Results 31 to 40 of about 117,691 (310)
Solid Lipid Nanoparticles and Nanostructured Lipid Carriers: Structure, Preparation and Application [PDF]
Advanced Pharmaceutical Bulletin, 2015 Lipid nanoparticles (LNPs) have attracted special interest during last few decades. Solid lipid nanoparticles (SLNs) and nanostructured lipid carriers (NLCs) are two major types of Lipid-based nanoparticles.
Neda Naseri +2 more
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Lipid Nanoparticles Based Cosmetics with Potential Application in Alleviating Skin Disorders
Cosmetics, 2021 The lipids mainly oils, fats, waxes and phospholipids are of substantial importance in the development and functioning of cosmetic products. The lipid nanoparticles-based cosmetic product is highly capable of protecting the skin against harmful ...
Javed Ahmad
doaj +1 more source
Bulletin of University of Agricultural Sciences and Veterinary Medicine Cluj-Napoca: Food Science and Technology, 2020 Lipid nanoparticles are getting a growing scientific and technological interest, worldwide. Either Solid Lipid Nanoparticles (SLNs), Nanostructured Lipid Carriers (NLCs), Lipid Drug Conjugates (LDCs) or Polymer-Lipid Nanoparticles (PLNs) have been ...
Patricia MUNTEAN +2 more
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Fabrication of active targeting lipid nanoparticles: Challenges and perspectives
Materials Today Advances, 2022 Targeted drug and gene delivery is the key for precision therapy. Lipid nanoparticles as non-viral vectors have attracted extensive attentions in treating a variety of diseases, such as cancer, immune disease, cardiac diseases and pathogen infection ...
Ipshita Menon +4 more
doaj +1 more source
mRNA lipid nanoparticle phase transition
Biophysical Journal, 2022 Crucial for mRNA-based vaccines are the composition, structure, and properties of lipid nanoparticles (LNPs) as their delivery vehicle. Using all-atom molecular dynamics simulations as a computational microscope, we provide an atomistic view of the structure of the Comirnaty vaccine LNP, its molecular organization, physicochemical properties, and ...
Trollmann, Marius F.W. +1 more
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Cosmetics, 2021 Limited permeability through the stratum corneum (SC) is a major obstacle for numerous skin care products. One promising approach is to use lipid nanoparticles as they not only facilitate penetration across skin but also avoid the drawbacks of ...
Dima Khater +7 more
doaj +1 more source
Lipid-based nanoparticles as novel drug delivery systems for antimicrobial agents [PDF]
The Iranian Journal of Veterinary Science and Technology, 2018 Despite the development of novel drugs and technologies in combating the infectious diseases, they remain as a global health challenge. The use of conventional antimicrobial drugs are always associated with problems such as antimicrobial resistance ...
Ali Rassouli, Alwan Al-Qushawi
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From lipids to lipid nanoparticles to mRNA vaccines [PDF]
Nature Reviews Materials, 2021 Lipid nanoparticles are essential to mRNA vaccines. The groundwork for lipid-based drug delivery systems was laid more than 40 years ago in the lab of Pieter Cullis, Professor at the University of British Columbia. Nature Reviews Materials talks to Pieter Cullis about the history and future of lipid nanoparticle-nucleic acid drugs.
openaire +2 more sources
Export of miRNAs from activated macrophages is cooperative and HuR‐dependent
FEBS Letters, EarlyView.This study uncovers a new mechanism for miRNA export regulation in mammalian cells, driven by the RNA‐binding protein HuR. In macrophages, HuR cooperatively binds with miRNAs to export both low‐ and high‐affinity substrates, thereby influencing macrophage activation.
Syamantak Ghosh +2 more
wiley +1 more source
High-Resolution Characterization of Protein-Conjugated, mRNA-Loaded Lipid Nanoparticles by Analytical Ultracentrifugation. [PDF]
Adv Funct MaterLipid nanoparticles containing messenger RNA are characterized by sedimentation velocity analytical ultracentrifugation using UltraScan's new Custom Grid algorithm to provide multi‐dimensional distributions for partial specific volume (particle density), molar mass, sedimentation, diffusion, and hydrodynamic radius.
Bird S +8 more
europepmc +2 more sources