Results 11 to 20 of about 1,423,524 (284)

Lipid Nanoparticles for Drug Delivery

open access: yesAdvanced NanoBiomed Research, 2022
Lipid nanoparticles have attracted significant interests in the last two decades, and have achieved tremendous clinical success since the first clinical approval of Doxil in 1995.
Letao Xu   +5 more
doaj   +3 more sources

Solid Lipid Nanoparticles vs. Nanostructured Lipid Carriers: A Comparative Review [PDF]

open access: yesPharmaceutics, 2023
Solid–lipid nanoparticles and nanostructured lipid carriers are delivery systems for the delivery of drugs and other bioactives used in diagnosis, therapy, and treatment procedures. These nanocarriers may enhance the solubility and permeability of drugs,
Cláudia Viegas   +5 more
doaj   +2 more sources

Nebulized Lipid Nanoparticles [PDF]

open access: yesNature Reviews Materials, 2021
An article in Nature Biomedical Engineering reports an in vivo workflow for the design of lipid nanoparticles to efficiently deliver mRNA to the lungs via nebulization.
Christine Horejs
exaly   +3 more sources

Lipid Nanoparticles for the Posterior Eye Segment [PDF]

open access: yesPharmaceutics, 2021
This review highlights the application of lipid nanoparticles (Solid Lipid Nanoparticles, Nanostructured Lipid Carriers, or Lipid Drug Conjugates) as effective drug carriers for pathologies affecting the posterior ocular segment. Eye anatomy and the most
Lorena Bonilla   +8 more
doaj   +2 more sources

Advances in Lipid-Based Nanoparticles for Cancer Chemoimmunotherapy [PDF]

open access: yesPharmaceutics, 2021
Nanomedicines have shown great potential in cancer therapy; in particular, the combination of chemotherapy and immunotherapy (namely chemoimmunotherapy) that is revolutionizing cancer treatment.
Tianqi Wang   +5 more
doaj   +2 more sources

Lipid Nanoparticles Functionalized with Antibodies for Anticancer Drug Therapy

open access: yesPharmaceutics, 2023
Nanotechnology takes the lead in providing new therapeutic options for cancer patients. In the last decades, lipid-based nanoparticles—solid lipid nanoparticles (SLNs), nanostructured lipid carriers (NLCs), liposomes, and lipid–polymer hybrid ...
Ana Camila Marques   +3 more
doaj   +2 more sources

Computer Simulations of Lipid Nanoparticles [PDF]

open access: yesNanomaterials, 2017
Lipid nanoparticles (LNP) are promising soft matter nanomaterials for drug delivery applications. In spite of their interest, little is known about the supramolecular organization of the components of these self-assembled nanoparticles. Here, we present a molecular dynamics simulation study, employing the Martini coarse-grain forcefield, of self ...
Xavier Fernandez-Luengo   +2 more
openaire   +6 more sources

Ternary nanoparticles composed of cationic solid lipid nanoparticles, protamine, and DNA for gene delivery

open access: yesInternational Journal of Nanomedicine, 2013
Sai-Nan He,1 Yun-Long Li,1,2 Jing-Jing Yan,2 Wei Zhang,2 Yong-Zhong Du,2 He-Yong Yu,1 Fu-Qiang Hu,2 Hong Yuan21Women’s Hospital, 2College of Pharmaceutical Sciences, School of Medicine, Zhejiang University, Hangzhou, People’s Republic of ...
He SN   +6 more
doaj   +1 more source

Influence of Lipid Matrix Composition on the Intestinal Permeation of Curcumin-Loaded Lipid Nanoparticles [PDF]

open access: yesPharmaceutics
Background: Lipid nanoparticles are widely investigated as oral drug delivery systems, but their intestinal performance remains difficult to predict based only on physicochemical properties.
Anam Sajjad Khan   +2 more
doaj   +2 more sources

Effects of PEGylated lipid nanoparticles on the oral absorption of one BCS II drug: a mechanistic investigation

open access: yesInternational Journal of Nanomedicine, 2014
Xingwang Zhang,* Guijiang Chen,* Tianpeng Zhang, Zhiguo Ma, Baojian WuDivision of Pharmaceutics, College of Pharmacy, Jinan University, Guangzhou, People’s Republic of China*These authors contributed equally to this workAbstract ...
Zhang XW   +4 more
doaj   +1 more source

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