Results 151 to 160 of about 103,596 (298)

Iron Fertilization of Soybean Genotypes Differing in Iron Use Efficiency Under Alkaline Conditions: Implications for Yield and Seed Nutritional Quality

Journal of Plant Nutrition and Soil Science, EarlyView.
ABSTRACT Background Soybean, a nutritionally important protein‐ and oil‐rich legume, is highly sensitive to iron (Fe) deficiency under alkaline conditions, where reduced Fe availability limits growth, yield, and seed quality. Effective biofortification therefore requires increasing seed Fe while reducing phytate that restricts Fe bioavailability.
Amir Maqbool, Ramazan Ilhan Aytekin, Sevgi Çalişkan, Emre Aksoy   +3 more
wiley   +1 more source

SIRT3 Acts as a Positive Autophagy Regulator to Promote Lipid Mobilization in Adipocytes via Activating AMPK. [PDF]

Int J Mol Sci, 2020
Zhang T, Liu J, Tong Q, Lin L.
europepmc   +1 more source

Selenium biofortification of pea (Pisum sativum L.) microgreens through seed priming: Effects on agronomic performance and nutritional quality

Journal of the Science of Food and Agriculture, EarlyView.
Abstract BACKGROUND Selenium (Se) deficiency is a widespread nutritional problem. Agronomic biofortification of microgreens through seed nutripriming is a promising approach to enhance Se intake. Microgreens, comprising nutrient‐dense foods that can be produced year‐round, are ideal targets for biofortification and may help alleviate malnutrition. This
Cátia Magalhães, Matilde Rodrigues, José Pinela   +2 more
wiley   +1 more source

Dexamphetamine and lipid mobilization in obesity

Journal of Pharmacy and Pharmacology, 1964
R, SANTI, G, FASSINA
openaire   +2 more sources

Restoration of Immune Surveillance in Prostate Cancer Prevention by Sulforaphane in Hi‐Myc Mice

Molecular Carcinogenesis, EarlyView.
ABSTRACT Oral administration of broccoli constituent sulforaphane (SFN) prevents prostate cancer development in preclinical mouse models. However, the mechanism(s) underlying prostate cancer prevention by SFN are not fully understood. In this study, we used a human relevant mouse model (Hi‐Myc mice) to demonstrate restoration of immune surveillance by ...
Krishna B. Singh, Eun‐Ryeong Hahm, Joshi J. Alumkal, Shivendra V. Singh   +3 more
wiley   +1 more source

Circadian Immunity and Vascular Inflammation in Cardiovascular Disease Chronotherapy Windows: Time for a Re‐Assessment

Med Research, EarlyView.
ABSTRACT Circadian rhythms orchestrate cardiovascular physiology by regulating immune and inflammatory pathways. Disruption of these rhythms profoundly alters vascular homeostasis, thereby promoting the onset and progression of cardiovascular diseases (CVD).
Tian Zhang, Ge Zhang, Tian‐Ding Liu, Tianshu Gu, Fengyi Yu, Pengyuan Xu, Wunan Mi, Xuanjiang Zhao, Qian Guo, Honglin Zheng, Taiqi Zhao, Qiang Li, Di Lu, Mingxuan Duan, Chaoyang Yu, Ruhao Wu, Shiqian Zhang, Haonan Zhang, Zeyu Wang, Youyang Zheng, Yan Xiao, Zenglei Zhang, Ge Zhang   +22 more
wiley   +1 more source

Multi‐Targeting Ligands as Prospective Therapeutics for Alzheimer's Disease, a Prevalent Neurodegenerative Disorder: Mechanistic Insights, Emerging Targets and Drug Discovery Campaigns

Medicinal Research Reviews, EarlyView.
ABSTRACT Alzheimer's disease (AD) is a debilitating neurodegenerative condition characterized by progressive cognitive impairment, memory deterioration, and neuronal dysfunction. Its complex pathophysiology involves multiple interlinked processes, including amyloid‐β (Aβ) aggregation, tau hyperphosphorylation, oxidative stress, neuroinflammation ...
Amandeep Thakur, Mandeep Rana, Sakshi Vanjani, Kei‐Chi Liou, Rajeev Taliyan, Kunal Nepali, Chih‐Hao Yang   +6 more
wiley   +1 more source

Systematic analyses of lipid mobilization by human lipid transfer proteins. [PDF]

Nature
Titeca K, Chiapparino A, Hennrich ML, Türei D, Moqadam M, Talandashti R, Cuveillier C, van Ek L, Zukowska J, Triana S, Echelard F, Nielsen IØ, Foged MM, Gehin C, Olechnovic K, Grudinin S, Saez-Rodriguez J, Alexandrov T, Maeda K, Reuter N, Gavin AC.   +20 more
europepmc   +1 more source

Retatrutide Shows Multiple Metabolic Benefits in Diet‐Induced Obese MASH Mouse and Hamster Models

Obesity, EarlyView.
ABSTRACT Objective/Methods Our aim was to evaluate the efficacy of the triple glucagon, GIP, and GLP‐1 receptor agonist retatrutide in diet‐induced obese MASH mouse and hamster models, two preclinical models that we routinely use for assessing new therapies targeting obesity.
François Briand, Camille Le Cudennec, Estelle Grasset, Natalia Breyner, Claire Bigot, Pierre Dillard, Thierry Sulpice   +6 more
wiley   +1 more source

Nigericin‐Triggered Phosphodynamics in Inflammasome Formation and Pyroptosis

PROTEOMICS, EarlyView.
ABSTRACT Innate immune signaling relies heavily on phosphorylation cascades to mount effective immune responses. Although traditional innate immune signaling cascades following TLR4 stimulation have been investigated through a temporally quantitative phosphoproteomic lens, far fewer studies have applied these methods to distinct signaling following the
Vanya Bhushan, Clinton J. Bradfield, Sandhini Saha, Sung Hwan Yoon, Iain D. C. Fraser, Aleksandra Nita‐Lazar   +5 more
wiley   +1 more source