Results 111 to 120 of about 333,930 (355)

Soluble epoxide hydrolase derived lipid mediators are elevated in bronchoalveolar lavage fluid from patients with sarcoidosis: a cross-sectional study

Respiratory Research, 2018
Background Sarcoidosis is a systemic inflammatory multi-organ disease almost always affecting the lungs. The etiology remains unknown, but the hallmark of sarcoidosis is formation of non-caseating epithelioid cells granulomas in involved organs.
Marcus O. D. Sjödin, Antonio Checa, Mingxing Yang, Sven-Erik Dahlén, Åsa M. Wheelock, Anders Eklund, Johan Grunewald, Craig E. Wheelock   +7 more
doaj   +1 more source

Molecular mechanisms regulating perivascular adipose tissue - potential pharmacological targets? [PDF]

, 2017
No abstract ...
Kennedy, Simon, Salt, Ian P.
core   +1 more source

Lipid Mediators in Life Science

Experimental Animals, 2011
"Lipid mediators" represent a class of bioactive lipids that are produced locally through specific biosynthetic pathways in response to extracellular stimuli. They are exported extracellularly, bind to their cognate G protein-coupled receptors (GPCRs) to transmit signals to target cells, and are then sequestered rapidly through specific enzymatic or ...
openaire   +3 more sources

Dietary nitrate and nitrite protect against doxorubicin‐induced cardiac fibrosis and oxidative protein damage in tumor‐bearing mice

FEBS Open Bio, EarlyView.
Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani, Xiaofei Chen, Nildris Cruz‐Diaz, Xuewei Zhu, Swati Basu, Daniel B. Kim‐Shapiro, David R. Soto‐Pantoja, Leslie B. Poole   +7 more
wiley   +1 more source

Eicosanoid production by Candida parapsilosis and other pathogenic yeasts

Virulence, 2019
Eicosanoids are bioactive lipid mediators generated in almost all mammalian cells from the oxidation of arachidonic acid and other related twenty-carbon polyunsaturated fatty acids (PUFA).
Tanmoy Chakraborty, Renáta Tóth, Attila Gácser   +2 more
doaj   +1 more source

Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice

FEBS Open Bio, EarlyView.
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp, Eszter Kozák, Natália Tőkési, Lilian Kocsis, Anikó Kelemen, Zsuzsanna Geszti, Adriána Kutás, Mariann Harangi, Ágnes Diószegi, Zsolt Rapi, József Balla, Olivier Le Saux, András Váradi, Viola Pomozi   +13 more
wiley   +1 more source

Mast cells as the strength of the inflammatory process

Polish Journal of Pathology, 2017
The inflammatory process is a complex host defence mechanism aimed at the elimination of deleterious factors disturbing homeostasis. Inflammation consists of several interdependent stages controlled by a wide range of mediators. Those include acute phase
Joanna Pastwińska, Justyna Agier, Jarosław Dastych, Ewa Brzezińska-Błaszczyk   +3 more
doaj   +1 more source

Recombinant gamma interferon induces hypertriglyceridemia and inhibits post-heparin lipase activity in cancer patients. [PDF]

, 1986
Animals suffering from malignancy or chronic infection develop characteristic metabolic abnormalities, including a well-defined hypertriglyceridemic state.
Bradley, WA, Gianturco, SH, Gutterman, JU, Kurzrock, R, Quesada, JR, Rohde, MF, Sherwin, SA   +6 more
core  

The Effect of Krill Oil Supplementation on Exercise Performance and Markers of Immune Function [PDF]

, 2015
Date of Acceptance: 08/09/2015 Acknowledgments We thank the technical support of the Institute of Medical Sciences Musculoskeletal Programme and the Iain Fraser Cytometry Centre.Peer reviewedPublisher ...
Brazaite, Goda, Da Boit, Mariasole, Gray, Stuart Robert, Mastalurova, Ina, McGovern, Niall, Thompson, Keith   +5 more
core   +5 more sources

Osthole improves glucose and lipid metabolism via modulation of PPARα/γ-mediated target gene expression in liver, adipose tissue, and skeletal muscle in fatty liver rats [PDF]

, 2015
Zhigang Qi, Xi Zhao, Wen Zhong, Mei-Lin Xie   +3 more
openalex   +1 more source