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Special Issue on “Sphingolipids: From Pathology to Therapeutic Perspectives”

open access: yesCells, 2020
It is an honor for us to dedicate this Special Issue to our dearest friend Lina Obeid, who was not only a pioneer in the field of sphingolipids, but also a remarkable personality [...]
Gerhild van Echten-Deckert
doaj   +1 more source

Onsager’s variational principle in soft matter : introduction and application to the dynamics of adsorption of proteins onto fluid membranes [PDF]

open access: yes, 2018
This book is the first collection of lipid-membrane research conducted by leading mechanicians and experts in continuum mechanics. It brings the overall intellectual framework afforded by modern continuum mechanics to bear on a host of challenging ...
Arroyo Balaguer, Marino   +3 more
core   +2 more sources

Membrane lipids and their degradation compounds control GM2 catabolism at intralysosomal luminal vesicles

open access: yesJournal of Lipid Research, 2019
The catabolism of ganglioside GM2 is dependent on three gene products. Mutations in any of these genes result in a different type of GM2 gangliosidosis (Tay-Sachs disease, Sandhoff disease, and the B1 and AB variants of GM2 gangliosidosis), with GM2 as ...
Susi Anheuser   +2 more
doaj   +1 more source

Lipids and membranes [PDF]

open access: yesFEBS Letters, 1974
Today, as in 1964, those who are concerned with membranes are broadly divided into two main groups: investigators who work on lipids and others who study proteins. Whether one pursues mainly this aspect or that is often more the result of individual interest and background rather than the outcome of a decision that one particular aspect of membranes is
openaire   +2 more sources

Mechanisms and functions of membrane lipid remodeling in plants.

open access: yesThe Plant Journal, 2021
Lipid remodeling, defined herein as post-synthetic structural modifications of membrane lipids, play crucial roles in regulating the physicochemical properties of cellular membranes and hence their many functions.
Linhui Yu   +4 more
semanticscholar   +1 more source

When Is a Reaction Network a Metabolism? Criteria for Simple Metabolisms That Support Growth and Division of Protocells

open access: yesLife, 2021
With the aim of better understanding the nature of metabolism in the first cells and the relationship between the origin of life and the origin of metabolism, we propose three criteria that a chemical reaction system must satisfy in order to constitute a
Paul G. Higgs
doaj   +1 more source

Lateral phase separation in mixtures of lipids and cholesterol [PDF]

open access: yes, 2004
In an effort to understand "rafts" in biological membranes, we propose phenomenological models for saturated and unsaturated lipid mixtures, and lipid-cholesterol mixtures.
Bloom M.   +16 more
core   +2 more sources

Biointerfacial self-assembly generates lipid membrane coated bacteria for enhanced oral delivery and treatment

open access: yesNature Communications, 2019
The gut microbiota represents a huge community of microorganisms that play essential roles in immune modulation and homeostasis maintenance. Microbiota transplantation is an important approach to prevent and treat disease as it can inhibit pathogen ...
Zhenping Cao   +4 more
semanticscholar   +1 more source

Membrane lipids regulate ganglioside GM2 catabolism and GM2 activator protein activity[S]

open access: yesJournal of Lipid Research, 2015
Ganglioside GM2 is the major lysosomal storage compound of Tay-Sachs disease. It also accumulates in Niemann-Pick disease types A and B with primary storage of SM and with cholesterol in type C.
Susi Anheuser   +3 more
doaj   +1 more source

Physical Concept to Explain the Regulation of Lipid Membrane Phase Separation under Isothermal Conditions

open access: yesLife, 2023
Lateral phase separation within lipid bilayer membranes has attracted considerable attention in the fields of biophysics and cell biology. Living cells organize laterally segregated compartments, such as raft domains in an ordered phase, and regulate ...
Naofumi Shimokawa, Tsutomu Hamada
doaj   +1 more source

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