Results 11 to 20 of about 117,691 (310)

From Bench to Bedside: Implications of Lipid Nanoparticle Carrier Reactogenicity for Advancing Nucleic Acid Therapeutics

Pharmaceuticals, 2023
In biomedical applications, nanomaterial-based delivery vehicles, such as lipid nanoparticles, have emerged as promising instruments for improving the solubility, stability, and encapsulation of various payloads.
Tetiana Korzun, Abraham S. Moses, Parham Diba, Ariana L. Sattler, Olena R. Taratula, Gaurav Sahay, Oleh Taratula, Daniel L. Marks   +7 more
doaj   +1 more source

Lipid Polymeric Hybrid Nanoparticles: Formulation Techniques and Effects on Glioblastoma [PDF]

Pharmaceutical Sciences, 2022
In the pharmaceutical industry, liposomes and polymeric nanoparticles are the two most commonly studied delivery vehicles. A new technique uses lipid-polymeric hybrid nanoparticles (LPHNPs) with a polymeric core, and a shell made up of lipid-lipid-PEG ...
Yudhishtir Singh Baghel, Sankha Bhattacharya   +1 more
doaj   +1 more source

LIPID AND SILVER NANOPARTICLES GELS FORMULATION OF TEMPEH EXTRACT

Jurnal Farmasi Sains dan Komunitas, 2020
Tempeh extract is used in this study as an active ingredient in lipid nanoparticles and reductant in silver nanoparticles because tempeh is an authentic Indonesian food ingredient and is known to have the main content of isoflavones.
Felicia Satya Christania, Rini Dwiastuti, Sri Hartati Yuliani   +2 more
doaj   +1 more source

Lipid Nanoparticles for the Posterior Eye Segment

Pharmaceutics, 2021
This review highlights the application of lipid nanoparticles (Solid Lipid Nanoparticles, Nanostructured Lipid Carriers, or Lipid Drug Conjugates) as effective drug carriers for pathologies affecting the posterior ocular segment. Eye anatomy and the most
Lorena Bonilla, Marta Espina, Patricia Severino, Amanda Cano, Miren Ettcheto, Antoni Camins, Maria Luisa García, Eliana B. Souto, Elena Sánchez-López   +8 more
doaj   +1 more source

Preclinical Evaluation of Lipid-Based Nanosystems

Pharmaceutics, 2021
The use of lipid-based nanosystems, including lipid nanoparticles (solid lipid nanoparticles—SLN, and nanostructured lipid carriers—NLC), nanoemulsions, and liposomes, among others, is widespread [...]
Ana Catarina Silva, José Manuel Sousa Lobo   +1 more
doaj   +1 more source

Editorial—Current Insights on Lipid-Based Nanosystems

Pharmaceuticals, 2022
Lipid-based nanosystems, including solid lipid nanoparticles (SLN) and nanostructured lipid carriers (NLC), cationic lipid nanoparticles, nanoemulsions and liposomes, have been extensively studied to improve drug delivery through different administration
Ana Catarina Silva, João Nuno Moreira, José Manuel Sousa Lobo   +2 more
doaj   +1 more source

Computer Simulations of Lipid Nanoparticles [PDF]

Nanomaterials, 2017
Lipid nanoparticles (LNP) are promising soft matter nanomaterials for drug delivery applications. In spite of their interest, little is known about the supramolecular organization of the components of these self-assembled nanoparticles. Here, we present a molecular dynamics simulation study, employing the Martini coarse-grain forcefield, of self ...
Xavier Fernandez-Luengo, Juan Camacho, Jordi Faraudo   +2 more
openaire   +5 more sources

Use of Microfluidics to Prepare Lipid-Based Nanocarriers

Pharmaceutics, 2023
Lipid-based nanoparticles (LBNPs) are an important tool for the delivery of a diverse set of drug cargoes, including small molecules, oligonucleotides, and proteins and peptides. Despite their development over the past several decades, this technology is
Alicia Vogelaar, Samantha Marcotte, Jiaqi Cheng, Benazir Oluoch, Jennica Zaro   +4 more
doaj   +1 more source

Intranasal delivery of Odorranalectin-modified lipid nanoparticles for multi-targeted therapy of Alzheimer's disease. [PDF]

Mater Today Bio
Zhang Y, Yin C, Tian Y, Li X, Wang H, Han S, Chen H, Hou H.   +7 more
europepmc   +2 more sources

Lipid based nanoparticles as a novel treatment modality for hepatocellular carcinoma: a comprehensive review on targeting and recent advances

Journal of Nanobiotechnology, 2022
Liver cancer is considered one of the deadliest diseases with one of the highest disease burdens worldwide. Among the different types of liver cancer, hepatocellular carcinoma is considered to be the most common type. Multiple conventional approaches are
Khaled Mahmoud, Shady Swidan, Mohamed El-Nabarawi, Mahmoud Teaima   +3 more
doaj   +1 more source