Results 91 to 100 of about 103,596 (298)

Triglyceride mobilization from lipid droplets sustains the anti-steatotic action of iodothyronines in cultured rat hepatocytes.

Frontiers in Physiology, 2016
Adipose tissue, dietary lipids and de novo lipogenesis are sources of hepatic fatty acids (FFAs) that are stored in lipid droplets (LDs) as triacylglycerols (TAGs). Destiny of TAGs stored in LDs is determined by LD proteomic equipment.
Elena eGrasselli, Elena eGrasselli, Adriana eVoci, Ilaria eDemori, Giulia eVecchione, Andrea D Compalati, Gabriella eGallo, Fernando eGoglia, Rita eDe Matteis, Elena eSilvestri, Laura eVergani, Laura eVergani   +11 more
doaj   +1 more source

Baseline and Stress-Induced Plasma Corticosterone during Long-Distance Migration in the Bar-Tailed Godwit, Limosa lapponica [PDF]

, 2002
The specific roles of corticosterone in promotion of avian migration remain unclear even though this glucocorticosteroid is elevated in many migrating bird species.
Jukema, Joop,, Landys-Ciannelli, Mėta M.,, Piersma, Theunis,, Ramenofsky, Marilyn,, Wijker, Arnold,, Wingfield, John C.,   +5 more
core   +3 more sources

Tumor‐Induced Splenic Remodeling: Mechanisms of Systemic Immunosuppression and Emerging Therapeutic Opportunities

Advanced Science, EarlyView.
ABSTRACT Despite the transformative impact of cancer immunotherapies such as immune checkpoint blockade, durable clinical responses remain limited. Increasing evidence indicates that antitumor immunity is governed not only by the tumor microenvironment, but also by systemic immune regulation mediated by peripheral immune organs. Among these, the spleen
Yuehua Liu, Xiaoqian Nie, Xiaofei Gao
wiley   +1 more source

Lipid droplet formation on opposing sides of the endoplasmic reticulum

Journal of Lipid Research, 2012
In animal cells, the primary repositories of esterified fatty acids and alcohols (neutral lipids) are lipid droplets that form on the lumenal and/or cytoplasmic side of the endoplasmic reticulum (ER) membrane.
Stephen L. Sturley, M. Mahmood Hussain
doaj   +1 more source

Trophic upgrading and mobilization of wax esters in microzooplankton [PDF]

, 2019
Heterotrophic protists play pivotal roles in aquatic ecosystems by transferring matter and energy, including lipids, from primary producers to higher trophic predators.
D\u27souza, Nigel, Haubrich, Brad A, Mantalbano, Amanda, Menden-Deuer, Susanne, Reid, Christopher, Roohani, Keyana, Rynearson, Tatiana, Yue, Kai-Lou   +7 more
core   +3 more sources

A Genomic Catalog of Migratory Microbiomes from Wild Birds across China's Habitats

Advanced Science, EarlyView.
ABSTRACT Migratory birds play an important role in the spread of antimicrobial resistance (AMR); however, gaps in surveillance data from vital regions along migratory flyways across China limit the detection of emergent threats. Here, we assembled 340 metagenomes from 52 bird species covering 11 provincial administrative districts in China, presenting ...
Yanan Wang, Heqi Wu, Mengqi Qu, Chunge Zhang, Ziqian Xu, Yuhang Pei, Chaochao Zhao, Jiangtao Wang, Sufang Ma, Na Lyu, Xuebin Xu, Yuhai Bi, Baoli Zhu, George F. Gao   +13 more
wiley   +1 more source

RABC1-ABI1 module coordinates lipid droplet mobilization and post-germination growth arrest in Arabidopsis

Cell Reports
Summary: Abscisic acid (ABA) promotes post-germination growth arrest (PGGA), thereby enhancing plant survival under adverse conditions such as high salinity.
Yifei Wang, Min Zhang, Pengyue Sun, Xin Zhao, Ruo-Xi Zhang, Yun-Kuan Liang   +5 more
doaj   +1 more source

Subverting sterols: rerouting an oxysterol-signaling pathway to promote tumor growth. [PDF]

, 2013
Oxysterols are oxidized derivatives of cholesterol that are generated enzymatically or through autoxidation. Initially identified as important lipid signaling molecules in the context of atherosclerosis and inflammation, accumulated evidence indicates ...
Bensinger, Steven J, York, Autumn G
core   +1 more source

Biomimetic Bone Marrow Monocyte Membrane‐Fused Extracellular Vesicles for Targeted Therapy of Myocardial Infarction

Advanced Science, EarlyView.
This study develops a biomimetic delivery system (M‐hEV) by fusing monocyte membranes with extracellular vesicles for targeted therapy of damaged cardiac tissue. The system homes to injured myocardium through specific molecular pathways. In a myocardial infarction model, M‐hEV effectively accumulates in the heart, reduces infarct size, alleviates ...
Jiaxin Song, Hao Yang, Qiqi Zhang, Wenqin Zhou, Rui Wang, Yuxing Xie, Emeli Chatterjee, Guoping Li, Jizong Jiang, Qiulian Zhou, Cuimei Zhao   +10 more
wiley   +1 more source

Clinical Insights From a Case of Sifrim‐Hitz‐Weiss Syndrome With a CHD4 Variant: Expanding the Phenotypic Spectrum and Its Response to Growth Hormone Therapy

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT To enhance clinicians' understanding of Sifrim‐Hitz‐Weiss syndrome (SIHIWES), this study investigated the clinical phenotypes, genetic characteristics, and response to growth hormone therapy in a patient. A case of a patient with global developmental delay and distinctive facial features is presented.
Jianmei Zhang, Shuangzhong Chen, Guanping Dong, Suhong Yang, Ping Wang, Qiong Zhou, Pingping Wang   +6 more
wiley   +1 more source