variety of regulatory and enzymatically active proteins. Over the last few decades, our understanding of LD biology has evolved significantly.
Michele Wölk, Maria Fedorova
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Lipid droplets in stress protection: distinct mechanisms of lipid droplet microautophagy
Lipid droplets (LDs) are organelles that function as sites for lipid storage. LDs have also been implicated in the cellular response to proteotoxic or lipotoxic stress as sites for sequestering dysfunctional or excess proteins or lipids, and targeting those cargos for degradation by LD microautophagy (microlipophagy, μLP).
Pin-Chao Liao, Liza A. Pon
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Expanding Roles for Lipid Droplets [PDF]
Lipid droplets are the intracellular sites for neutral lipid storage. They are critical for lipid metabolism and energy homeostasis, and their dysfunction has been linked to many diseases. Accumulating evidence suggests that the roles lipid droplets play
Welte, Michael A.
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Lipid droplets have emerged as dynamic organelles involved in diverse cellular processes beyond simple lipid storage. In plants and cyanobacteria, growing evidence highlights their importance in stress adaptation and signaling, yet methods to study their
Febri Susanto +2 more
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Application of synthetic lipid droplets in metabolic diseases
Background The study and synthesis of membrane organelles are becoming increasingly important, not only as simplified cellular models for corresponding molecular and metabolic studies but also for applications in synthetic biology of artificial cells and
Pengxiang Zhao +6 more
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Lipid droplets are the major organelles for fat storage in a cell and analyzing lipid droplets in Caenorhabditis elegans (C. elegans) can shed light on obesity-related diseases in humans.
Ruijie Shi +7 more
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