Results 21 to 30 of about 128,185 (306)

Immune-Modulating Lipid Nanomaterials for the Delivery of Biopharmaceuticals

open access: yesPharmaceutics, 2023
In recent years, with the approval of preventative vaccines for pandemics, lipid nanoparticles have become a prominent RNA delivery vehicle. The lack of long-lasting effects of non-viral vectors is an advantage for infectious disease vaccines.
Songhee Kim   +3 more
doaj   +1 more source

Advances in Lipid-Based Nanoparticles for Cancer Chemoimmunotherapy

open access: yesPharmaceutics, 2021
Nanomedicines have shown great potential in cancer therapy; in particular, the combination of chemotherapy and immunotherapy (namely chemoimmunotherapy) that is revolutionizing cancer treatment.
Tianqi Wang   +5 more
doaj   +1 more source

Tear of lipid membranes by nanoparticles

open access: yesSoft Matter, 2022
Tear, a direct physical damage of lipid bilayers, can be inflicted by small enough nanoparticles.
Er-Rafik, Meriem   +7 more
openaire   +4 more sources

Computer Simulations of Lipid Nanoparticles [PDF]

open access: yesNanomaterials, 2017
Lipid nanoparticles (LNP) are promising soft matter nanomaterials for drug delivery applications. In spite of their interest, little is known about the supramolecular organization of the components of these self-assembled nanoparticles. Here, we present a molecular dynamics simulation study, employing the Martini coarse-grain forcefield, of self ...
Xavier Fernandez-Luengo   +2 more
openaire   +5 more sources

Lipid Nanoparticles Functionalized with Antibodies for Anticancer Drug Therapy

open access: yesPharmaceutics, 2023
Nanotechnology takes the lead in providing new therapeutic options for cancer patients. In the last decades, lipid-based nanoparticles—solid lipid nanoparticles (SLNs), nanostructured lipid carriers (NLCs), liposomes, and lipid–polymer hybrid ...
Ana Camila Marques   +3 more
doaj   +1 more source

From Bench to Bedside: Implications of Lipid Nanoparticle Carrier Reactogenicity for Advancing Nucleic Acid Therapeutics

open access: yesPharmaceuticals, 2023
In biomedical applications, nanomaterial-based delivery vehicles, such as lipid nanoparticles, have emerged as promising instruments for improving the solubility, stability, and encapsulation of various payloads.
Tetiana Korzun   +7 more
doaj   +1 more source

Biophysical analysis of lipidic nanoparticles [PDF]

open access: yesMethods, 2020
Biological nanoparticles include liposomes, extracellular vesicle and lipid-based discoidal systems. When studying such particles, there are several key parameters of interest, including particle size and concentration. Measuring these characteristics can be of particular importance in the research laboratory or when producing such particles as ...
Rozo, Annaïg J.   +4 more
openaire   +2 more sources

LIPID AND SILVER NANOPARTICLES GELS FORMULATION OF TEMPEH EXTRACT

open access: yesJurnal Farmasi Sains dan Komunitas, 2020
Tempeh extract is used in this study as an active ingredient in lipid nanoparticles and reductant in silver nanoparticles because tempeh is an authentic Indonesian food ingredient and is known to have the main content of isoflavones.
Felicia Satya Christania   +2 more
doaj   +1 more source

Lipid Polymeric Hybrid Nanoparticles: Formulation Techniques and Effects on Glioblastoma [PDF]

open access: yesPharmaceutical Sciences, 2022
In the pharmaceutical industry, liposomes and polymeric nanoparticles are the two most commonly studied delivery vehicles. A new technique uses lipid-polymeric hybrid nanoparticles (LPHNPs) with a polymeric core, and a shell made up of lipid-lipid-PEG ...
Yudhishtir Singh Baghel   +1 more
doaj   +1 more source

On the Structure of Solid Lipid Nanoparticles [PDF]

open access: yesSmall, 2019
AbstractSolid lipid nanoparticles (SLNs) have a crystalline lipid core which is stabilized by interfacial surfactants. SLNs are considered favorable candidates for drug delivery vehicles since their ability to store and release organic molecules can be tailored through the identity of the lipids and surfactants used.
Demi L. Pink   +6 more
openaire   +2 more sources

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