Results 121 to 130 of about 273,083 (353)

HNRNPU K181 Lactylation Drives Cervical Cancer Growth by Upregulating PHGDH and Reprogramming Serine Metabolism

Advanced Science, EarlyView.
Lactate in cervical cancer induces HNRNPU K181 lactylation, opposed by NAA50‐mediated acetylation and suppressed by Pazopanib. This lactylation enhances HNRNPU binding to PHGDH pre‐mRNA exon 1, maintaining exon 1‐containing transcripts and mRNA stability, thereby activating serine metabolism.
Chang Zhang, Qingfei Meng, Hui Jiao, Huixin Liu, Xiangchao Wang, Honglan Zhou, Yishu Wang   +6 more
wiley   +1 more source

Lipid peroxidation and tissue damage

, 1999
In recent years it has become apparent that the oxidation of lipids, or lipid peroxidation, is a crucial step in the pathogenesis of several disease states in adult and infant patients. Lipid peroxidation is a process generated naturally in small amounts
Kouretas, D., Mylonas, C.
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Lipid Peroxidation-Related Redox Signaling in Osteosarcoma

Oxidative stress and lipid peroxidation play important roles in numerous physiological and pathological processes, while the bioactive products of lipid peroxidation, lipid hydroperoxides and reactive aldehydes, act as important mediators of redox ...
Neven Žarković, Morana Jaganjac, Suzana Borović Šunjić, Mirna Halasz, Josipa Vlainić   +4 more
core   +1 more source

THE ROLE OF LIPID PEROXIDATION IN INFLAMMATION

, 2022
The article analyzes the literature and our own research on the role of the lipid peroxidation during inflammation. There is a direct connection and dependence between the severity of the inflammatory reaction and the degree of activation of lipid ...
Nina Vladimirovna Tregubova
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Status of lipid peroxidation and antioxidant enzymes in goats naturally infected with Babesia ovis [PDF]

, 2012
Bijan Esmaeilnejad, Mousa Tavassoli, Siamak Asri‐Rezaei, Bahram Dalir‐Naghadeh, Hassan Malekinejad   +4 more
openalex   +1 more source

A Review on Catalytic Nanostructured Electrodes for Wearable and Implantable Abiotic Glucose Fuel Cells

Advanced Science, EarlyView.
This review identifies current and future directions in abiotic nanostructured catalysts to develop reliable and sustainable glucose fuel cells to power the next generation of bioelectronic devices. ABSTRACT The global rise in incidence of chronic diseases has led to the demand for innovative solutions that help patients manage their conditions with ...
Asghar Niyazi, Hannah S. Leese, Benjamin Metcalfe, Mirella Di Lorenzo   +3 more
wiley   +1 more source

Lipid peroxidation in different diseases: A review

, 2016
Variation in lipid peroxidation levels are observed in different diseases. Many studies have shown that increased lipid peroxidation is associated with occurrence of some diseases. The aim of present effort was to review the role of lipid peroxidation in
Marjani, A.
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933 Nitric Oxide and Lipid Peroxidation are Increased and Associated with Decreased Antioxidant Enzyme Activities in Children with Nosocomial Pneumonia [PDF]

, 2010
Dmytro Dmytrіiev, Oleksandr Katilov, Kateryna Dmytriіeva   +2 more
openalex   +1 more source

Disruption of Treg Homeostasis in Rheumatoid Arthritis via Ferroptosis‐Mediated ETC Collapse and TXK‐STAT3/PLCγ1 Activation

Advanced Science, EarlyView.
In rheumatoid arthritis, synovial Tregs accumulate but are functionally impaired due to iron overload‐induced ferroptosis. This triggers mitochondrial dysfunction and TXK tyrosine kinase‐mediated signaling, leading to Treg destabilization and inflammation.
Jingrong Chen, Xiao Guan, Kexu Xiong, Xiaoyi Shi, Luyao Wu, Chuanxin Su, Jun Zhao, Rongzhen Liang, Huimin Wang, Junlong Dang, Ye Chen, Yiding Xiong, Chi Zhou, Futao Zhao, Zhenhang Zhu, Xiaoli Fan, Li Zhou, Nancy Olsen, Yutong Jiang, Song Guo Zheng   +19 more
wiley   +1 more source

Unravelling lipid peroxidation in Cystic Fibrosis using a pharmacological approach

reservedLa Fibrosi Cistica (FC) è la malattia autosomica recessiva più comune nella popolazione caucasica. Dal punto di vista molecolare, questa patologia è causata da problematiche a livello del canale CFTR, che è il principale trasportatore ...
CRAVIN, GIOVANNI
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