Results 31 to 40 of about 1,423,524 (284)

Solid Lipid Nanoparticles: A Potential Approach for Dermal Drug Delivery [PDF]

, 2014
Solid lipid nanoparticles (SLNs) have attracted increasing attention during recent years. Due to their unique size dependent properties, lipid nanoparticles offer possibilities to develop new therapeutics.
Conway, Barbara R, Kakadia, Pratibha G., Kakadia, Partibha, Conway, Barbara; id_orcid   +3 more
core   +1 more source

Lipid based nanoparticles as a novel treatment modality for hepatocellular carcinoma: a comprehensive review on targeting and recent advances

Journal of Nanobiotechnology, 2022
Liver cancer is considered one of the deadliest diseases with one of the highest disease burdens worldwide. Among the different types of liver cancer, hepatocellular carcinoma is considered to be the most common type. Multiple conventional approaches are
Khaled Mahmoud, Shady Swidan, Mohamed El-Nabarawi, Mahmoud Teaima   +3 more
doaj   +1 more source

Lipid–Polymer Hybrid Nanosystems: A Rational Fusion for Advanced Therapeutic Delivery

Journal of Functional Biomaterials, 2023
Lipid nanoparticles (LNPs) are spherical vesicles composed of ionizable lipids that are neutral at physiological pH. Despite their benefits, unmodified LNP drug delivery systems have substantial drawbacks, including a lack of targeted selectivity, a ...
Shweta Jain, Mudit Kumar, Pushpendra Kumar, Jyoti Verma, Jessica M. Rosenholm, Kuldeep K. Bansal, Ankur Vaidya   +6 more
doaj   +1 more source

Immunogenicity of lipid nanoparticles and its impact on the efficacy of mRNA vaccines and therapeutics

Experimental and Molecular Medicine, 2023
Several studies have utilized a lipid nanoparticle delivery system to enhance the effectiveness of mRNA therapeutics and vaccines. However, these nanoparticles are recognized as foreign materials by the body and stimulate innate immunity, which in turn ...
Yeji Lee, Michaela Jeong, Jeongeun Park, Hyein Jung, Hyukjin Lee   +4 more
doaj   +1 more source

Tear of lipid membranes by nanoparticles

Soft Matter, 2022
Tear, a direct physical damage of lipid bilayers, can be inflicted by small enough nanoparticles.
Er-Rafik, Meriem, Ferji, Khalid, Combet, Jérôme, Sandre, Olivier, Lecommandoux, Sébastien, Schmutz, Marc, Le Meins, Jean-François, Marques, Carlos   +7 more
openaire   +4 more sources

DBT degradation enhancement by decorating Rhodococcus erythropolis IGST8 with magnetic Fe3O4 nanoparticles [PDF]

, 2009
Biodesulfurization (BDS) of dibenzothiophene (DBT) was carried out by Rhodococcus erythropolis IGST8 decorated with magnetic Fe3O4 nanoparticles, synthesized in-house by a chemical method, with an average size of 45-50 nm, in order to facilitate the post-
Ansari, Farahnaz, Libor, Zsuzsanna, Grigoriev, P., Ramsden, Jeremy J., Tothill, Ibtisam E.   +4 more
core   +1 more source

Solid Lipid Nanoparticles

Encyclopedia, 2022
Solid lipid nanoparticles (SLNs) are produced from physiologically biocompatible lipids. They have been proven to improve solubility, cellular uptake, and stability, reduce enzyme degradation, and prolong the circulation time of various drugs.
Thi-Thao-Linh Nguyen, Van-An Duong
doaj   +1 more source

Sustained Cytotoxicity of Wogonin on Breast Cancer Cells by Encapsulation in Solid Lipid Nanoparticles

Nanomaterials, 2018
While wogonin has been known to have cytotoxicity against various cancer cells, its bioavailability and cytotoxicity are low due to its low water solubility.
Jong-Suep Baek, Young-Guk Na, Cheong-Weon Cho   +2 more
doaj   +1 more source

On the Structure of Solid Lipid Nanoparticles [PDF]

Small, 2019
AbstractSolid lipid nanoparticles (SLNs) have a crystalline lipid core which is stabilized by interfacial surfactants. SLNs are considered favorable candidates for drug delivery vehicles since their ability to store and release organic molecules can be tailored through the identity of the lipids and surfactants used.
Demi L. Pink, Orathai Loruthai, Robert M. Ziolek, Prawarisa Wasutrasawat, Ann E. Terry, M. Jayne Lawrence, Christian D. Lorenz   +6 more
openaire   +2 more sources

Central Composite Design for Formulation and Optimization of Solid Lipid Nanoparticles to Enhance Oral Bioavailability of Acyclovir

Molecules, 2021
Treatment of herpes simplex infection requires high and frequent doses of oral acyclovir to attain its maximum therapeutic effect. The current therapeutic regimen of acyclovir is known to cause unwarranted dose-related adverse effects, including acute ...
Haniza Hassan, Siti Khadijah Adam, Ekram Alias, Meor Mohd Redzuan Meor Mohd Affandi, Ahmad Fuad Shamsuddin, Rusliza Basir   +5 more
doaj   +1 more source