Results 101 to 110 of about 248,429 (304)

Triglyceride peroxidation progression in lipid droplets of hepatocytes in nonalcoholic steatohepatitis

open access: yesRedox Experimental Medicine
Objective: Nonalcoholic steatohepatitis is a chronic liver disease caused by the progression of hepatocellular death and inflammation from simple steatosis. However, the pathogenesis of this disease remains unclear.
Kota Saito   +5 more
doaj   +1 more source

Adipocyte‐Derived Leptolin Enhances Energy Expenditure and Prevents Obesity

open access: yesAdvanced Science, EarlyView.
We identified a novel adipokine, which we named leptolin. In humans, leptolin levels in white adipose tissue were positively correlated with exercise and negatively associated with body mass index. We observed elevated leptolin in serum from athletes and lower leptolin in serum from obese individuals.
Jiarui Liu   +17 more
wiley   +1 more source

Lipid peroxidation in different diseases: A review [PDF]

open access: yes, 2016
Variation in lipid peroxidation levels are observed in different diseases. Many studies have shown that increased lipid peroxidation is associated with occurrence of some diseases. The aim of present effort was to review the role of lipid peroxidation in
Marjani, A.
core  

Acid phosphatase and lipid peroxidation in human cataractous lens epithelium

open access: yesIndian Journal of Ophthalmology, 1993
The anterior lens epithelial cells undergo a variety of degenerative and proliferative changes during cataract formation. Acid phosphatase is primarily responsible for tissue regeneration and tissue repair.
Vasavada Abhay   +3 more
doaj  

ACSL4 at the helm of the lipid peroxidation ship: a deep-sea exploration towards ferroptosis

open access: yesFrontiers in Pharmacology
Lipid peroxidation stands as a prominent hallmark and a prerequisite for the onset of ferroptosis. Lipid metabolism holds a pivotal role in regulating this process, forming the metabolic foundation for cellular sensitivity to ferroptosis.
Yulang Jiang   +8 more
doaj   +1 more source

Phosphorylation‐Facilitated CKB Lactylation At K11 By GCN5 Enhances Creatine Kinase Activity and Mitigates Neuronal Damage After Cerebral Ischemia‐Reperfusion

open access: yesAdvanced Science, EarlyView.
This study uncovers hierarchical coordination between K11 lactylation and S199 phosphorylation of CKB in cerebral ischemia‐reperfusion injury. Such dual modifications potentiate CKB enzymatic function, remodel energy metabolism, alleviate oxidative stress and neuronal damage, and represent a viable therapeutic target for stroke treatment.
Chao Duan   +17 more
wiley   +1 more source

Unravelling lipid peroxidation in Cystic Fibrosis using a pharmacological approach [PDF]

open access: yes
reservedLa Fibrosi Cistica (FC) è la malattia autosomica recessiva più comune nella popolazione caucasica. Dal punto di vista molecolare, questa patologia è causata da problematiche a livello del canale CFTR, che è il principale trasportatore ...
CRAVIN, GIOVANNI
core  

HNRNPU K181 Lactylation Drives Cervical Cancer Growth by Upregulating PHGDH and Reprogramming Serine Metabolism

open access: yesAdvanced Science, EarlyView.
Lactate in cervical cancer induces HNRNPU K181 lactylation, opposed by NAA50‐mediated acetylation and suppressed by Pazopanib. This lactylation enhances HNRNPU binding to PHGDH pre‐mRNA exon 1, maintaining exon 1‐containing transcripts and mRNA stability, thereby activating serine metabolism.
Chang Zhang   +6 more
wiley   +1 more source

Parâmetros de funcionalidade de células mononucleares, de estresse oxidativo, proteínas de fase aguda e estado nutricional de indivíduos portadores de neoplasias hematológicas antes do tratamento quimioterápico [PDF]

open access: yes, 2014
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde, Programa de Pós-Graduação em Nutrição, Florianópolis, 2013.Neoplasias hematológicas são cânceres que se iniciam em tecidos produtores de células sanguíneas e no
Camargo, Carolina de Quadros
core  

A Review on Catalytic Nanostructured Electrodes for Wearable and Implantable Abiotic Glucose Fuel Cells

open access: yesAdvanced Science, EarlyView.
This review identifies current and future directions in abiotic nanostructured catalysts to develop reliable and sustainable glucose fuel cells to power the next generation of bioelectronic devices. ABSTRACT The global rise in incidence of chronic diseases has led to the demand for innovative solutions that help patients manage their conditions with ...
Asghar Niyazi   +3 more
wiley   +1 more source

Home - About - Disclaimer - Privacy