Results 21 to 30 of about 112,460 (251)

Tear of lipid membranes by nanoparticles

open access: yesSoft Matter, 2022
Tear, a direct physical damage of lipid bilayers, can be inflicted by small enough nanoparticles.
Er-Rafik, Meriem   +7 more
openaire   +4 more sources

Solid Lipid Nanoparticles

open access: yesEncyclopedia, 2022
Solid lipid nanoparticles (SLNs) are produced from physiologically biocompatible lipids. They have been proven to improve solubility, cellular uptake, and stability, reduce enzyme degradation, and prolong the circulation time of various drugs.
Thi-Thao-Linh Nguyen, Van-An Duong
doaj   +1 more source

Sustained Cytotoxicity of Wogonin on Breast Cancer Cells by Encapsulation in Solid Lipid Nanoparticles

open access: yesNanomaterials, 2018
While wogonin has been known to have cytotoxicity against various cancer cells, its bioavailability and cytotoxicity are low due to its low water solubility.
Jong-Suep Baek   +2 more
doaj   +1 more source

On the Structure of Solid Lipid Nanoparticles [PDF]

open access: yesSmall, 2019
AbstractSolid lipid nanoparticles (SLNs) have a crystalline lipid core which is stabilized by interfacial surfactants. SLNs are considered favorable candidates for drug delivery vehicles since their ability to store and release organic molecules can be tailored through the identity of the lipids and surfactants used.
Demi L. Pink   +6 more
openaire   +2 more sources

Central Composite Design for Formulation and Optimization of Solid Lipid Nanoparticles to Enhance Oral Bioavailability of Acyclovir

open access: yesMolecules, 2021
Treatment of herpes simplex infection requires high and frequent doses of oral acyclovir to attain its maximum therapeutic effect. The current therapeutic regimen of acyclovir is known to cause unwarranted dose-related adverse effects, including acute ...
Haniza Hassan   +5 more
doaj   +1 more source

Ultrasmall Solid-Lipid Nanoparticles via the Polysorbate Sorbitan Phase-Inversion Temperature Technique: A Promising Vehicle for Antioxidant Delivery into the Skin

open access: yesPharmaceutics, 2023
Solid lipid nanoparticles promote skin hydration via stratum corneum occlusion, which prevents water loss by evaporation, and via the reinforcement of the skin’s lipid-film barrier, which occurs through the adhesion of the nanoparticles to the stratum ...
Francesca Della Sala   +11 more
doaj   +1 more source

Lipid-polymer hybrid nanoparticles: Development & statistical optimization of norfloxacin for topical drug delivery system

open access: yesBioactive Materials, 2017
Poly lactic acid is a biodegradable, biocompatible, and non-toxic polymer, widely used in many pharmaceutical preparations such as controlled release formulations, parenteral preparations, surgical treatment applications, and tissue engineering.
Vivek Dave   +5 more
doaj   +1 more source

Solid Lipid Nanoparticles and Nanostructured Lipid Carriers: Structure, Preparation and Application [PDF]

open access: yesAdvanced Pharmaceutical Bulletin, 2015
Lipid nanoparticles (LNPs) have attracted special interest during last few decades. Solid lipid nanoparticles (SLNs) and nanostructured lipid carriers (NLCs) are two major types of Lipid-based nanoparticles.
Neda Naseri   +2 more
doaj   +1 more source

Lipid Nanoparticles Based Cosmetics with Potential Application in Alleviating Skin Disorders

open access: yesCosmetics, 2021
The lipids mainly oils, fats, waxes and phospholipids are of substantial importance in the development and functioning of cosmetic products. The lipid nanoparticles-based cosmetic product is highly capable of protecting the skin against harmful ...
Javed Ahmad
doaj   +1 more source

Solid Lipid Nanoparticles as Innovative Carriers in Drug Delivery: A Review [PDF]

open access: yesالمجلة العراقية للصيدلة
Background: Nanoparticle technology is a new drug delivery system with nano-scale-size. The solid lipid nanoparticles are dynamic systems adopted for formulating water-soluble and insoluble drugs in a colloidal carrier.
Amal Al-Dulaimi   +2 more
doaj   +1 more source

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