Results 11 to 20 of about 112,460 (251)
Lipid Nanoparticles for the Posterior Eye Segment
Pharmaceutics, 2021 This review highlights the application of lipid nanoparticles (Solid Lipid Nanoparticles, Nanostructured Lipid Carriers, or Lipid Drug Conjugates) as effective drug carriers for pathologies affecting the posterior ocular segment. Eye anatomy and the most
Lorena Bonilla +8 more
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Preclinical Evaluation of Lipid-Based Nanosystems
Pharmaceutics, 2021 The use of lipid-based nanosystems, including lipid nanoparticles (solid lipid nanoparticles—SLN, and nanostructured lipid carriers—NLC), nanoemulsions, and liposomes, among others, is widespread [...]
Ana Catarina Silva +1 more
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Lipid Polymeric Hybrid Nanoparticles: Formulation Techniques and Effects on Glioblastoma [PDF]
Pharmaceutical Sciences, 2022 In the pharmaceutical industry, liposomes and polymeric nanoparticles are the two most commonly studied delivery vehicles. A new technique uses lipid-polymeric hybrid nanoparticles (LPHNPs) with a polymeric core, and a shell made up of lipid-lipid-PEG ...
Yudhishtir Singh Baghel +1 more
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Review article on nanoemulsions and nanostructured lipid carriers [PDF]
Records of Pharmaceutical & Biomedical Sciences, 2018 Lipid nanoparticles, including nanoemulsions (NEs) and nanostructured lipid carriers (NLCs) are colloidal carriers with a lipid matrix that is solid at body temperature.
mamdouh ghorab +3 more
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Editorial—Current Insights on Lipid-Based Nanosystems
Pharmaceuticals, 2022 Lipid-based nanosystems, including solid lipid nanoparticles (SLN) and nanostructured lipid carriers (NLC), cationic lipid nanoparticles, nanoemulsions and liposomes, have been extensively studied to improve drug delivery through different administration
Ana Catarina Silva +2 more
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Use of Microfluidics to Prepare Lipid-Based Nanocarriers
Pharmaceutics, 2023 Lipid-based nanoparticles (LBNPs) are an important tool for the delivery of a diverse set of drug cargoes, including small molecules, oligonucleotides, and proteins and peptides. Despite their development over the past several decades, this technology is
Alicia Vogelaar +4 more
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Journal of Nanobiotechnology, 2022 Liver cancer is considered one of the deadliest diseases with one of the highest disease burdens worldwide. Among the different types of liver cancer, hepatocellular carcinoma is considered to be the most common type. Multiple conventional approaches are
Khaled Mahmoud +3 more
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Lipid–Polymer Hybrid Nanosystems: A Rational Fusion for Advanced Therapeutic Delivery
Journal of Functional Biomaterials, 2023 Lipid nanoparticles (LNPs) are spherical vesicles composed of ionizable lipids that are neutral at physiological pH. Despite their benefits, unmodified LNP drug delivery systems have substantial drawbacks, including a lack of targeted selectivity, a ...
Shweta Jain +6 more
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Computer Simulations of Lipid Nanoparticles [PDF]
Nanomaterials, 2017 Lipid nanoparticles (LNP) are promising soft matter nanomaterials for drug delivery applications. In spite of their interest, little is known about the supramolecular organization of the components of these self-assembled nanoparticles. Here, we present a molecular dynamics simulation study, employing the Martini coarse-grain forcefield, of self ...
Xavier Fernandez-Luengo +2 more
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Experimental and Molecular Medicine, 2023 Several studies have utilized a lipid nanoparticle delivery system to enhance the effectiveness of mRNA therapeutics and vaccines. However, these nanoparticles are recognized as foreign materials by the body and stimulate innate immunity, which in turn ...
Yeji Lee +4 more
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