Results 31 to 40 of about 4,092,639 (351)

Partial synthesis of ganglioside and lysoganglioside lipoforms as internal standards for MS quantification

open access: yesJournal of Lipid Research, 2014
Within recent years, ganglioside patterns have been increasingly analyzed by MS. However, internal standards for calibration are only available for gangliosides GM1, GM2, and GM3.
Martin Gantner   +3 more
doaj   +1 more source

Novel African trypanocidal agents: membrane rigidifying peptides [PDF]

open access: yes, 2012
The bloodstream developmental forms of pathogenic African trypanosomes are uniquely susceptible to killing by small hydrophobic peptides. Trypanocidal activity is conferred by peptide hydrophobicity and charge distribution and results from increased ...
Andreas Hartel   +8 more
core   +3 more sources

LimeSeg: a coarse-grained lipid membrane simulation for 3D image segmentation

open access: yesBMC Bioinformatics, 2019
3D segmentation is often a prerequisite for 3D object display and quantitative measurements. Yet existing voxel-based methods do not directly give information on the object surface or topology.
Sarah Machado   +2 more
semanticscholar   +1 more source

Lipids regulate the hydrolysis of membrane bound glucosylceramide by lysosomal β-glucocerebrosidase

open access: yesJournal of Lipid Research, 2017
Glucosylceramide (GlcCer) is the primary storage lipid in the lysosomes of Gaucher patients and a secondary one in Niemann-Pick disease types A, B, and C.
Misbaudeen Abdul-Hammed   +3 more
doaj   +1 more source

Plasmon Waveguide Resonance: Principles, Applications and Historical Perspectives on Instrument Development

open access: yesMolecules, 2021
Plasmon waveguide resonance (PWR) is a variant of surface plasmon resonance (SPR) that was invented about two decades ago at the University of Arizona.
Estelle Rascol   +3 more
doaj   +1 more source

Lipid membrane-mediated attraction between curvature inducing objects [PDF]

open access: yesScientific Reports, 2016
The interplay of membrane proteins is vital for many biological processes, such as cellular transport, cell division, and signal transduction between nerve cells.
Casper van der Wel   +5 more
semanticscholar   +1 more source

Acid sphingomyelinase activity is regulated by membrane lipids and facilitates cholesterol transfer by NPC2[S]

open access: yesJournal of Lipid Research, 2014
During endocytosis, membrane components move to intraluminal vesicles of the endolysosomal compartment for digestion. At the late endosomes, cholesterol is sorted out mainly by two sterol-binding proteins, Niemann-Pick protein type C (NPC)1 and NPC2.
Vincent O. Oninla   +3 more
doaj   +1 more source

Membrane-spanning lipids for an uncompromised monitoring of membrane fusion and intermembrane lipid transfer

open access: yesJournal of Lipid Research, 2015
A Förster resonance energy transfer-based fusion and transfer assay was developed to study, in model membranes, protein-mediated membrane fusion and intermembrane lipid transfer of fluorescent sphingolipid analogs.
Günter Schwarzmann   +2 more
doaj   +1 more source

Hydrophobic Mismatch Controls the Mode of Membrane-Mediated Interactions of Transmembrane Peptides

open access: yesMembranes, 2022
Various cellular processes require the concerted cooperative action of proteins. The possibility for such synchronization implies the occurrence of specific long-range interactions between the involved protein participants.
Oleg V. Kondrashov   +2 more
doaj   +1 more source

Coupling between pore formation and phase separation in charged lipid membranes [PDF]

open access: yes, 2015
We investigated the effect of charge on the membrane morphology of giant unilamellar vesicles (GUVs) composed of various mixtures containing charged lipids.
Hamada, Tsutomu   +5 more
core   +2 more sources

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