Results 81 to 90 of about 248,429 (304)

Peroxiredoxin 6 phospholipid hydroperoxidase activity in the repair of peroxidized cell membranes

open access: yesRedox Biology, 2018
Although lipid peroxidation associated with oxidative stress can result in cellular death, sub-lethal lipid peroxidation can gradually resolve with return to the pre-exposure state.
Aron B. Fisher   +5 more
doaj   +1 more source

CMS121, a fatty acid synthase inhibitor, protects against excess lipid peroxidation and inflammation and alleviates cognitive loss in a transgenic mouse model of Alzheimer's disease

open access: yesRedox Biology, 2020
The oxidative degradation of lipids has been shown to be implicated in the progression of several neurodegenerative diseases and modulating lipid peroxidation may be efficacious for treating Alzheimer’s disease (AD).
Gamze Ates   +3 more
doaj   +1 more source

A Naphthalimide‐Based NIR‐Emissive AIE Photosensitizer for Synergistic Apoptosis/Ferroptosis‐Mediated Antitumor Therapy and Broad‐Spectrum Bacterial Inactivation With Rapid Wound Healing

open access: yesAdvanced Healthcare Materials, EarlyView.
An ionic naphthalimide AIE photosensitizer (PS), TPAPV‐NIM‐M, anchors to cellular and bacterial membranes, emits in the far‐red/near‐infrared (NIR) region, and efficiently generates reactive oxygen species (ROS) under white light. Its membrane‐localized photodynamic action drives apoptosis/ferroptosis‐mediated tumor suppression and broad‐spectrum ...
Sayed Mir Sayed   +3 more
wiley   +1 more source

Ascorbic Acid, Lipid Peroxidation, and Aging [PDF]

open access: yes, 1979
The role of ascorbic acid with regard to lipid peroxidation and aging has been examined. A thorough literature analysis indicates that free radical-induced lipid peroxidation is a plausible biochemical explanation for aging.
Leibovitz, Brian Evan
core   +2 more sources

SLC27A2 marks lipid peroxidation in nasal epithelial cells driven by type 2 inflammation in chronic rhinosinusitis with nasal polyps

open access: yesExperimental and Molecular Medicine
Chronic rhinosinusitis with nasal polyps (CRSwNP) is characterized by persistent inflammation and epithelial cell dysfunction, but the underlying molecular mechanisms remain poorly understood. Here we show that dysregulated lipid metabolism and increased
Jaewoo Park   +9 more
doaj   +1 more source

Enhancement of lipid peroxidation and its amelioration by vitamin E in a subject with mutations in the SBP2 gene[S]

open access: yesJournal of Lipid Research, 2015
Selenocysteine (Sec) insertion sequence-binding protein 2 (SBP2) is essential for the biosynthesis of Sec-containing proteins, termed selenoproteins. Subjects with mutations in the SBP2 gene have decreased levels of several selenoproteins, resulting in a
Yoshiro Saito   +10 more
doaj   +1 more source

Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy

open access: yesAdvanced Materials, EarlyView.
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa   +3 more
wiley   +1 more source

Mesoporous Silica Nanoparticles in Biomedicine: Advances and Prospects

open access: yesAdvanced Materials, EarlyView.
Mesoporous silica nanoparticles offer unique properties like high surface area, tunable pores, and functionalization. They excel in drug delivery, tissue engineering, and stimuli‐responsive therapies, enabling targeted and controlled treatments. With roles in cancer therapy and diagnostics, their clinical translation requires addressing challenges in ...
Miguel Manzano, María Vallet‐Regí
wiley   +1 more source

Blood Viscosity, Lipid Profile and Lipid Peroxidation in Type-1 Diabetic Patients with Good and Poor Glycemic Control: The Promise and Reality [PDF]

open access: yes, 2013
This issue of the journal brings a paper with strong perspective in practice - “Blood Viscosity, Lipid Profile, and Lipid Peroxidation in Type-1 Diabetic Patients with Good and Poor Glycemic Control.”[1] Patients with diabetes show lipid disorders that ...
Nwose, Ezekiel Uba
core  

Lipid Peroxidation Research [PDF]

open access: yes, 2020
Lipid peroxidation is the major molecular mechanism that induces oxidative damage to cell structures and is also involved in the toxicity process that leads to cell death.Lipid peroxidation is a chain reaction initiated by the hydrogen abstraction or ...

core   +1 more source

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