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Several studies have utilized a lipid nanoparticle delivery system to enhance the effectiveness of mRNA therapeutics and vaccines. However, these nanoparticles are recognized as foreign materials by the body and stimulate innate immunity, which in turn ...
Yeji Lee +4 more
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The effect of virgin coconut oil loaded solid lipid particles (VCO-SLPs) on skin hydration and skin elasticity [PDF]
Virgin Coconut Oil is usually extracted from well matured and fresh coconut through specialized processes without damaging its natural nutrition. In this work, formulation, characterization and efficacy of VCO-SLPs have been studied.
Sarmidi, Mohamad Roji +3 more
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Lipid nanoparticles with ionizable lipids: Statistical aspects
Lipid nanoparticles (LNPs) with size ∼100 nm are now used for fabrication of a new generation of drugs and antiviral vaccines. To optimize their function or, more specifically, interaction with cell membranes, their composition often includes ionizable lipids which are neutral or cationic (after association with H^{+}).
openaire +2 more sources
While wogonin has been known to have cytotoxicity against various cancer cells, its bioavailability and cytotoxicity are low due to its low water solubility.
Jong-Suep Baek +2 more
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Copper Nanoparticles Prepared fromOxalic Precursors [PDF]
The synthesis of nanoparticles of copper metal via a soft chemistry route is presented in this paper. The method is based on the thermal decomposition under nitrogen or hydrogen of oxalic precursors with a well-controlled morphology and particle size ...
Philippe Tailhades +5 more
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Lipid Nanoparticles for Gene Delivery [PDF]
Nonviral vectors which offer a safer and versatile alternative to viral vectors have been developed to overcome problems caused by viral carriers. However, their transfection efficacy or level of expression is substantially lower than viral vectors. Among various nonviral gene vectors, lipid nanoparticles are an ideal platform for the incorporation of ...
Yi, Zhao, Leaf, Huang
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Treatment of herpes simplex infection requires high and frequent doses of oral acyclovir to attain its maximum therapeutic effect. The current therapeutic regimen of acyclovir is known to cause unwarranted dose-related adverse effects, including acute ...
Haniza Hassan +5 more
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DBT degradation enhancement by decorating Rhodococcus erythropolis IGST8 with magnetic Fe3O4 nanoparticles [PDF]
Biodesulfurization (BDS) of dibenzothiophene (DBT) was carried out by Rhodococcus erythropolis IGST8 decorated with magnetic Fe3O4 nanoparticles, synthesized in-house by a chemical method, with an average size of 45-50 nm, in order to facilitate the post-
Ansari, Farahnaz +4 more
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Solid lipid nanoparticles promote skin hydration via stratum corneum occlusion, which prevents water loss by evaporation, and via the reinforcement of the skin’s lipid-film barrier, which occurs through the adhesion of the nanoparticles to the stratum ...
Francesca Della Sala +11 more
doaj +1 more source
Poly lactic acid is a biodegradable, biocompatible, and non-toxic polymer, widely used in many pharmaceutical preparations such as controlled release formulations, parenteral preparations, surgical treatment applications, and tissue engineering.
Vivek Dave +5 more
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