Results 11 to 20 of about 128,185 (306)

Lipid Nanoparticles for Drug Delivery [PDF]

open access: yesAdvanced NanoBiomed Research, 2022
Lipid nanoparticles have attracted significant interests in the last two decades, and have achieved tremendous clinical success since the first clinical approval of Doxil in 1995.
Letao Xu   +5 more
doaj   +5 more sources

Nebulized lipid nanoparticles [PDF]

open access: yesNature Reviews Materials, 2021
An article in Nature Biomedical Engineering reports an in vivo workflow for the design of lipid nanoparticles to efficiently deliver mRNA to the lungs via nebulization.
Christine Horejs, Horejs Christine
exaly   +3 more sources

Solid Lipid Nanoparticles vs. Nanostructured Lipid Carriers: A Comparative Review [PDF]

open access: yesPharmaceutics, 2023
Solid–lipid nanoparticles and nanostructured lipid carriers are delivery systems for the delivery of drugs and other bioactives used in diagnosis, therapy, and treatment procedures. These nanocarriers may enhance the solubility and permeability of drugs,
Cláudia Viegas   +5 more
doaj   +2 more sources

Lipid Nanoparticles for the Posterior Eye Segment [PDF]

open access: yesPharmaceutics, 2021
This review highlights the application of lipid nanoparticles (Solid Lipid Nanoparticles, Nanostructured Lipid Carriers, or Lipid Drug Conjugates) as effective drug carriers for pathologies affecting the posterior ocular segment. Eye anatomy and the most
Lorena Bonilla   +8 more
doaj   +5 more sources

Lipid nanoparticles for mRNA delivery [PDF]

open access: yesNature Reviews Materials, 2021
Messenger RNA (mRNA) has emerged as a new category of therapeutic agent to prevent and treat various diseases. To function in vivo, mRNA requires safe, effective and stable delivery systems that protect the nucleic acid from degradation and that allow cellular uptake and mRNA release.
Xucheng Hou, Tal Zaks, Robert Langer
exaly   +3 more sources

Ternary nanoparticles composed of cationic solid lipid nanoparticles, protamine, and DNA for gene delivery

open access: yesInternational Journal of Nanomedicine, 2013
Sai-Nan He,1 Yun-Long Li,1,2 Jing-Jing Yan,2 Wei Zhang,2 Yong-Zhong Du,2 He-Yong Yu,1 Fu-Qiang Hu,2 Hong Yuan21Women’s Hospital, 2College of Pharmaceutical Sciences, School of Medicine, Zhejiang University, Hangzhou, People’s Republic of ...
He SN   +6 more
doaj   +1 more source

Lipid-Based Nanoparticles in the Clinic and Clinical Trials: From Cancer Nanomedicine to COVID-19 Vaccines

open access: yesVaccines, 2021
COVID-19 vaccines have been developed with unprecedented speed which would not have been possible without decades of fundamental research on delivery nanotechnology.
Thai Thanh Hoang Thi   +5 more
doaj   +3 more sources

Solid Lipid Nanoparticles

open access: yesEncyclopedia, 2022
Solid lipid nanoparticles (SLNs) are produced from physiologically biocompatible lipids. They have been proven to improve solubility, cellular uptake, and stability, reduce enzyme degradation, and prolong the circulation time of various drugs.
Thi-Thao-Linh Nguyen, Van-An Duong
doaj   +2 more sources

Effects of PEGylated lipid nanoparticles on the oral absorption of one BCS II drug: a mechanistic investigation

open access: yesInternational Journal of Nanomedicine, 2014
Xingwang Zhang,* Guijiang Chen,* Tianpeng Zhang, Zhiguo Ma, Baojian WuDivision of Pharmaceutics, College of Pharmacy, Jinan University, Guangzhou, People’s Republic of China*These authors contributed equally to this workAbstract ...
Zhang XW   +4 more
doaj   +1 more source

Solid Lipid Nanoparticles (SLN): Formulation and Fabrication

open access: yesPharmaceutical Sciences and Research, 2023
Solid lipid nanoparticles (SLN) have emerged as a novel drug delivery system and have been utilized for delivering various kinds of drugs since the 1990s. These particles may consist of multiple solid lipids, including glycerides, waxes, and fatty acids,
Gabriella F. Punu   +5 more
doaj   +1 more source

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