Results 41 to 50 of about 1,423,524 (284)

Silica nanoparticles and their interaction with cells : a multidisciplinary approach [PDF]

open access: yes, 2014
Silica nanoparticles are increasingly used as drug delivery systems and for biomedical imaging. Therapeutic and diagnostic agents can be incorporated into the silica matrix to improve the stability and solubility of hydrophobic drugs in biological ...
Kettiger, Hélène Emilie
core   +1 more source

Lipid-Based Nanoparticles in the Clinic and Clinical Trials: From Cancer Nanomedicine to COVID-19 Vaccines

open access: yesVaccines, 2021
COVID-19 vaccines have been developed with unprecedented speed which would not have been possible without decades of fundamental research on delivery nanotechnology.
Thai Thanh Hoang Thi   +5 more
doaj   +1 more source

An insight on lipid nanoparticles for therapeutic proteins delivery [PDF]

open access: yes, 2022
Therapeutic proteins are well-tolerated bioactive compounds used in different therapies, due to its high speci-ficity and biopotency. Nevertheless, they may also present some physicochemical instability, leading to loss of bioactivity hampering ...
Viegas, Cláudia   +2 more
core   +1 more source

Ultrasmall Solid-Lipid Nanoparticles via the Polysorbate Sorbitan Phase-Inversion Temperature Technique: A Promising Vehicle for Antioxidant Delivery into the Skin

open access: yesPharmaceutics, 2023
Solid lipid nanoparticles promote skin hydration via stratum corneum occlusion, which prevents water loss by evaporation, and via the reinforcement of the skin’s lipid-film barrier, which occurs through the adhesion of the nanoparticles to the stratum ...
Francesca Della Sala   +11 more
doaj   +1 more source

Intranasal agomelatine solid lipid nanoparticles to enhance brain delivery: formulation, optimization and in vivo pharmacokinetics [PDF]

open access: yes, 2017
Ahmed M Fatouh,1 Ahmed H Elshafeey,1,2 Ahmed Abdelbary1 1Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Cairo University, Cairo, Egypt; 2School of Pharmacy, University of Waterloo, Waterloo, ON, Canada Purpose: Agomelatine is
Ahmed Fatouh   +5 more
core   +1 more source

Effect of ligand and shell densities on surface structure of core-shell nanoparticles self-assembled from function-spacer-lipid constructs [PDF]

open access: yes, 2023
Biomolecular corona is the major obstacle in clinical translation of nanomedicines. To overcome this problem, comprehensive studies of the processes leading to the formation of a biomolecular corona are required. Since such dynamical studies require high
Anton, Zalygin   +8 more
core   +1 more source

Lipid-polymer hybrid nanoparticles: Development & statistical optimization of norfloxacin for topical drug delivery system

open access: yesBioactive Materials, 2017
Poly lactic acid is a biodegradable, biocompatible, and non-toxic polymer, widely used in many pharmaceutical preparations such as controlled release formulations, parenteral preparations, surgical treatment applications, and tissue engineering.
Vivek Dave   +5 more
doaj   +1 more source

Solid Lipid Nanoparticles and Nanostructured Lipid Carriers: Structure, Preparation and Application [PDF]

open access: yesAdvanced Pharmaceutical Bulletin, 2015
Lipid nanoparticles (LNPs) have attracted special interest during last few decades. Solid lipid nanoparticles (SLNs) and nanostructured lipid carriers (NLCs) are two major types of Lipid-based nanoparticles.
Neda Naseri   +2 more
doaj   +1 more source

The effect of virgin coconut oil loaded solid lipid particles (VCO-SLPs) on skin hydration and skin elasticity [PDF]

open access: yes, 2013
Virgin Coconut Oil is usually extracted from well matured and fresh coconut through specialized processes without damaging its natural nutrition. In this work, formulation, characterization and efficacy of VCO-SLPs have been studied.
Sarmidi, Mohamad Roji   +4 more
core   +1 more source

Solid Lipid Nanoparticles as Innovative Carriers in Drug Delivery: A Review [PDF]

open access: yesالمجلة العراقية للصيدلة
Background: Nanoparticle technology is a new drug delivery system with nano-scale-size. The solid lipid nanoparticles are dynamic systems adopted for formulating water-soluble and insoluble drugs in a colloidal carrier.
Amal Al-Dulaimi   +2 more
doaj   +1 more source

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