Results 121 to 130 of about 47,375 (257)

Dropping in on Lipid Mobilization From the Gut. [PDF]

open access: yesCell Mol Gastroenterol Hepatol, 2019
Davidson NO.
europepmc   +1 more source

Retatrutide Shows Multiple Metabolic Benefits in Diet‐Induced Obese MASH Mouse and Hamster Models

open access: yesObesity, EarlyView.
ABSTRACT Objective/Methods Our aim was to evaluate the efficacy of the triple glucagon, GIP, and GLP‐1 receptor agonist retatrutide in diet‐induced obese MASH mouse and hamster models, two preclinical models that we routinely use for assessing new therapies targeting obesity.
François Briand   +6 more
wiley   +1 more source

Joint TOS/OMA/OAC Expert Guidance Statement on the Pharmacological Management of United States Adults With Overweight or Obesity Using the GRADE Approach

open access: yesObesity, EarlyView.
Guidance recommendations by TOS/OMA/OAC for the use of obesity medications to treat obesity and its complications. ABSTRACT Background Obesity affects over 40% of US adults, with severe obesity on the rise. Despite recognition of obesity as a chronic disease, it remains underdiagnosed and undertreated.
Lydia Alexander   +12 more
wiley   +1 more source

TMEM41B is a novel regulator of autophagy and lipid mobilization. [PDF]

open access: yesEMBO Rep, 2018
Moretti F   +20 more
europepmc   +1 more source

Nigericin‐Triggered Phosphodynamics in Inflammasome Formation and Pyroptosis

open access: yesPROTEOMICS, EarlyView.
ABSTRACT Innate immune signaling relies heavily on phosphorylation cascades to mount effective immune responses. Although traditional innate immune signaling cascades following TLR4 stimulation have been investigated through a temporally quantitative phosphoproteomic lens, far fewer studies have applied these methods to distinct signaling following the
Vanya Bhushan   +5 more
wiley   +1 more source

Transcriptional determinants of lipid mobilization in human adipocytes. [PDF]

open access: yesSci Adv
Ludzki AC   +21 more
europepmc   +1 more source

Nutritional properties, traditional uses and potential new applications for the sotol plant (Asparagaceae, Convallarioideae): A review

open access: yesPLANTS, PEOPLE, PLANET, EarlyView.
Sotol (Dasylirion spp.) is a resilient desert plant that sustains ecosystems, cultures and livelihoods in Chihuahua Desert. Our review highlights its nutritional properties, traditional uses and potential new applications in food, pharmaceuticals, renewable energy and water remediation. By synthesizing evidence across disciplines, we show how sotol can
Dámaris Leopoldina Ojeda Barrios   +7 more
wiley   +1 more source

Wnt/Wingless signaling promotes lipid mobilization through signal-induced transcriptional repression. [PDF]

open access: yesProc Natl Acad Sci U S A
Liu M   +7 more
europepmc   +1 more source

Genetically modified mouse models to study hepatic neutral lipid mobilization. [PDF]

open access: yesBiochim Biophys Acta Mol Basis Dis, 2019
Haemmerle G, Lass A.
europepmc   +1 more source

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